Antiadhesive effect and safety of oxidized regenerated cellulose after thyroidectomy

Kyoung Sik Park,Kyu Eun Lee,Do Hoon Ku,Su-Jin Kim,Won Seo Park2,Hoon Yub Kim3,,Mi Ra Kwon1,Yeo-Kyu Youn1 대한외과학회 2013 Annals of Surgical Treatment and Research(ASRT) Vol.84 No.6

Purpose: To evaluate the antiadhesive effects and safety of an oxidized regenerated cellulose (Interceed) after thyroidectomy. Methods: Seventy-six thyroidectomized patients were prospectively randomized into two groups with regard to the use of Interceed. We evaluated each group for their adhesive symptoms using four subjective and four objective items at the 2nd week, 3rd and 6th month after thyroidectomy. All patients were examined for vocal cord motility by indirect laryngoscope at each period. Results: Total adhesion scores at each postoperative follow-up period decreased with time, but were not significantly different in each group. The median score for swallowing discomfort for liquid was significantly lower in the Interceed group than in the control group 2 weeks after surgery. In addition, the severity of skin adhesion to the trachea was reduced in the Interceed group compared with the control group 6 months after surgery. During the study, there were no adverse effects or significant differences in postoperative complications between the groups. Conclusion: Interceed appeared to be safe and effective in improving neck discomfort at early postoperative periods and preventing skin adhesion to the trachea 6 months after thyroidectomy.

Simulated resin root canal에서 엔진 구동형 Ni-Ti 파일로 근관성형 후 Buchanan plugger의 근관 내 삽입깊이에 대한 비교 연구

박연식,김동준,황윤찬,황인남,오원만 大韓齒科保存學會 2006 Restorative Dentistry & Endodontics Vol.31 No.2

본 연구는 레진 블록에서 엔진구동형 Ni-Ti 기구를 이용하여 근관성형 후 Buchanan plugger의 삽입 깊이에 대한 비교를 통해 임상적 상황에서 Ni-Ti 파일로 근관 성형 후 Continuous wave of condensation technique을 이용한 근관 충전시 적절한 크기의 Buchanan plugger 선택에 지침을 제공하기 위해 시행되었다. 만곡근관과 직선근관을 가진 레진 블록에서 ProTaper와 ProFile을 이용하여 근관 성형을 하였다. 성형 후 근관에 Buchanan plugger 가 근관벽과 처음으로 접촉하는 부위까지 삽입한 후 그 상태에서 스태너를 이용하여 이미지를 얻었다. 이미지 분석 프로그램을 이용해 근첨에서 plugger 첨부까지의 거리를 얻었다. 각 기구에 대한 plugger 삽입깊이에 대한 유의성을 검정하기 위해 one-way ANOVA를 시행하였고, 사후검정을 위해 Scheffe's test를 시행하였다. 본 연구의 결과 만곡되고 좁읍 근관에서, ProTaper F2와 F3로 마무리 성형한 근관에서 F. FM 크기의 plugger를 사용할 경우 Continuous wave of condensation technique으로 적절한 근관충전이 가능함을 시사하였다. This study was conducted to evaluate the insertion depth of Buchanan plugger after shaping by various Ni-Ti rotary files. It was conducted to determine which size of plugger are appropriate, when root canals are shaped with Ni-Ti rotary files and obturated by Continuous wave of condensation technique. Two type of eighty simulated resin blocks were used : J-shaped and straight shaped canal. The simulated canals were instrumented by ProTaper and ProFile. Buchanan pluggers were inserted into the canal, and then the image was recorded to scanner. The distance from the apex of the canal to the plugger tip was measured by image analysis program. Data were analyzed by one-way ANOVA followed by Scheffe's test. The results were as follows 1. In straight canal finished up to ProTaper F2 and F3 file, F and FM pluggers were inserted more than 5 ㎜ short of working length. 2. In J-shaped canal finished up to ProTaper F2 file, F pluggers were inserted more than 5 ㎜ short of working length. Finished up to ProTaper F3 file, F and FM pluggers were inserted more than 5 ㎜ short of working length. 3. In straight and J-shaped canal finished up to ProFile . 06/#20 and ,06/#25, any of Buchanan plugger could not be inserted more than 5 ㎜ short of working lenghth. These results suggest that canals shaped by ProTaper could be obturated by Continuous wave of condensation technique with F and FM size Buchanan plugger.

형질전환 담배 식물체에서 개똥쑥 Terpene Synthase의 발현

박성길,홍성현,최근원,이윤형,정인식 경희대학교 생명자원과학연구원 2002 硏究論文集 Vol.22 No.-

Expression of Artemisia annua terpene synthase in transgenic tobacco plants was examined. A full length cDNA encoding terpene synthase was cloned into pILTAB357 vector and transgenic tobacco plants were generated. The integration of this gene was analyzed by genomic DNA PCR and Southern blot analysis. The transcription of the terpene synthase gene in tobacco was confirmed by RT-PCR and northern blot analysis.

前腕部 經穴 取穴에서 骨度分寸法과 一夫法의 比較 硏究

박히준,채윤병,차웅석,박종배,이혜정,이향숙,인창식,고형균,김수영,최일환,김강식,문정배,배기태,유경환,육근영,정병주,손인철,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Background : The cun measurement System, an essential and convenient method in locating acupoints, has been widely used in the practice of acupuncture. However, traditional cun measurement has been criticized for its lack of reliability. Objectives : The purposes of this study are to determine if one cun measured by the directional methods have a consistency with that of proportional methods and to investigate which factors are related with these differences, especially in forearm. Methods : The distance between the elbow crease and the wrist crease of forearm was compared to a reference value of one cun obtained by the directional method. In this method, one cun is one third of the distance between index finger and Small finger of a subject, measured at proximal interphalangeal joint. In addition, to investigate the factors influencing the differences between these two methods, we measured the height and body weight and calculated body mass index (BMI). Finally we analyzed the factors correlated with these lengths by linear regression test. Results : The results showed that one cun obtained by the directional methods were significantly different from one cun by the proportional methods in forearm. It was demonstrated that the length acquired with the directional method was more correlated with body weight and body mass index, while the length obtained by the proportional method was more correlated with the height.

유전체로 둘러싸인 속빈 직육면체 도파관을 사용한 레이저 공진기에서 횡특성모드의 왕복손실

金允溟,金永植,李鍾旿,徐七成,박재우 단국대학교 1989 論文集 Vol.23 No.-

The round-trip losses of CO_2 laser wavelength in a hollow rectangular dielectric waveguide with external spherical mirrors are calculated. The propagative attenuations of some higher order modes with different polarization are analyzed as well as EH_11 fundamental mode. Computations of the losses in coupling radiation of various modes from the guide into free space and back into the guide, as a function of mirror curvature and position, are also presented. The overall return losses of various modes are the sum of the two kinds of losses.

Bruner의 敎育理論의 槪括的 考察

全閏植,朴榮煥 부산대학교 1972 論文集 Vol.14 No.1

Jeromes Bruner's learning theory is considered to have come from a challenge of Russian scientific deveopment (Sputnic) and accordingly re-evaluation of John Dewey's theory. The writers reviewed the backgrounds, theorotical foundation and the limits of his theory in comparison with those of John Dewey's theory. Dewey emphasized empiricism on the foundation of pragmatism, while Bruner based his theory on the structure of knowledge from the standpoint of realism, especially neo-realism. Bruner regards knowledge as close inquiry of entity which lies in the object of study, but Dewey think knowledge as a result of learning by doing. Bruner viewed an instruction on the basis of learning about learning. He also insits on a branch curriculum or a spiral curriculum. He is confident of the unnecessity of readiness basing on the theory of Piaget's child development. He claims intrinsic motivation and transfer by structure in stead of traditional, extrinsic compensation in learning situation. There are a lots of points to be noted in his theory, but due consideration must be given before it is accepted in this society.

치근단 실험병소에 대한 골주사 및 방사선학적 연구

임윤식,박태원 大韓口腔顎顔面 放射線學會 1989 Imaging Science in Dentistry Vol.19 No.1

The purpose of this study was to clarify that scintigram was a more effective method than radiogram in the early detection of periapical lesion. Periapical lesions were produced artificially by the opening of the pulp chambers of the lower right 3rd and 4th premolars in 6 dogs. The serial bone scintigrams using 99m-Tc-MDP and periapical radiograms were taken weekly. The uptake counts of the 99-Tc-MDP in the experimental side were compared with those in the control side. The periapical radiograms were interpreted with the joint evaluation by three dental radiologists. The following results were obtained; 1. The radioactivity in the experimental side was increased at the 1st week except one animal in which the radioactivity was increased at the 2nd week. 2. It was observed that increasing amount of radioactivity per week was prominent from the 1st day of experiment to the 1st week, and the 3rd week to the 4th week. 3. The radiographic evidence of the periapical lesions was observed at the 3rd week and became more apparent at the 4th week. 4. Histologically, proliferation of blood vessels and infiltration of chronic inflammatory cells were observed at the 1st week and osteoblasts were found after the 3rd week.

레이저 계측에 의한 맞대기 용접부의 스트레인 측정

성백섭,차용훈,박창언,김일수,김덕중,이연신,손준식 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

Currently knowledge of strain in welds has mainly been obtained from strain gaging method; that is directly attaching most of the material to the gage. The very few non-contact method are still in the early stage. One of the non-contact methods is by the use of the laser that has high-level of the accuracy for the measurement, and this laser also has excellent characteristics on which many studies for its applications are focused throughout the many fields. The dissertation is on the measurement of the strain caused by the characteristics and the temperature changes of the TIG welded zone which is used with 3D ESPI system that is functionally modified through the laser ESPI system. This system employed the aluminum sheet-metal which are mainly used for the steel plate such as for the electronics, chemistry, food instrument and electronic appliances.

Elevated TRAF2/6 expression in Parkinson's disease is caused by the loss of Parkin E3 ligase activity.

Chung, Ji-Yun,Park, Hee Ra,Lee, Su-Jin,Lee, Sun-Hye,Kim, Jin Sik,Jung, Youn-Sang,Hwang, Sang Hyun,Ha, Nam-Chul,Seol, Won-Gi,Lee, Jaewon,Park, Bum-Joon United States and Canadian Academy of Pathology [e 2013 Laboratory investigation Vol.93 No.6

<P>Parkinson's disease (PD) is the second leading neurodegenerative disease, and is known to be induced by environmental factors or genetic mutations. Among the verified genetic mutations of PD, Parkin, isolated from the PARK2 locus, shows an autosomal recessive inheritance pattern and is known to be an E3 ligase. However, the physiological target of Parkin and the molecular mechanism of Parkin-deficiency-induced PD have not been clearly demonstrated until now. It has recently been proposed that inflammation, suggesting as a causal factor for PD, is enhanced by Parkin deficiency. Thus, we examined the relationship between inflammation-related factors and Parkin. Here, we provide the evidence that Parkin suppresses inflammation and cytokine-induced cell death by promoting the proteasomal degradation of TRAF2/6 (TNF-α receptor-associated factor 2/6). Overexpression of Parkin can reduce the half-lives of TRAF2 and TRAF6, whereas si-Parkin can extend them. However, mutant Parkins did not alter the expression of TRAF2/6. Thus, loss of Parkin enhances sensitivity to TNF-α- or IL-1β-induced JNK activation and NF-κB activation. Indeed, si-Parkin-induced apoptosis is suppressed by the knockdown of TRAF6 or TRAF2. We also observed elevated expression levels of TRAF6 and a reduction of IκB in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced PD mouse model. Moreover, elevated expression levels or aggregation of TRAF6 were detected in approximately half of the human PD tissues (7/15 cases) and 2 cases, respectively. In addition, TRAF6 and Parkin expression levels show a reverse relationship in human PD tissues. Our results strongly suggest that the reduction of Parkin or overexpression of TRAF2/6 by chronic inflammation would be the reason for occurrence of PD.</P>

용접판재의 피로강도에 미치는 잔류응력 평가

차용훈,김덕중,이연신,채경수,성백섭,박회식 조선대학교 동력자원연구소 1997 動力資源硏究所誌 Vol.19 No.1

The objective of this thesis is to investigate the influence of the initial residual stress on the fatigue crack growth after the distribution of the initial residual stress is measured when the crack is growing from the compressive residual stress to the tensile residual stress field. In the case of as welded material, respective of load ratio, the span of the fatigue is the shortest in base metal, while in weld metal and HAZ, the crack growth was retarded due to the effect of the compressive residual stress at the crack tip as well as the span of the crack is longer than base metal. In region II that is in stable growth state of the fatigue crack, da/dN=C(ΔK)^m of power law was satisfied. Also, it was considered that the value of m is not affected by residual stress. Superimposing welding residual stress intensity factor K_res on ΔK, the value of ΔK_eff calculated was lower than ΔK in the same value of da/dN, while the ΔK_eff is almost the same at the high ΔK.