메니에르병에서 내림프낭감압술 후 장기 추적관찰에 따른 치료 결과

서명환,김봉직,김종선 대한이비인후과학회 2008 대한이비인후과학회지 두경부외과학 Vol.51 No.4

The treatment result of endolymphatic sac decompression (ELSD) is controversial especially after a long term follow-up period. The aims of this study are to review the long term treatment outcome of ELSD and to analyze the factors associated with the long term prognosis. Subjects and Method:A retrospective review of medical records was performed. Sixteen patients (18 ears) who had been diagnosed with definite Ménière’s disease, had undergone ELSD and been followed up for more than 2 years were included in this study. The average follow up period was 88.6 months, with the range spanning from 25.7 to 243.4 months. All results were described according to the 1995 AAO-HNS criteria. Results:After a long term follow-up, vertigo was successfully controlled in 66.6% and hearing was preserved or improved in 58.8%. Tinnitus and aural fullness were relieved in 27.3% and 60.0% respectively. The preoperative hearing threshold (p=0.03) and caloric test (p=0.05) showed a close relationship with the long term vertigo control after ELSD. Conclusion:Although vertigo and hearing may deteriorate again after 2 years, ELSD generally seems to be able to control vertigo even after a long term follow up. Preoperative hearing threshold and caloric test may be able to serve as prognostic factors. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:319-25)

LCD 빔 프로젝터 사용 환경에서 가상 마우스 개발

徐明煥,崔祐榮 明知大學校 産業技術硏究所 2004 産業技術硏究所論文集 Vol.23 No.-

The usage of LCD beam projector is popular because of visualizing presentation data in connection with a computer and its various functions. In case of presentation, however, user's action is restricted by using mouse or remote controller. In this paper, PC-camera is used for more efficient usage of the beam projector and convenient user's action. We developed virtual mouse system composed of an convex mirror indicator and PC-camera. The dectected position of indicator is used for simulating vitual mouse function. Through the simulation, we can get the good result that the system works well with existing presentation software.

비정상적으로 높은 정현파회전검사 전정안반사 이득의 임상적 의의

서명환,김윤호,정재윤,이정구 대한이비인후과학회 2009 대한이비인후과학회지 두경부외과학 Vol.52 No.11

Background and Objectives The purpose of this study was to verify if high vestibulo-ocular reflex (VOR) gain in slow harmonic acceleration (SHA) test can be considered as a hallmark of a distinct disease entity. We hypothesized that patients with high VOR gain in the SHA test can be classified as a distinct disease group and looked for evidence that can support this hypothesis. Subjects and Method For this study, 306 patients who had undergone a rotation chair test were enrolled. We checked other VOR measurements (caloric test and step velocity) and clinical manifestation of the patients with high gain in SHA (HG group). The data were compared to those of the migraine associated vertigo (MAV), benign recurrent vertigo (BRV) and psychogenic dizziness (PsyD). Results An abnormally long time constant and a large response to the caloric test were found more frequently in the patient group with high gain in SHA. The incidence of high gain in SHA was significantly higher in MAV, BRV and PsyD. The clinical manifestation of HG group was not distinguishable from the effects of BRV and PsyD. But MAV was different from HG group. Conclusion We failed to find any evidence that the patients with high gain in the SHA could be classified as a distinct disease group. It seems that high gain is not merely a non-specific or incidental finding but a reproducible finding that reflects an aspect of the subject’s vestibular function. Also, the high gain in SHA is more suggestive of BRV or PsyD than MAV.

양측성 전정 기능 저하를 동반한 청신경병증

서명환,김지수,구자원 대한이비인후과학회 2006 대한이비인후과학회지 두경부외과학 Vol.49 No.5

Auditory neuropathy is a term used to describe the auditory neural pathway abnormality in the presence of cochlear outer hair cellfunctions. It is reported that 9 of 14 auditory neuropathy patients had abnormal findings in the caloric test. The authors present acase of auditory neuropathy accompanying bilateral vestibular loss. The patient was a 33-year-old female who had a familyhistory of her mother having bilateral hearing loss. Auditory brain stem response (ABR) and otoacoustic emission (OAE) werechecked and the results were compatible with auditory neuropathy. To evaluate her vestibular function, bithermal caloric test,rotatory chair, fundus photograph, vestibular evoked myogenic potential (VEMP), oculomotor test were checked. Laboratoryfindings were compatible with bilateral vestibular loss involving both superior and inferior division of vestibular nerve territory.Though bilateral vestibular hypofunction was substantial, she did not report any subjective discomfort from bilateral vestibularloss. Considering the presence of OAE and the abnormal findings in ABR in this patient, the pathologic lesion seems to be inthe vestibular neural pathway rather then in the vestibular end organs. Routine vestibular evaluation seems to be necessary forcomprehensive evaluation of the auditory neuropathy patients. (Korean J Otolaryngol 2006;49:488-93)

시스팀 통합과 멀티미디어 정보교환을 위한 아키텍처

서명환 한국경영정보학회 1992 한국경영정보학회 학술대회논문집 Vol.1992 No.-

비강과 사골동에 발생한 편평상피암종의 임상적 양상과 치료 결과

서명환,김시환,김용민,원태빈,이재서,이철희,민양기 대한이비인후과학회 2007 대한이비인후과학회지 두경부외과학 Vol.50 No.3

Background and Objectives:We aimed to evaluate the clinical manifestation and treatment outcome of the nasal cavity squamous cell carcinoma (SCC) and compared its survival rate with that of the maxillary sinus (MS) SCC. Subjects and Method: Thirty two patients who were diagnosed as nasal cavity SCC or ethmoid sinus SCC between 1984 and 2005 were selected. These patients were referred to as the intranasal (IN) SCC group. Ten prognostic factors were evaluated in terms of survival rate and recurrence. The survival rate of 61 patients who were diagnosed as MS SCC was compared with that of the IN SCC. Results:Chief complaints of the patients with IN SCC were nasal obstruction (40.4%), epistaxis (25.0%), and rhinorrhea (13.5%). The 5 year survival rate of IN SCC was 44.6% and the 5 year disease free survival rate was 27.7%. The most important prognostic factor was T stage (p<.001). The 5 year survival rate of MS SCC was 55.4%, and it was statistically not different from that of the IN SCC (p=.472). In the T1, T2, T3 stages, the 5-year-survival rate of the IN SCC was similar to that of MS SCC (p=.637). But in the T4 stage, IN SCC tended to have a worse prognosis (p=.074). Conclusion:The prognosis of IN SCC was similar to that of the MS SCC. However, MS SCCs were detected in a more advanced stage and T4 stage of the IN SCC had a worse prognosis compared to the same stage of MS SCC. (Korean J Otolaryngol 2007;50:215-9)

국내 동위원소(RI) 방사성폐기물의 육상운반 방사선영향평가

서명환,홍성욱,박진백 한국방사성폐기물학회 2015 한국방사성폐기물학회 학술논문요약집 Vol.13 No.2

의료영상 구역화 시스템 개발

徐明煥,崔祐榮 明知大學校 産業技術硏究所 2004 産業技術硏究所論文集 Vol.23 No.-

The purpose of this paper is to develop a semi-automated system for medical image processing with which tissues or organs from medical images can be segmented and classified by people who have basic knowledge of image processing. In addition, the proposed medical image processing system is independent on types of human tissues or images. In this paper, a new semi-automated image processing system with essential image processing functions for medical images is introduced

사용후핵연료 금속 겸용용기를 활용한 저장시설 개념모델에 대한 방사선환경영향평가

서명환,김태만,백창열,차길용 대한방사선방어학회 2012 대한방사선방어학회 학술발표회 논문요약집 Vol.2012 No.11

Clinical Manifestations of Recurrent Parotid Pleomorphic Adenoma

서명환,권성근,김광현,성명훈,하정훈,정영호,권택균 대한이비인후과학회 2009 Clinical and Experimental Otorhinolaryngology Vol.2 No.4

Objectives. This study was undertaken to confirm the clinical characteristics of recurrent pleomorphic adenoma (RPA), and to identify those factors that affect the development of malignant transformation (MT) from RPA. Methods. The medical records of 270 patients, who were operated upon for parotid PA, were retrospectively reviewed. The pathologic specimens of a selected series of 23 patients were reviewed for histologic subtype and microscopic multi-nodularity. Results. Mean age of initial operation in RPA without MT (RPA-MT) group was significantly lower than that of primary PA group. Mean age of the revision operation in RPA with MT (RPA+MT) group was significantly greater than that of RPA-MT group. Mean interval from operation to recurrence shortened after each revision operation. The risk of MT and additional recurrence increased significantly with recurrence. In RPA-MT group tumor recurrence occurred in 21.4% of patients despite a clear resection margin. Conclusion. The risk factors for MT may be an age of over 45 yr and multiple recurrences. However, younger patients are more at risk of recurrence. A clear resection margin cannot guarantee a cure in RPA, and it seems that parotid pleomorphic adenomas slowly gain malignant characteristics after repeated recurrences. Objectives. This study was undertaken to confirm the clinical characteristics of recurrent pleomorphic adenoma (RPA), and to identify those factors that affect the development of malignant transformation (MT) from RPA. Methods. The medical records of 270 patients, who were operated upon for parotid PA, were retrospectively reviewed. The pathologic specimens of a selected series of 23 patients were reviewed for histologic subtype and microscopic multi-nodularity. Results. Mean age of initial operation in RPA without MT (RPA-MT) group was significantly lower than that of primary PA group. Mean age of the revision operation in RPA with MT (RPA+MT) group was significantly greater than that of RPA-MT group. Mean interval from operation to recurrence shortened after each revision operation. The risk of MT and additional recurrence increased significantly with recurrence. In RPA-MT group tumor recurrence occurred in 21.4% of patients despite a clear resection margin. Conclusion. The risk factors for MT may be an age of over 45 yr and multiple recurrences. However, younger patients are more at risk of recurrence. A clear resection margin cannot guarantee a cure in RPA, and it seems that parotid pleomorphic adenomas slowly gain malignant characteristics after repeated recurrences.