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( So Yi Lim ),( Seung Yeon Ha ),( Kwang Beom Lee ),( Ji Sung Lee ) 대한산부인과학회 2013 Obstetrics & Gynecology Science Vol.56 No.3
Placenta accreta during the first trimester of pregnancy is rare. Only a few cases of placenta accreta manifesting as a uterine mass have been published. Most patients with placenta accreta present with vaginal bleeding during or after pregnancy. This report describes a patient with placenta accreta that caused vaginal bleeding three years after a first trimester abortion. The patient had regular menstruation for three years after the abortion. Initially endometrial cancer or a uterine myoma with degeneration was suspected. This is the first report of a placenta accreta detected as a uterine mass long after a first trimester abortion with delayed vaginal bleeding.
( So Yi Lim ),( Na Rae Kim ),( Kwang Beom Lee ) 대한산부인과학회 2013 Obstetrics & Gynecology Science Vol.56 No.3
Sertoli-Leydig tumors tend to relapse early and due to their rarity, limited data are available regarding a role of chemotherapy in the management of Sertoli-Leydig cell tumors. We present a case of recurrent ovarian Sertoli-Leydig cell tumor whose salvage treatment was successful with paclitaxel and carboplatin chemotherapy.
( So Yi Lim ),( Seung Ho Lee ),( Kwang Beom Lee ),( Chan Yong Park ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-
The objective of this study is to evaluate correlation of preoperative anemia with clinical outcomes in patients with early stage cervical cancer who were treated with radical hysterectomy and lymph node dissection. Patients who underwent radical hysterectomy and lymph node dissection for cervical cancer from January 2001 to February 2012 were included in this study. Clinicopatholgoical factors included in univariate and multivariate analysis were age, tumor histology, FIGO stage, preoperative hemoglobin, depth of invasion, tumor size, parametrial involvement, resection margin, and lymph node status. The endpoint of the study was relapse-free survival (RFS) and overall survival (OS). A total of 387 patients were retrospectively analyzed in this study; 141 patients (36.4%) had preoperative anemia (Hb<12g/dL) and 16 out of 141 patients (11.3%) received blood transfusion for correction of preoperative anemia. Patients with preoperative anemia showed significant association with age <50 years, more advanced stage, non- squamous cell carcinoma histology, larger tumor size, deeper stromal invasion, and lymph node metastasis. Both RFS and OS were worse in patients with preoperative anemia. In the intergroup analysis of anemic patients for the effect of preoperative blood transfusion, preoperative anemia correction did not affect survival. Our data suggest that preoperative anemia could represent an important prognostic factor in patients with early cervical cancer who underwent radical hysterectomy and lymph node dissection. Correction of anemia with blood transfusion in the preoperative setting did not affect the clinical outcomes.
( So Yi Lim ),( Seok-ho Lee ),( Kwang Beom Lee ),( Chan-yong Park ) 대한산부인과학회 2016 Obstetrics & Gynecology Science Vol.59 No.3
Objective The purpose of this study was to evaluate the prognosis according to the number of high risk factors in patients with high risk factors after radical hysterectomy and adjuvant chemoradiation therapy for early stage cervical cancer. Methods Clinicopathological variables and clinical outcomes of patients with FIGO (International Federation of Gynecology and Obstetrics) stage IB1 to IIA cervical cancer who had one or more high risk factors after radical hysterectomy and adjuvant chemoradiation therapy were retrospectively analyzed. Patients were divided into two groups according to the number of high risk factors (group 1, single high risk factor; group 2, two or more high risk factors). Results A total of 93 patients were enrolled in the present study. Forty nine out of 93 (52.7%) patients had a single high risk factor, and 44 (47.3%) had two or more high risk factors. Statistically significant differences in stage and stromal invasion were observed between group 1 and group 2. However, age, histology, tumor size, and lymphovascular space invasion did not differ significantly between the groups. Distant recurrence occurred more frequently in group 2, and the probability of recurrence and death was higher in group 2. Conclusion Patients with two or more high risk factors had worse prognosis in early stage cervical cancer. For these patients, consideration of new strategies to improve survival may be worthwhile. Conduct of further clinical trials is warranted for development of adjuvant treatment strategies individualized to each risk group.