암센서용 TiO2/Au/CNT 나노복합물의 전기화학적 검출

홍성미, 김홍일, 김한주, Wang, Xuemei, 박수길 충북대학교 건설기술연구소 2008 충북대학교 건설기술연구소 논문집 Vol.27 No.1

Demand of rapid detection for cancer, it is necessary that high sensitivity, specificity, low cost, and simple method. CNT and metal nano materials are widely used to elecate efficient. CNT have various advantage, and can be composed with metal nano materials. Especially, Titanium oxide and gold nano particles are focused on sensor for detection of cancer, it can elecate electron transition feeiciency between electrode surface and target materials, and biological functionalization of CNT. It means that nano material is composed each other. In this study, electrodes are considered materialsd and their chracteristic for cancer sensor.

정신분열증 환자에 있어서 비관척도의 인자분석 연구

왕성근,지익성 충남대학교 의과대학 지역사회의학연구소 1987 충남의대잡지 Vol.14 No.2

To investigate the components of the hopelessness in schizophrenia, the authors applied the korean version of Beck's the Hopeless Scale on the 57 schizophrenic patients, and tried factor analysis using SPSS/PC+based on the scores of each items. The results of factor analysis were summarised as following 5 factors : Factor 1 was lack of confidence factor, factor 2 was despair factor, factor 3 was frustration factor, factor 4 was worthlessness factor and factor 5 was negative view factor. These results were thought to be as the concentration of the hopelessness in schizophrenia.

인격장애척도의 표준화에 관한 연구 : 대전시내 중·고등학생을 중심으로

왕성근 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2

For the purpose of standardization of Personality Deviance Scale, the author applied Korean version of Personality Deviance Scale to the 600 middle and high school students in Taejon city from March, 1985 to May, 1985. The results were summarized as follows. 1. In middle school students group, the mean score of 3 major scales were Extrapunitive scale 25.70 Intropunitive scale 25.57 and Dominance scale 24.36 and total mean score was 51.63. 2. In high school students group, the mean score of 3 major scales were Extrapunitive scale 26.39, Intropunitive scale 25.90 and Dominance scale 25.00 and total mean score was 53.56. 3. The significance between 3 major scales were as follows; There was no significance between Extrapunitiveness and Intropunitiveness and partially significant between Intropunitiveness and Dominance but, marked signficant in all age groups between Extrapunitiveness and Dominance scale. Above results were regarded as reliable standard of Personality Deviance Scale for the middle and high school students but, further study should be made for adults and female subjects.

인격장애척도의 표준화에 관한 연구 : 대전시내 여자 중·고등학생을 중심으로

왕성근,추호상 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

For the purpose of standardization of Personality Deviance Scale, authors applied Korean version of Personality Deviance Scale to the 600 middle and high school girl students in Taejon city from March to June, 1986. The results were summarized as follows: 1. In the middle school students group, the mean score and standard deviation of 3 major scales were Extrapunitive scale 33.98±12.26, Intropunitive scale 25.08±13.24 and Dominance scale 33.66±10.08 and total mean score and standard deviation was 92.72±10.27. 2. In the high school students group, the mean score and standard deviation were Extrapunitive scale 32.67±11.32, Intropunitive scale 25.67±13.47, Dominance scale 34.24±10.22 and total mean score and standard deviation was 92.59±10.53. 3. The significance among 3 major scales were as follows; In each middle and high school grades, there was no significance between Extrapunitiveness vs Dominance, and in all grades, there were marked significance between Extrapunitiveness vs Intropunitiveness and Intropunitiveness vs Dominance (p<0.005).

精神分裂病의 現象學的 硏究

王成槿,申石澈 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.2

This study was attempted to investigate the schizophrenic phenomena : symptoms, psychological impairment, and diagnosis and treatment, systematically and objectively. 72 schizophrenic patients(43 males, 29 females) on Screening Schedule were applied Present State Examination, Psychological Impairment Rating Schedule, Scale for the Assessment of Negative Symptoms, Diagnostic and Prognostic Schedule, and tried factor analysis with statistical package for the social sciences based on the scores of each item. The results of factor analysis of the schizophrenic phenomenology were summarized as following 4 factors : Factor 1 was composed of psychological impairments in activity/withdrawal, social skills and negative symptoms, naming psychological impairment associated with negative symptom factor, factor 2 was composed of neurotic symptoms, psychotic symptoms and other psychotic symptoms in Present State Examination and pure psychotic symptoms, naming overt psychotic symptom factor, factor 3 was composed of remission or exacervation of psychosis with or without personality change during following 5 years, naming long-term prognosis factor, factor 4 was composed of the occupational capacity and the level of family/household functioning during following 12 months as capable to work under sheltered condition only and mildly impaired, naming social impairment factor. From the above results, it was suggested that these factors were the concentration of the schizophrenic phenomena.

일부 남자 젊은 성인에 있어서 수면에 대한 Phenobarbital의 효과

왕성근,김덕호 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.5

To identify the effects of phenobarbital on the sleep patterns. the author applied polysomnography to the 15 healthy male young adults. The subjects were examined before and after intravenous injection of the phenobarbital-sodium(100mg). Compared to baseline. sleep continuities and sleep stages were changed after injection of the phenobarbital. Sleep latency was decreased. Stage 2 sleep and 4th & 5th fractions of REM cycle were increased. These changes were statistically significant with p<0.05 and p<0.005 respectively. TST, SE, REM latency & REM cycle tended to increase and W.A.S.O., stage 1 sleep time, average REM sleep time & REN number tended to dcrease, but these effects were not statistically significant. 1st, 2nd & 3rd fractions of REM duration tended to shorten and 4th & 5th fractions of REM duration tended to lengthen,but these effects were not statistically significant. During the first half of the night, SWT tended to increase and WASO tended to decrease, but these effects were not statistically significant. Average REM duration, SWT, 1st, 2nd & 3rd fractions of REM cycle and SWT & WASO during the last half of night were not different. These results were consistent with the reports of previous studies.

부분적 수면박탈이 주간 기분과 반응시간에 미치는 영향

왕성근 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

To identify the effects of partial sleep deprivation on daytime mood and reaction time, visual analogue scales and reaction time applied to normal healtly young adults, ranging in age from 20 years to 25 years, with no past or present histories of significant medical, neurological, or psychiatric illness as well as no current major sleep disturbances or parasomnias. During daytime after successive 3 nights of partial sleep deprivation and one night of recovery sleep, each subject completed visual analogue scales and reaction time 4 times(at 09 : 00, 12 : 00, 15 : 00, and 18 : 00), and tried paired t-test. Results are summarized as follows. 1. Compaired with baseline, mood was significantly worse during daytime after 3 days of sleep deprivation and nearly complete recovered after 1 night of recovery sleep. 2. Compared with the baseline, reaction time was significantly delayed during daytime after 3 days of partial sleep deprivation and returned to normal level after 1 night of recovery sleep.

다원수면기록에 의한 한국인 20대 정상 성인의 수면에 관한 연구

왕성근,김상국 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.5

Polysomnography has been increasingly used for the purpose of clinical study and basic research. But, until now, there has been no polysomnographic study on the normal control and sleep disorders in Korea. The authors tried polysomnographic study to establish the reference data of normal young Koreans. The subjects were 18 healthy young adults. ranging in age from 19 years to 27 years. without past or present histories of significant medical. neurological. or psychiatric illness. They did not have current major sleep disturbances or parasomnias. Each subject stayed one night for adaptation before recording started. We tried to conform to each subject’s normal sleep schedule as much as possible. Electrode placement〔two unipolar electroence-phalographic leads (C₃,C₄)〕,two unipolar electro-oculogram (right and left outer canthi), and bipolar electromyographic leads(submentalis muscle)〕and scoring were carried out by the methods of Rechtschaffen and Kale. The results were summarized as follows. 1) The average total sleep time was 443.6 minutes and sleep efficiency was 92.2%. 2) The average sleep latency was 13.8 minutes and REM latency was 105.4 minutes. 3) The number of REM sleep was 4.6 times average, mean REM duration was 22.5 minutes. mean REM cycle was 92.8 minutes. 4) The fractions of each sleep stage to TST were as follows; stage 1 was 13.6%, stage 2 was 44.7%, stage 3 was 12.3%, stage 4 was 6.6% and REM stage was 22.8% 5) The slow wave sleep was concentrated in the first half of the night and REM sleep was concentrated in the last half of the night.

수면무호흡증의 임상적 고찰 : 다원수면기록소견을 중심으로

왕성근 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

To identify the clinical characteristics of sleep apnea syndrome in korean, author tried statistical analysis of 24 cases of polysomnographic findings diagnosed as sleep apnea syndrome during December, 1993 to November, 1994. The results were summarized as follows. 1. Distribution of the subtypes of sleep apnea syndrome according to AI, the obstructive type was 23 cases, central type was 4 cases and mixed type was 6 cases, and most frequent dominant type was obstructive type. 2. As for sleep parameters, mean total sleep time was 303.6 minutes, WASO was 123.8 minutes, movement time was 6.2 minutes, sleep efficiencies was 71.3%, stage 1 sleep time was 58.8 minutes (19.4%), stage 2 sleep time was 136.2 minutes(44.9%), slow wave sleep time was 53.5 minutes(17.6%), REM sleep time was 49.4 minutes(16.3%), and non-REM sleep time was 248.5 minutes(81.9%). 3. Correlations among sleep parameters diagnosed as obstructive type SAS, WASO was negative correlation with total sleep time, non-REM sleep time was positive correlation with total sleep time and negative correlation with WASO. Sleep efficiencies was positive correlation with total sleep time and non-REM sleep time, and negative correlation with WASO. And, slow wave sleep time was negative correlation with stage 1 sleep time and stage 2 sleep time. Above results were thought to be as useful data in clinical practice for the explanation of characteristics of korean sleep apnea syndrome.

정상인에서 부분적 수면박탈이 수면구조에 미치는 영향

왕성근,이정규,이충숙,최하석,유남재,정인형,이선우 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

To identify the effects of partial sleep deprivation on the sleep structure, the authors performed polysomnographic study for 9 healthy young adults. The subjects were college students, ranging in age from 20 to 25 years, without personal past or present histories of medical, neurological, or psychiatric illness and suffering from current sleep disturbance or parasomomnias. Sleep records were analyzed according to the criteria of Rechtschaffen and Kales' manual and tried paired t-test. The results were summarized as follows. 1. As for sleep parameters, total sleep time(TST), REM latency and REM duration were not changed significantly during deprivation period and recovery period compared with baseline. Sleep efficiency increased significantly during deprivation period and recovery period compaired with baseline, and sleep latency and WASO were shortened significantly during deprivation period and recovery period compared with baseline. 2. As for sleep structure, 1) The absolute value(minutes) of stage 1 decreased significantly during deprivation period and first recovery night compared with baseline, and the relative value(percentage) of stage 1 decreased significantly during deprivation period and recovery period compared with baseline. 2) The absolute value(minutes) of stage 2 decreased significantly during deprivation period compared with baseline, and the relative value(percentage) of stage 2 decreased significantly during deprivation period and first recovery night compared with baseline. 3) The absolute value(minutes) of slow wave sleep were not changed significantly during deprivation period and recovery period compared with baseline, and the relative value(percentage) of slow wave sleep increased significantly during recovery period compared with baseline. 4) The absolute value(minutes) of REM sleep decreased significantly during deprivation period compared with baseline, and the relative value(percentage) of REM sleep decreased significantly in the first deprivation night but, were not changed significantly during recovery period compared with baseline.