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- 저자 : Wang Chengsheng (검색결과 3 건)
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Investigation on Large Power AC Drive System
Chengsheng Wang,Chongjian Li,Li Li,Chunyi Zhu,Zhiming Lan 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5
The performance of the large power AC drive system for rolling mills should meet the need of production technology and adapt to the requirement of the electric network. In the paper, the cycloconverter system is introduced. With the development of large power electronics, application of the large power converter using the self-controllable devices such as IGCT becomes the trend. The three-level AC-DC-AC converter system with IGCTs whose rated power is 16MVA has been developed and put into use. And it is estimated that the AC-DC-AC converter system will be used in the drive for rolling mills in the near future.
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Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers
Cho Sung-Yup,오유미,Jeong Eui Man,박상희,Dakeun Lee,Xiaorui Wang,Qiqi Zeng,Hongyu Qin,Fang Hu,Hui Gong,Xi Liu,Guanjun Zhang,나득채,이지은,채지수,서윤석,공성호,Hyuk-Joon Lee,Jong-Il Kim,박한수,Chengsheng Zhang,양한광,Charles Lee 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-
Tumor-promoting inflammation is a hallmark of cancer and is highly associated with tumor progression, angiogenesis, and metastasis. Tumor-associated macrophages (TAMs) are major drivers of tumor-promoting inflammation, but due to the complexity of the tumor microenvironment, the detailed regulatory mechanisms are still under investigation. Here, we investigated a novel role for transglutaminase 2 (TGM2) in the development of tumor-promoting inflammation and recruitment of TAMs to gastric cancer (GC) tissues. When estimated by array comparative genomic hybridization and droplet digital PCR, the copy numbers of the TGM2 gene were amplified in 13.6% (14/103) of GC patients and positively associated with TGM2 expression. Gene set enrichment analysis of expression microarray data for GC samples with high or low TGM2 expression showed that increased TGM2 expression was associated with tumor-promoting inflammation in GC. In addition, the expression of TGM2 was correlated with the expression of markers for macrophages, neutrophils, blood vessels, and lymphatic vessels. Overexpression of TGM2 in GC cells augmented the IL-1β-induced secretion of macrophage-recruiting chemokines and NF-κB activation. TGM2 protein levels were associated with the expression levels of the macrophage marker CD163 in human GC tissue samples. Moreover, GC patients with high expression of TGM2 had a worse prognosis than those with low expression of TGM2. These results suggest TGM2 as a novel regulator of the tumor microenvironment of GC and provide a promising target for constraining tumor-promoting inflammation.
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The Development of IGCT-based Large Capacity Three-Level Dual-PWM Converter
Lan Zhiming,Li Chongjian,Li Yaohua,Zhu Chunyi,Wang Chengsheng 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5
In media and high voltage large capacity converter systems the Integrated Gate Commutated Thyristor (IGCT) take the place of Gate Turn Off Thyristor (GTO) duo to its outstanding performance. And IGCT-based large capacity three-level converters are widely used in industrial motor-driving field. In this paper the development of a set of IGCT-based large capacity three-level dual-PWM converter is introduced. The converter includes PWM rectifier, DC capacitors, PWM inverter. The topology of the converter is given. The close-loop control strategy and SVPWM algorithm of PWM rectifier is presented in this paper. The control strategy and algorithm of the PWM inverter is also presented. The experiments were performed and the results show that the converter reaches the design requirement and has excellent performance.
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