편두통의 진단과 치료

주민경 대한가정의학회 2006 Korean Journal of Family Medicine Vol.27 No.6

편두통은 일상생활에 상당한 장애를 줄 수 있는 흔한 두통 질환이다. 편두통의 진단은 2004년에 제정된 국제두통질환분류의 진단기준이 흔히 사용된다. 편두통의 치료에는 약물적 치료와 비약물 치료가 있고 약물 치료에는 급성기 치료와 예방 치료가 있다. 급성기 치료에는 두통이 발생 시에 투여하여 빨리 두통을 약화시키거나 소실시키는 치료로 아스피린, 아세트아미노펜, NSAIDs, 진토제 등의 비특이 약물과 에르고트제와 트립탄제 등의 편두통 특이 약물이 사용된다. 편두통의 발작이 자주 있어서 일상생활에 장애가 상당하거나 급성기 치료 약물에 반응하지 않거나 사용할 수 없는 경우에는 예방 치료를 시행한다. 예방 치료에는 항경련제, 항우울제, 베타차단제, 칼슘통로길항제 등이 사용된다. 편두통의 비약물적인 치료로는 유발요인제거 또는 회피, 생활습관의 변화, 생체되먹이기(biofeedback), 이완요법 등이 있다. 각 환자의 편두통의 정확한 파악과 적절한 치료법과 약물의 사용으로 보다 효과적으로 편두통을 치료할 수 있을 것이다.

노인들의 여가활동 참여여부와 활동유형에 따른 성공적 노화 지각차이 분석

주민경,송선희 호서대학교 사회과학연구소 2012 社會科學硏究 Vol.31 No.1

한국어판 두통영향 검사(Headache Impact Test-6)의 타당도 및 신뢰도 조사

주민경,임형준,주영수,김주용,김윤중,유경호,마효일,이병철 대한신경과학회 2009 대한신경과학회지 Vol.27 No.1

Background: Quality-of-life measurement represents an important tool for evaluating the management and impact of headache on individuals and society. The Headache Impact Test-6 (HIT-6) is a simple instrument developed to assess headache-related disability in Western countries. The objective of this study was to determine the reliability and validity of the Korean HIT-6. Methods: Participants were recruited from patients who visited the Neurology Clinic of Hallym University Sacred Heart Hospital due to headache. The survey included the SF-36 and HIT-6. Headache diagnosis was assigned using ICHD-Ⅱ after completing a semistructured diagnostic interview. Results: A total of 43 patients were recruited, who were aged 35.2±13.6 years (mean±SD). Thirty-three and three were diagnosed as having migraine and probable migraine, respectively. Eight and two were diagnosed with tension-type and probable tension-type headache, respectively. There was a negative correlation between the total SF-36 and HIT-6 scores (Spearman’s correlation coefficient=-0.64, p<0.01). Similar significant negative correlations were also observed between SF-36 physical health summary and HIT-6 scores (Spearman’s correlation coefficient=-0.54, p<0.01), and between SF-36 mental summary and HIT-6 scores (Spearman’s correlation coefficient=-0.60, p<0.01). The Cronbach’s alpha of HIT-6 was 0.85. Conclusions: The Korean HIT-6 is a valid and reliable instrument for assessing headache-related quality of life. Background: Quality-of-life measurement represents an important tool for evaluating the management and impact of headache on individuals and society. The Headache Impact Test-6 (HIT-6) is a simple instrument developed to assess headache-related disability in Western countries. The objective of this study was to determine the reliability and validity of the Korean HIT-6. Methods: Participants were recruited from patients who visited the Neurology Clinic of Hallym University Sacred Heart Hospital due to headache. The survey included the SF-36 and HIT-6. Headache diagnosis was assigned using ICHD-Ⅱ after completing a semistructured diagnostic interview. Results: A total of 43 patients were recruited, who were aged 35.2±13.6 years (mean±SD). Thirty-three and three were diagnosed as having migraine and probable migraine, respectively. Eight and two were diagnosed with tension-type and probable tension-type headache, respectively. There was a negative correlation between the total SF-36 and HIT-6 scores (Spearman’s correlation coefficient=-0.64, p<0.01). Similar significant negative correlations were also observed between SF-36 physical health summary and HIT-6 scores (Spearman’s correlation coefficient=-0.54, p<0.01), and between SF-36 mental summary and HIT-6 scores (Spearman’s correlation coefficient=-0.60, p<0.01). The Cronbach’s alpha of HIT-6 was 0.85. Conclusions: The Korean HIT-6 is a valid and reliable instrument for assessing headache-related quality of life.

주야 교대 근무가 편두통에 미치는 영향 : 한림대학교 의료원 간호사 연구 Hallym Medical Center Nurse Study

주민경,유경호,마효일,김윤중,김주용,송흥기,이병철 대한두통연구회 2004 두통 Vol.5 No.1

불면증의 약물치료

주민경 대한수면연구학회 2006 Journal of sleep medicine Vol.3 No.1

Characterized by disorders of initiating or maintaining sleep, or nonrestorative sleep, insomnia is a prevalent condition that can coexist with psychiatric and medical illness and cause significant impairment of social and occupational functioning. Nonpharmacologic intervention in the treatment of insomnia includes behavioral and cognitive technique. Pharmacologic treatment should be considered for insomnia when the patient is significantly distressed by the presence of disturbed sleep or sleep disturbance is deleterious to the patient. Pharmacologic options include benzodiazepine receptor agonists, sedating antidepressants, antihistamines. The hypnotic drugs for insomnia should be carefully chosen, considering the characteristics of drugs and patients. The dose and treatment regimen for drug should be carefully and specifically prescribed and monitored by the physician.

Analysis of Dosage Mutation in PARK2 among Korean Patients with Early-Onset or Familial Parkinson’s Disease

주민경,김원찬,최정미,홍정훈,강석윤,마효일,김윤중 대한신경과학회 2014 Journal of Clinical Neurology Vol.10 No.3

Background and Purpose There is some controversy regarding heterozygous mutations ofthe gene encoding parkin (PARK2) as risk factors for Parkinson’s disease (PD), and all previousstudies have been performed in non-Asian populations. Dosage mutation of PARK2, rather thana point mutation or small insertion/deletion mutation, was reported to be a risk factor for familial PD; dosage mutation of PARK2 is common in Asian populations. Methods We performed a gene-dosage analysis of PARK2 using real-time polymerase chainreaction for 189 patients with early-onset PD or familial PD, and 191 control individuals. In thecase of PD patients with heterozygous gene-dosage mutation, we performed a sequencing analysis to exclude compound heterozygous mutations. The association between heterozygous mutation of PARK2 and PD was tested. Results We identified 22 PD patients with PARK2 mutations (11.6%). Five patients (2.6%)had compound heterozygous mutations, and 13 patients (6.9%) had a heterozygous mutation. The phase could not be determined in one patient. Three small sequence variations were foundin 30 mutated alleles (10.0%). Gene-dosage mutation accounted for 90% of all of the mutationsfound. The frequency of a heterozygous PARK2 gene-dosage mutation was higher in PD patientsthan in the controls. Conclusions Heterozygous gene-dosage mutation of PARK2 is a genetic risk factor for patients with early-onset or familial PD in Koreans.

Unusual trend of reverse thermal gelling poly (ethylene glycol)-DL-poly (alanine) diblock copolymers

주민경,박수현,정병문 한국고분자학회 2009 한국고분자학회 학술대회 연구논문 초록집 Vol.2009 No.10

경막하삼출물과 경막염증이 관찰된 미세다발혈관염 1예

주민경,민수기,유경호,마효일,김윤중,김주용,윤성희,김철호,이병철 대한신경과학회 2005 대한신경과학회지 Vol.23 No.6

Microcopic polyangiitis (MPA) is a systemic disorder affecting small vessels. In MPA, the central nervous system involvements have rarely been reported. We experienced a case of MPA with subdural effusion and pachymeningitis in a 50-year-old woman. The diagnosis of MPA was made by the presence of mononeuritis multiplex, hematuria, pachymeningitis, and p-ANCA seropositivity in this patient. Subdural effusion was of exudates and an active suppurative inflammation was observed on the dural biopsy.

Block Length Effect on the Aqueous solution properties of PEG poly

주민경,강은영,정병문 한국고분자학회 2010 한국고분자학회 학술대회 연구논문 초록집 Vol.2010 No.4

노인의 성인식이 삶의 만족도에 미치는 영향의 융복합적 연구

주민경,박경남 중소기업융합학회 2019 융합정보논문지 Vol.9 No.6

본 연구는 노인들의 성인식과 삶의 만족도 간의 관계를 분석하는데 그 목적이 있었다. 수원시와 그 주변에 거주하는 65세 이상인 노인들을 대상으로 설문조사를 하였으며, 총 256부를 자료 분석에 사용하였다. 연구결과는 다음과 같다. 첫째, 노인들의 성인식은 성생활 신념, 성생활 가치, 성생활 대화, 그리고 성생활 태도 등의 네 가지 하위 요인으로 나타났다. 둘째, 인구사회학적 특성에 따른 성인식과 삶의 만족도에는 일부 차이가 있었으며, 셋째, 노인의 삶의 만족도에 영향을 미치는 요인으로는 인구사회학적 특성에서는 배우자가 있는 경우, 건강상태와 경제상태가 좋을수록 노인의 삶의 만족도가 높게 나타났고, 성인식에서는 성생활대화가 많을수록 그리고 성생활태도가 높을수록 삶의 만족도가 높게 나타났다. 즉, 노 인의 성에 대한 인식의 교육의 활성화와 성교육 프로그램을 개발하여 실시할 필요가 있다. The purpose of this study was to analyze the relationships between sexuality recognition and life satisfaction of the elderly. 256 structured questionnaires were collected from the elderly who were 65 years old plus and live Suwon city and in the vicinity of this city. Findings of the study were as follows. First, the sexuality recognition of the elderly is composed of four(4) sub-variables such as Belief on sexuality, Value of Sexuality, Conversation on sexuality, and Attitude to sexuality. Second, some differences in sexuality recognition and satisfaction of the elderly according to the demographic factors of the sample were found. Third, in case of having spouse, being good health and economic status, and being high level of sexuality recognition variables such as conversation on sexuality and attitude to sexuality, the level of life satisfaction of the elderly were high. In other words, it is necessary to develop education program of sexual education to revitalize the education of the elderly 's awareness about sex.