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3대에 걸쳐서 나타난 유전적 (遺傳的) 대측성 (對側性) 색소이상증
전인기,김영표 대한피부과학회 1970 大韓皮膚科學會誌 Vol.8 No.1
Dyschromatosis Symmetrica Hereditaria (Toyama) is one of the pigment anormaly hereditary skin disease which is known to manifest the Japanese. Various authors such as Toyama, Matsumoto, Komaya-Dohi and Ichikawa-Hiraga have reported the disease under different diagnostic name. Clinical characteristics of the disease are shown to have multiple reticular dark brown spotty macular skin lesion mostly over the face, neck, back of hands, feet, fingers and toes, which are affecting symmetrically, without subjective symptom, and occasionally the pigmented and depigmented macular lesions are intermingled. Among these author's reports to the disease, one postulate those which Matsumoto and Komaya-Dohi's cases were essentially similar type in clinical manifestation and were described as showing spotty pigmented macules intermingling with the depigmented over the areas as those of Toyama's. In this article, a case of Dyschromatosis Symemtrica Hereditaria manifesting 21 years old Korean male, which is similar to Matsumoto's type, is presented. Search for the heredity back ground revealed that the grandfather and mother were affected by this disease, and authors assumed the types of heredity of the disease to be irregular non-sexlinked dominant inheritance. Authors presented also distinctions of the histopathological findings of the disease which are hyperkeratosis, increased melanin granules in stratum mucosum layer and imperfect or immatured granular cells, and discussions of differential diagnosis and review of literatures are made.
수종의 바이러스성 피부질환 치료에 대한 바이라미드(Viramid®)연고의 임상효과에 관한 이중맹검 연구
전인기,이선화,노병인,장진요,신용우,임경진 中央醫學社 1983 中央醫學 Vol.45 No.6
We performed a double blind study to evaluate the therapeutic effect of Viramid® ointment on the several viral skin diseases. Totally 106 patients including 37 herpes patients (herpes labialis; 17 patients, herpes progenitalis; 8 patients, and other form of herpes simplex; 12 patients), 38 herpes zoster patients, and 31 varicella patients were studied by topical application of Viramid® ointment (experimental group) or placebo ointment (control group) on the early lesion of each diseases. The estimation of therapeutic effect of Viramid® ointment was done by -the- meas urement of time interval from the first day of treatment to the day of crust formation. The results were as follows: 1) Herpes simplex; In the experimental group, the percentage of herpes labialis patients who showed crust formation within the second day of treatment was -40.0 %. The percentage of herpes progenitalis patients and other form of herpes simplex patients were 12.5% and 18.2% respectively. In the control group, the percentage of herpes labialis, herpes progenitalis, and other form of herpes simplex patients who showed crust formation ;within the second day of treatment were 12.5%, 0%, and 0%, respectively. All of 3. experimental groups showed shorter time of crust formation than those of control groups. 2) Herpes zoster; In the experimental group, the percentage of herpes zoster patients who showed crust formation within the 4th day of treatment was 75.8%, but those of control group was 25.0%. The time of crust formation of experimental group was shorter than those of control group. 3) Varicella; In the experimental group, the percentage of varicella patients who- showed crust formation within the second day of treatment was 43.5% and those of control group was 23.1%. The time of crust formation of experimental group was shorter than those of control group.