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Stage-dependent gene expression profiles during natural killer cell development
Kang, Hyung-Sik,Kim, Eun-Mi,Lee, Sanggyu,Yoon, Suk-Ran,Kawamura, Toshihiko,Lee, Young-Cheol,Kim, Sangsoo,Myung, Pyung-Keun,Wang, San Ming,Choi, Inpyo Elsevier 2005 Genomics Vol.86 No.5
<P><B>Abstract</B></P><P>Natural killer (NK) cells develop from hematopoietic stem cells (HSCs) in the bone marrow. To understand the molecular regulation of NK cell development, serial analysis of gene expression (SAGE) was applied to HSCs, NK precursor (pNK) cells, and mature NK cells (mNK) cultured without or with OP9 stromal cells. From 170,464 total individual tags from four SAGE libraries, 35,385 unique genes were identified. A set of genes was expressed in a stage-specific manner: 15 genes in HSCs, 30 genes in pNK cells, and 27 genes in mNK cells. Among them, lipoprotein lipase induced NK cell maturation and cytotoxic activity. Identification of genome-wide profiles of gene expression in different stages of NK cell development affords us a fundamental basis for defining the molecular network during NK cell development.</P>
AKARI INFRARED CAMERA SURVEY OF THE LARGE MAGELLANIC CLOUD. I. POINT-SOURCE CATALOG
Kato, Daisuke,Ita, Yoshifusa,Onaka, Takashi,Tanabé,, Toshihiko,Shimonishi, Takashi,Sakon, Itsuki,Kaneda, Hidehiro,Kawamura, Akiko,Wada, Takehiko,Usui, Fumihiko,Koo, Bon-Chul,Matsuura, Mikako,Tak American Institute of Physics 2012 The Astronomical journal Vol.144 No.6
<P>We present a near- to mid-infrared point-source catalog of five photometric bands at 3.2, 7, 11, 15, and 24 μm for a 10 deg<SUP>2</SUP> area of the Large Magellanic Cloud (LMC) obtained with the Infrared Camera on board the AKARI satellite. To cover the survey area the observations were carried out at three separate seasons from 2006 May to June, 2006 October to December, and 2007 March to July. The 10σ limiting magnitudes of the present survey are 17.9, 13.8, 12.4, 9.9, and 8.6 mag at 3.2, 7, 11, 15, and 24 μm, respectively. The photometric accuracy is estimated to be about 0.1 mag at 3.2 μm and 0.06-0.07 mag in the other bands. The position accuracy is 0<img entity='farcs' SRC='http://ej.iop.org/icons/Entities/farcs.gif' ALT='farcs' ALIGN='BOTTOM' />3 at 3.2, 7, and 11 μm and 1<img entity='farcs' SRC='http://ej.iop.org/icons/Entities/farcs.gif' ALT='farcs' ALIGN='BOTTOM' />0 at 15 and 24 μm. The sensitivities at 3.2, 7, and 24 μm are roughly comparable to those of the Spitzer SAGE LMC point-source catalog, while the AKARIcatalog provides the data at 11 and 15 μm, covering the mid-infrared spectral range contiguously. Two types of catalog are provided: a Catalog and an Archive. The Archive contains all the detected sources, while the Catalog only includes the sources that have a counterpart in the Spitzer SAGE point-source catalog. The Archive contains about 650,000, 140,000, 97,000, 43,000, and 52,000 sources at 3.2, 7, 11, 15, and 24 μm, respectively. Based on the catalog, we discuss the luminosity functions at each band, the color-color diagram, and the color-magnitude diagram using the 3.2, 7, and 11 μm band data. Stars without circumstellar envelopes, dusty C-rich and O-rich stars, young stellar objects, and background galaxies are located at distinct regions in the diagrams, suggesting that the present catalog is useful for the classification of objects toward the LMC.</P>