人工水路에서 模型實驗에 의한 開水路흐름의 水理特性解析 : Ⅱ. 移動床 解析

池洪基,李舜鐸,金成原 嶺南大學校 工業技術硏究所 1997 工業技術硏究所論文集 Vol.25 No.2

In this study, movable bed model testing was carried out in order to analyze bed profile changes and to predict scouring and deposition of bed profile and to hydraulic problems affecting with bed and both-bank between upstream and downstream of intake weir in the study channel. the movable bed model testing consists of fundamental test, numerical analysis test and movable model test, the fundamental test is enforced to analyze relationship of discharge and sediment load in the tilting flume, in order to complement unsolving hard problems during movable model test, numerical analysis test is operated, by I-dimensional bed profile changes model ; HEC-6 model, while the movable model test is operated it is represented for sediment budget to balance exactly between input sediment load and output sediment load, as a result of movable model test, it is presented that scouring and deposition changes in quantities between the upstream and downstream of modification weir were less than those of nature and planning weir. therefore, modification weir will be sustained the stable bed profile changes than any other weirs in the study channel.

Optimization Algorithms for a Car Re-sequencing Problem in Automotive Paint Shops

Sungwon Hong(홍성원),Jinil Han(한진일),Kyungsik Lee(이경식) 대한산업공학회 2016 대한산업공학회 춘계학술대회논문집 Vol.2016 No.4

Accelerated dynamic programming algorithms for a car resequencing problem in automotive paint shops

Hong, Sungwon,Han, Jinil,Choi, Jin Young,Lee, Kyungsik Elsevier 2018 Applied mathematical modelling Vol.64 No.-

<P><B>Abstract</B></P> <P>In this paper, a car resequencing problem (CRP) for automotive paint shops is considered, whereby a set of cars conveyed from an upstream shop to one of the multiple conveyors is retrieved sequentially before the painting operation. The aim of the CRP is to find a car retrieval sequence that minimizes the sequence-dependent changeover cost, which is the cost that is incurred when two consecutive cars do not share the same color. For this problem, we propose accelerated dynamic programming (ADP) algorithms that utilize strong combinatorial lower bounds and effective upper bounds in a standard dynamic programming framework, thus outperforming existing exact algorithms. Testing of our algorithms over a wide range of instances confirmed that they are more efficient than the existing approaches and are also more applicable in practice.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Novel exact and heuristic algorithms for resequencing cars to minimize setup costs in automotive paint shops are proposed. </LI> <LI> Incorporating strong lower and upper bounds in the dynamic programming framework reduces computation time significantly. </LI> <LI> Proposed algorithms are more efficient than existing approaches and also more practically applicable. </LI> <LI> Shows well-tailored exact algorithms can be more efficient than meta-heuristic algorithms. </LI> </UL> </P>

Healing of Microdefects in SSZ-13 Membranes via Filling with Dye Molecules and Its Effect on Dry and Wet CO₂ Separations

Hong, Sungwon,Kim, Dongjae,Jeong, Yanghwan,Kim, Eunjoo,Jung, Jae Chil,Choi, Nakwon,Nam, Jaewook,Yip, Alex C. K.,Choi, Jungkyu American Chemical Society 2018 Chemistry of materials Vol.30 No.10

<P>It is quite challenging to avoid microdefect formation during hydrothermal growths and/or calcination processes, while manufacturing high-quality zeolite membranes in a reproducible manner. Even less than 1% of defects, which generally provide nonselective pathways, will considerably worsen the intrinsic, high molecular sieving-based separation performance of a continuous zeolite membrane. Herein, we propose a simple and reliable method for blocking defects using water-soluble dye molecules, which were originally used for the visualization of nonzeolitic, defective structures in a zeolite membrane. Because the dye molecules are ∼1 nm in size, they cannot diffuse into the zeolitic pores and selectively access the defects. For the demonstration of dye-based defect healing, we chose a siliceous chabazite type SSZ-13 zeolite membrane (pore size = 0.37 × 0.42 nm<SUP>2</SUP>) with some degree of defects and investigated the effect of defect healing on the final CO<SUB>2</SUB> separation performance. Because the defects were gradually filled by the dye molecules, both CO<SUB>2</SUB>/N<SUB>2</SUB> and CO<SUB>2</SUB>/CH<SUB>4</SUB> separation performances were concomitantly increased. Intriguingly, the CO<SUB>2</SUB> perm-selectivity test with ternary mixtures including H<SUB>2</SUB>O vapor (the third largest component in the flue and natural/shale/bio gas streams) in the feed diminished CO<SUB>2</SUB> separation performance. This could be ascribed to inhibited transport of the fast permeating species, here CO<SUB>2</SUB>, from the adsorbed H<SUB>2</SUB>O molecules on the dye-treated and water-friendly (relatively hydrophilic) membrane surface. On the contrary, the intact, siliceous (water-repelling or hydrophobic) SSZ-13 membranes showed improved CO<SUB>2</SUB> perm-selectivities in the presence of H<SUB>2</SUB>O vapor, seemingly due to defect blocking by the physisorbed H<SUB>2</SUB>O molecules.</P> [FIG OMISSION]</BR>

A family with X-linked Cornelia de Lange syndrome due to a novel SMC1A missense mutation identified by multi-gene panel sequencing

Hong, Sungwon,Lee, Cha Gon Korean Society of Medical Genetics and Genomics 2018 대한의학유전학회지 Vol.15 No.1

Cornelia de Lange syndrome (CdLS) is a rare, clinically and genetically heterogeneous, multi-system developmental disorder caused by mutations in genes that encode components of the cohesin complex. X-linked CdLS caused by an SMC1A mutation is an extremely rare disease characterized by phenotypes milder than those of classic CdLS. In the Republic of Korea, based on a literature review, one family with SMC1A-related CdLS with mild phenotypes has been genetically confirmed to date. In this study, we describe the clinical features of a Korean boy with a hemizygous novel missense mutation and his mother with a heterozygous mutation, i.e., c.2447G>A (p.Arg816His) in SMC1A, identified by multi-gene panel sequencing. The proband had a mild phenotype with typical facial features and his mother exhibited a mild, subclinical phenotype. This study expands the clinical spectrum of patients with X-linked CdLS caused by SMC1A variants. Moreover, these findings reinforce the notion that a dominant negative effect in a carrier female with a heterozygous mutation in SMC1A results in a phenotype milder than that in a male patient with the same mutation.

Quantitative elucidation of the elusive role of defects in polycrystalline MFI zeolite membranes on xylene separation performance

Hong, Sungwon,Kim, Dongjae,Richter, Hannes,Moon, Jong-Ho,Choi, Nakwon,Nam, Jaewook,Choi, Jungkyu Elsevier 2019 Journal of membrane science Vol.569 No.-

<P><B>Abstract</B></P> <P>The defect structure in a <I>c</I>-out-of-plane oriented MFI membrane was quantitatively analyzed by processing images obtained by fluorescence confocal optical microscopy (FCOM). The MFI membranes were placed in contact with a dye solution at a fixed concentration (1 mM) for 2, 4, and 8 d and at different concentrations (0.01, 0.1, and 1 mM) for 8 d. This approach led to the identification and understanding of two types of defects (cracks and grain boundary defects). The representative quantitative properties (porosity and tortuosity) relevant to the defects were obtained via the image processing. Furthermore, the estimation of the defect sizes was complemented by the use of a one-dimensional permeation model for the molar flux of the <I>p</I>-/<I>o</I>-xylene components across the <I>c</I>-oriented MFI membrane. Using this combination, we found that although the amount of defects in the whole zeolite membrane was close to ~ 1%, they provided non-selective, facile pathways that accounted for ~ 58% of the total molar flux of faster permeating <I>p</I>-xylene. Surprisingly, despite the lower density (pixel-based area fraction) of cracks, wider cracks (~ 7.8–8.2 nm) accounted for the much higher molar flux of permeation components compared to major, but narrower grain boundary defects (~ 1–2 nm). Indeed, the cracks mainly deteriorated a <I>p</I>-/<I>o</I>-xylene separation performance of the <I>c</I>-oriented MFI membrane. Finally, we found that the crack size increased in the presence of <I>p</I>-xylene so that the molar flux of <I>o</I>-xylene in the binary mixture was significantly increased, thus reducing the <I>p</I>-/<I>o</I>-xylene separation performance. This behavior was ascribed to the flexible MFI zeolite structure after the adsorption of <I>p</I>-xylene.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Defects in a MFI zeolite membrane were quantitatively analyzed by a FCOM technique. </LI> <LI> Two types of defects (cracks and grain boundary defects) were investigated. </LI> <LI> The defects with coverage of less than 1% significantly reduced membrane performance. </LI> <LI> Fewer but wider cracks had a stronger influence on the final membrane performance. </LI> <LI> Structural transformation of the MFI zeolite due to <I>p</I>-xylene opened defect spaces. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Sonic vibration enhances the neural differentiation of human umbilical cord-derived MSCs

Sungwon HONG,Hyunjung KIM,Chanwha KIM 한국생물공학회 2013 한국생물공학회 학술대회 Vol.2013 No.10

Seasonal Fluctuation in P-type Ca^2+ Current Density in a Crustacean Motoneuron

Hong, Sungwon 동국대학교 경주대학 1999 東國論集 Vol.18 No.-

민물가재 운동신경세포 F3에서의 Ca^2+ 전류량의 계절에 따른 변화를 보기 위하여 두 개의 미세전극을 사용한 voltage-clamp 방법으로 high-voltage activated (HVA) Ca^2+ channel의 전류량을 3 년간 측정하였다. Ca^2+ 전류 밀도의 크기는 겨울에 가장 크고 여름에 가장 작았으며, 겨울에 비하여 약 17% 정도 작았다. 그리고 봄과 가을철에는 중간크기를 나타내었다. 이러한 계절에 따른 Ca^2+ 전류 밀도의 변화가 어떤 Ca^2+ channel의 변화에 기인하는가를 알기 위하여 P-type Ca^2+ channel 억제제인 ω-agatoxin IVA을 사용하여 전체 Ca^2+ 전류를 ω-agatoxin IVA에 억제되는 P-type Ca^2+ 전류와 ω-agatoxin IVA에 억제되지 않는 non-P-type Ca^2+ 전류인 두 개의 성분으로 구분하였다. 이때 Ca^2+의 ω-agatoxin IVA에 대한 억제효과를 줄이기 위해 Ca^2+을 Ba^2+로 치환하였다. 겨울철의 P-type Ba^2+ 전류 밀도는 여름철에 비하여 약 19% 정도 크게 나타났으나, non-P-type Ba^2+ 전류 밀도는 계절에 따른 변화를 보이지 않았다. 그러나 Ba^2+ 전류의 막전압에 따른 활성화 특성에 있어서 각각의 P-type과 non-P-type Ba^2+ 전류는 아무런 차이를 보이지 않았다. 이 실험 결과들은 여름철 Ca^2+ 전류의 감소는 기능적인 P-type Ca^2+ channel들의 수적인 감소로 인하여 P-type Ca^2+ 전류량이 감소됨을 나타낸다. 동일한 F3 운동신경세포의 활동도를 인위적으로 증가시킬 경우 P-type Ca^2+ channel이 선택적으로 불활성화 되는 점으로 미루어 볼 때, 계절에 따른 P-type Ca^2+ 전류량의 선택적인 변화는 동물의 활동도가 여름철에 가장 높기 때문으로 보여진다. Using two-electrode voltage-clamp technique, seasonal changes in the high-voltage activated (HVA) Ca^2+ current was measured in the call body of a crayfish abdominal phasic motoneuron, F3, for a period of 3-years. The magnitude of Ca^2+ current density (nA/nF) was approximately 17% greater in the winter than that in the summer; spring and fall values were intermediate. To further examine this seasonal fluctuation in the Ca^2+ current, the whole macroscopic Ca^2+ current was characterized into two Ca^2+ components as ω-agatoxin IVA-sensitive (P-type) and ω-agatoxin IVA-resistant (non-P-type) Ca^2+ current by using ω-agatoxin IVA, a specific toxin for P-type Ca^2+ channel. The magnitude of P-type Ca^2+ current was 19% greater in the winter than in the summer, whereas there were no significant changes in the non-P-type Ca^2+ current. However, the activation voltages and kinetics of these Ca^2+ currents remained constant throughout the year. These results suggest that the change in the number of functional P-type Ca^2+ channels, not their properties, is responsible for the seasonal changes in the Ca^2+ current. This selective inactivation of P-type Ca^2+ channel is probably due to higher activity levels of the animals developing in the summer since experimentally increased impulse activity in this motoneuron reduces this P-type Ca^2+ current.

DEEP-South: The Progress Report

Hong-Kyu Moon,Myung-Jin Kim,Jintae Park,Youngmin Jeong Ahn,Hongu Yang,Hee-Jae Lee,Dong-Heun Kim,Dong-Goo Roh,Young-Jun Choi,Hong-Suh Yim,Sang-Min Lee,SungWon Kwak,DEEP-South Team 한국천문학회 2018 天文學會報 Vol.43 No.1

Analysis of structural defects in MFI membranes by Fluorescene Confocal Optical Microscopy

Sungwon Hong,Jungkyu Choi,Dongjae Kim,Nakwon Choi,Jaewook Nam 한국막학회 2017 한국막학회 총회 및 학술발표회 Vol.2017 No.05

Defects of zeolite membranes often lower their separation performance. Thus, the investigation of the defects is highly critical in achieving high separation performance. While general characterization methods (e.g. scanning electron microscopy; SEM) that examine the membrane surface cannot detect defects, the FCOM measurement is able to identify the defective structure inside the zeolite membrane using dye molecules of appropriate size [1]. In this work, various dyeing conditions (times and concentrations) were applied to a MFI zeolite membrane in an attempt to investigate the defective structure. Furthermore, the quantitative analysis is practiced to measure the defects in numerical form.