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THE EVOLUTION OF STAR FORMATION HISTORIES OF QUIESCENT GALAXIES
Pacifici, Camilla,Kassin, Susan A.,Weiner, Benjamin J.,Holden, Bradford,Gardner, Jonathan P.,Faber, Sandra M.,Ferguson, Henry C.,Koo, David C.,Primack, Joel R.,Bell, Eric F.,Dekel, Avishai,Gawiser, Er American Astronomical Society 2016 The Astrophysical Journal Vol.832 No.1
<P>Although there has been much progress in understanding how galaxies evolve, we still do not understand how and when they stop forming stars and become quiescent. We address this by applying our galaxy spectral energy distribution models, which incorporate physically motivated star formation histories (SFHs) from cosmological simulations, to a sample of quiescent galaxies at 0.2 < z < 2.1. A total of 845 quiescent galaxies with multi-band photometry spanning rest-frame ultraviolet through near-infrared wavelengths are selected from the Cosmic Assembly Near-IR Deep Extragalactic Legacy Survey (CANDELS) data set. We compute median SFHs of these galaxies in bins of stellar mass and redshift. At all redshifts and stellar masses, the median SFHs rise, reach a peak, and then decline to reach quiescence. At high redshift, we find that the rise and decline are fast, as expected, because the universe is young. At low redshift, the duration of these phases depends strongly on stellar mass. Low-mass galaxies (log(M*/M-circle dot) similar to 9.5) grow on average slowly, take a long time to reach their peak of star formation (greater than or similar to 4 Gyr), and then the declining phase is fast (less than or similar to 2 Gyr). Conversely, high-mass galaxies (log(M*/M-circle dot) similar to 11) grow on average fast (less than or similar to 2 Gyr), and, after reaching their peak, decrease the star formation slowly (greater than or similar to 3). These findings are consistent with galaxy stellar mass being a driving factor in determining how evolved galaxies are, with high-mass galaxies being the most evolved at any time (i.e., downsizing). The different durations we observe in the declining phases also suggest that low- and high-mass galaxies experience different quenching mechanisms, which operate on different timescales.</P>
Identification of new SLE-associated genes with a two-step Bayesian study design
Armstrong, D L,Reiff, A,Myones, B L,Quismorio Jr, F P,Klein-Gitelman, M,McCurdy, D,Wagner-Weiner, L,Silverman, E,Ojwang, J O,Kaufman, K M,Kelly, J A,Merrill, J T,Harley, J B,Bae, S-C,Vyse, T J,Gilkeso Macmillan Publishers Limited 2009 GENES AND IMMUNITY Vol.10 No.5
In our earlier study, we utilized a Bayesian design to probe the association of ∼1000 genes (∼10 000 single-nucleotide polymorphisms (SNPs)) with systemic lupus erythematosus (SLE) on a moderate number of trios of parents and children with SLE. Two genes associated with SLE, with a multitest-corrected false discovery rate (FDR) of <0.05, were identified, and a number of noteworthy genes with FDR of <0.8 were also found, pointing out a future direction for the study. In this report, using a large population of controls and adult- or childhood-onset SLE cases, we have extended the earlier investigation to explore the SLE association of 10 of these noteworthy genes (109 SNPs). We have found that seven of these genes exhibit a significant (FDR<0.05) association with SLE, both confirming some genes that have earlier been found to be associated with SLE (PTPN22 and IRF5) and presenting novel findings of genes (KLRG1, interleukin-16, protein tyrosine phosphatase receptor type T, toll-like receptor (TLR)8 and CASP10), which have not been reported earlier. The results signify that the two-step candidate pathway design is an efficient way to study the genetic foundations of complex diseases. Furthermore, the novel genes identified in this study point to new directions in both the diagnosis and the eventual treatment of this debilitating disease.Genes and Immunity (2009) 10, 446–456; doi:10.1038/gene.2009.38; published online 14 May 2009
Four-user 10-Gb/s spectrally phase-coded O-CDMA system operating at /spl sim/30 fJ/bit
Zhi Jiang,Dongsun Seo,Shangda Yang,Leaird, D.E.,Roussev, R.V.,Langrock, C.,Fejer, M.M.,Weiner, A.M. IEEE 2005 Photonics Technology Letters Vol.17 No.3
<P>We demonstrate a four-user 10-Gb/s spectrally phase-coded optical code-division multiple-access system via nonlinear processing with ultralow power (/spl sim/30 fJ/bit). Full interference suppression is achieved in a time-slotted scheme without the need for chip-level coordination and synchronous detection. Performance degradation caused by pulse overlap between users is investigated.</P>
Reconfigurable all-optical code translation in spectrally phase-coded O-CDMA
Jiang, Z.,Seo, D.S.,Leaird, D.E.,Roussev, R.V.,Langrock, C.,Fejer, M.M.,Weiner, A.M. IEEE 2005 Journal of Lightwave Technology Vol.23 No.6
Reconfigurable all-optical code translation are demonstrated in a spectrally phase-coded optical-code-division multiple-access (O-CDMA) testbed with an interference user. For both one-stage and two-stage code translations, less than 0.9-dB power penalties are induced at each code translation. Multistage code translations are investigated via simulation and experimental emulation in a loop pulse shaper to show the potential application of the proposed method for up to several tens of code translations.
Spectral line-by-line pulse shaping.
Jiang, Z,Seo, D S,Leaird, D E,Weiner, A M Optical Society of America 2005 Optics letters Vol.30 No.12
<P>We experimentally demonstrate pulse-shaping experiments in which the individual spectral lines that are present in the output of a mode-locked laser (8.5 GHz mode spacing, centered at 1542 nm) are resolved. The shaped pulses overlap in time, and this leads to a new way to observe fluctuations of the comb-offset frequency in the time domain.</P>