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      • KCI등재

        Assessment Method of Slope Excavation Quality based on Point Cloud Data

        Zhiguo Pan,Yihong Zhou,Chunju Zhao,Chao Hu,Huawei Zhou,Yong Fan 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.3

        Slope excavation quality assessment is essential in water conservancy engineering. This study presents a quality assessment method to estimate the excavation quality of a slope based on point cloud data obtained from a 3D Terrestrial Laser Scanner (TLS). A data processing method, which includes coordinate registration, data partitioning, and noise removal, is proposed to organize raw data from the TLS and ensure accurate and available point cloud data of a slope surface. An excavation quality assessment method with seven indicators, namely, slope ratio, slope toe elevation, back break, volume of back break, remained semi-void rate, unevenness, and offset degree, is proposed to analyze the difference between a slope’s as-design excavation appearance and actual construction appearance. The as-design excavation appearance is expressed by the Building Information Modeling (BIM) model of a slope-excavation face, and it is a reference to assess the actual construction appearance. The slope excavation quality of a water conservancy project in southwest China is evaluated with the proposed method and the traditional method. The results demonstratethat the proposed method can estimate the slope excavation quality effectively, rapidly, and accuately, and can provide theoretical data support for subsequent work.

      • KCI등재

        Temperature Field Reconstruction of Concrete Dams based on Distributed Optical Fiber Monitoring Data

        Huawei Zhou,Zhiguo Pan,Zhipeng Liang,Chunju Zhao,Yihong Zhou,Fang Wang 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.5

        Mastering the real temperature distribution of the concrete dam is the basis for solving the problem of temperature control and crack prevention. In this paper, Distributed Temperature Sensing (DTS) technology was applied to temperature monitoring of a higharch dam under construction in southwest China. In order to obtain a more comprehensive temperature distribution of the dam, optical fiber layout principles for arch dams were studied, and horizontal and vertical optical fiber layout schemes were first proposed according to these principles. The real temperature variation processes of the dam were obtained in real time with a line temperature measurement pattern instead of a point temperature measurement pattern. Additionally, a framework of distributed optical fiber data acquisition and remote transmission was proposed. Interconnection of multiple DTS hosts and remote transmission of temperature data were realized. Then, two-dimensional temperature fields of a typical dam block in different ages and longitudinal profiles of dam blocks with embedded fibers were reconstructed based on large amounts of temperature monitoring data and the Kriging difference algorithm. Temperature field reconstruction results showed that the temperature distribution law of the concrete arch dam was in accordance with the actual situation.

      • KCI등재

        In Vitro and In Vivo Study on the Effect of Lysosome-associated Protein Transmembrane 4 Beta on the Progression of Breast Cancer

        Deyou Tao,Junqing Liang,Yihong Pan,Yanting Zhou,Ying Feng,Lin Zhang,Jingjing Xu,Hui Wang,Ping He,Jie Yao,Yang Zhao,Qinjie Ning,Wen Wang,Wei Jiang,Jing Zheng,Xia Wu 한국유방암학회 2019 Journal of breast cancer Vol.22 No.3

        Purpose: Although the effect of lysosome-associated protein transmembrane 4 beta (LAPTM4B) on the proliferation, migration, and invasion of breast cancer (BC) cells has already been studied, its specific role in BC progression is still elusive. Here, we evaluated the effect of different levels of LAPTM4B expression on the proliferation, invasion, adhesion, and tumor formation abilities of BC cells in vitro, as well as on breast tumor progression in vivo. Methods: We investigated the influence of LAPTM4B expression on MCF-7 cell proliferation, invasion, adhesion, and tube formation abilities in vitro through its overexpression or knockdown and on breast tumor progression in vivo. Results: Cell growth curves and colony formation assays showed that LAPTM4B promoted the proliferation of breast tumor cells. Cell cycle analysis results revealed that LAPTM4B promoted the entry of cells from the G1 into the S phase. Transwell invasion and cell extracellular matrix adhesion assays showed that LAPTM4B overexpression increased the invasion and adhesion capabilities of MCF-7 cells. More branches were observed in MCF-7 cells overexpressing LAPTM4B under an electron microscope. In comparison with LAPTM4B overexpression, LAPTM4B knockdown decreased the expression of vascular endothelial growth factor-A and significantly inhibited the vasculogenic tube formation ability of tumors. These results were also verified with western blot analysis. Conclusion: LAPTM4B promoted the proliferation of MCF-7 cells through the downregulation of p21 (WAF1/CIP1) and caspase-3, and induced cell invasion, adhesion, and angiogenesis through the upregulation of hypoxia-inducible factor 1 alpha, matrix metalloproteinase 2 (MMP2), and MMP9 expression. This specific role deems LAPTM4B as a potential therapeutic target for BC treatment.

      • SCIESCOPUSKCI등재

        Characterization of Microbial Communities in Chinese Rice Wine Collected at Yichang City and Suzhou City in China

        ( Yucai Lu ),( Yanli Gong ),( Yajie Li ),( Zejing Pan ),( Yi Yao ),( Ning Li ),( Jinling Guo ),( Dachun Gong ),( Yihong Tian ),( Caiyun Peng ) 한국미생물생명공학회(구 한국산업미생물학회) 2017 Journal of microbiology and biotechnology Vol.27 No.8

        Two typical microbial communities from Chinese rice wine fermentation collected in Yichang city and Suzhou city in China were investigated. Both communities could ferment glutinous rice to rice wine in 2 days. The sugar and ethanol contents were 198.67 and 14.47 mg/g, respectively, for rice wine from Yichang city, and 292.50 and 12.31 mg/g, respectively, for rice wine from Suzhou city. Acetic acid and lactic acid were the most abundant organic acids. Abundant fungi and bacteria were detected in both communities by high-throughput sequencing. Saccharomycopsis fibuligera and Rhizopus oryzae were the dominant fungi in rice wine from Suzhou city, compared with R. oryzae, Wickerhamomyces anomalus, Saccharomyces cerevisiae, Mucor indicus, and Rhizopus microsporus in rice wine from Yichang city. Bacterial diversity was greater than fungal diversity in both communities. Citrobacter was the most abundant genus. Furthermore, Exiguobacterium, Aeromonas, Acinetobacter, Pseudomonas, Enterobacter, Bacillus, and Lactococcus were highly abundant in both communities.

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