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Effect of Gaze Direction of Human Faces on Cosmetic Paper Advertisement
Seungji Lee,Sung-Phil Kim 한국HCI학회 2017 한국HCI학회 학술대회 Vol.2017 No.2
In cosmetic paper advertisement, models are important components for marketers to imprint the products to customers (e.g. Kim’s essence). One possible method to attract attention from customers is gaze direction of a model. This study aimed to identify how a model’s gaze direction affects a customer’s gaze pattern and how it relates to purchase intention. The gender effect was also investigated. The result showed a near-marginally significant observation that when a model gazed toward us, fixation duration on the model became longer and the number of visit increased. In addition, customers attracted by the model at the first time were likely to buy the product. The different gaze patterns between male and female were observed. The study indicates that the gaze direction of a model can affect fixation duration on model, which is correlated with the first fixation on model and finally leading to purchase behavior.
Kim, Seong Kwang,Shim, Jae-Phil,Geum, Dae-Myeong,Kim, Jaewon,Kim, Chang Zoo,Kim, Han-Sung,Song, Jin Dong,Choi, Sung-Jin,Kim, Dae Hwan,Choi, Won Jun,Kim, Hyung-Jun,Kim, Dong Myong,Kim, Sanghyeon Institute of Electrical and Electronics Engineers 2018 IEEE transactions on electron devices Vol.65 No.5
<P>In this paper, we fabricated In<SUB>0.53</SUB>Ga<SUB>0.47</SUB>As-on insulator (OI) MOSFETs on Si substrates with different doping types to mimic ground plane doping using direct wafer bonding and epitaxial lift-off (ELO) techniques. We investigated the impact of doping types on the ground plane and the backgate biasing, which are important and preferable components in monolithic 3-D (M3D) integration, on the electrical properties of MOSFETs, such as the threshold voltage ( <TEX>${V} _{T}$</TEX>) and the effective mobility ( <TEX>$\mu _{\textsf {eff}}$</TEX>). It was found that <TEX>${V} _{T}$</TEX> and <TEX>$\mu _{\textsf {eff}}$</TEX> were significantly modulated by the backsubstrate doping and the backbiasing. These observations were explained by the change of carrier distributions, which were confirmed by technology computer-aided design simulation. Furthermore, we investigated the reusability of InP donor substrates for sequential epitaxial growth after ELO process toward a cost-effective M3D integration with the In<SUB>0.53</SUB>Ga<SUB>0.47</SUB>As channel.</P>
Combination treatment of Cetuximab and photodynamic therapy in SNU-1041 squamous cancer cell line
Kim, Sun Gon,Hong, Ji Won,Boo, Sung Hyun,Kim, Myung Gu,Lee, Kang Dae,Ahn, Jin Chul,Hwang, Hee Jun,Shin, Jang-In,Lee, Sang Joon,Oh, Jang Keun,Chung, Phil Sang Spandidos Publications 2009 ONCOLOGY REPORTS Vol.22 No.4
<P>Cetuximab (Erbitux) has been highlighted for its anti-proliferative effects in solid tumors and it is currently used as an adjuvant modality with other anti-cancer treatments. Photodynamic therapy (PDT) is used widely in many specialties of medicine. This study evaluated the efficacy of a combination treatment of two modalities (Cetuximab, PDT) both in vivo and in vitro. The SNU-1041 cell line was used for both the in vitro and in vivo studies. The in vivo and in vitro experiments were each classified into four groups, control group, Cetuximab applied group, PDT applied group and combined modality group. A migration study was performed to determine the anti-migration effect of Cetuximab, and a MTT assay was performed to compare the anti-proliferative effect of the modalities in vitro. For the in vivo study, the cells were implanted into 5-week-old nude mice. The measured volume of the tumor for each group was compared as a function of time. In the migration study, the control group showed a longer migration length than the Cetuximab applied group. In the MTT assay, the combination modality group showed less survival than the uni-modality groups. The measured tumor size after treatment showed that the combination treatment was more effective than the single modalities. PDT and Cetuximab are treatment modalities that target different molecular pathways. A combination of these two treatment modalities was found to more effective than an individual treatment. However, further studies will be needed to determine the optimal dose of the photosensitizer and Cetuximab.</P>
Acupuncture Treatment of Adhesive Capsulitis of the Shoulder: A Randomized Controlled Pilot Trial
Kim, Jung-Eun,Kim, Sung-Phil,Kim, Ae-Ran,Park, Hyo-Ju,Kwon, Ojin,Jung, So-Young,Cho, Jung-Hyo,Kim, Joo-Hee,Choi, Sun-Mi Korean AcupunctureMoxibustion Medicine Society 2018 Korean Journal of Acupuncture Vol.35 No.3
Background: Adhesive capsulitis (AC) is a common condition that includes shoulder pain and limited movement. Despite more than 100 years of AC treatment, the most efficacious treatment remains unclear. The aim of this study was to evaluate the feasibility of a randomized controlled trial (RCT) using acupuncture for AC. Methods: Thirty participants with AC were randomly assigned to acupuncture (A) or sham acupuncture (SA) groups. The participants received 15 acupuncture sessions over 6 weeks, and follow-up occurred for an additional 4 weeks thereafter. The primary clinical outcome was the numeric rating scale (NRS) for shoulder pain 6 weeks from the baseline. Secondary outcomes included range of motion (ROM) in the shoulder, the shoulder pain and disability index (SPADI), the EuroQol-5 dimensions (EQ-5D), the Pittsburgh sleep quality index (PSQI), and the patient global impression of change (PGIC). Results: Thirty participants were enrolled out of 37 screened individuals. Recruitment was conducted between August 2014 until May 2015. A total of 28 participants (93%) completed the 6-week intervention, and 26 participants (87%) completed the study. NRS, ROM, SPADI, EQ-5D, PSQI, and PGIC scores improved in both the experimental group and the sham group after 6 weeks, but the difference between the groups was not statistically significant. Adverse events were reported by 12 participants, although these events were not associated with acupuncture. Conclusion: A future RCT for AC may be feasible with some modifications to the recruitment plan and the secondary outcome measurement methods.
Neural Categorization of Vibrotactile Frequency in Flutter and Vibration Stimulations: An fMRI Study
Kim, Junsuk,Chung, Yoon Gi,Chung, Soon-Cheol,Bulthoff, Heinrich H.,Kim, Sung-Phil IEEE 2016 IEEE transactions on haptics Vol.9 No.4
<P>As the use of wearable haptic devices with vibrating alert features is commonplace, an understanding of the perceptual categorization of vibrotactile frequencies has become important. This understanding can be substantially enhanced by unveiling how neural activity represents vibrotactile frequency information. Using functional magnetic resonance imaging (fMRI), this study investigated categorical clustering patterns of the frequency-dependent neural activity evoked by vibrotactile stimuli with gradually changing frequencies from 20 to 200 Hz. First, a searchlight multi-voxel pattern analysis (MVPA) was used to find brain regions exhibiting neural activities associated with frequency information. We found that the contralateral postcentral gyrus (S1) and the supramarginal gyrus (SMG) carried frequency-dependent information. Next, we applied multidimensional scaling (MDS) to find low-dimensional neural representations of different frequencies obtained from the multi-voxel activity patterns within these regions. The clustering analysis on the MDS results showed that neural activity patterns of 20-100 Hz and 120-200 Hz were divided into two distinct groups. Interestingly, this neural grouping conformed to the perceptual frequency categories found in the previous behavioral studies. Our findings therefore suggest that neural activity patterns in the somatosensory cortical regions may provide a neural basis for the perceptual categorization of vibrotactile frequency.</P>
Kim, Sung-Phil,Kang, Mi-Young,Nam, Seok-Hyun The Korean Society for Applied Biological Chemistr 2010 Applied Biological Chemistry (Appl Biol Chem) Vol.53 No.5
Herba Agastache (HA), the dried ground part of Agastache rugosa O. Kuntze, has been shown to have antimicrobial and antitumor properties and can be used to treat infectious diseases including cold and flu. To elucidate the mechanism by which HA elicits pharmaceutical potencies, the effects of HA on nitric oxide (NO) and pro-inflammatory cytokine production in mouse peritoneal macrophages were determined. When HA extract was used in combination with recombinant interferon-${\gamma}$ (rIFN-${\gamma}$), a considerable increase in the NO production was observed, whereas HA alone generally had marginal effect on the NO level. The increased production of NO by rIFN-${\gamma}$ plus HA was dose-dependently inhibited by $N^G$-monomethyl-L-arginine (L-NMMA) and L-$N^6$-(1-iminoethyl)-lysine (L-NIL), L-arginine analogues or pyrrolidine dithiocarbamate (PDTC), a nuclear factor-${\kappa}B$ (NF-${\kappa}B$) inhibitor. Treatment of rIFN-${\gamma}$ plus HA in peritoneal macrophages resulted in an increased production of pro-inflammatory cytokines, such as tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$), interleukin-$1{\beta}$ (IL-$1{\beta}$), and interleukin-6 (IL-6). However, the concentrations of these cytokines substantially decreased with the addition of PDTC. These findings illustrate that the antimicrobial and tumoricidal properties of HA, in combination with rIFN-${\gamma}$, could be attributed to its ability in inducing macrophage activation, such as enhanced production of NO and pro-inflammatory cytokines via the NF-${\kappa}B$ signaling pathway.
Decoding pressure stimulation locations on the fingers from human neural activation patterns
Kim, Junsuk,Chung, Yoon Gi,Chung, Soon-Cheol,Bü,lthoff, Heinrich H.,Kim, Sung-Phil Wolters Kluwer Health | Lippincott Williams Wilkin 2016 NEUROREPORT - Vol.27 No.16
<P>In this functional MRI study, we investigated how the human brain activity represents tactile location information evoked by pressure stimulation on fingers. Using the searchlight multivoxel pattern analysis, we looked for local activity patterns that could be decoded into one of four stimulated finger locations. The supramarginal gyrus (SMG) and the thalamus were found to contain distinct multivoxel patterns corresponding to individual stimulated locations. In contrast, the univariate general linear model analysis contrasting stimulation against resting phases for each finger identified activations mainly in the primary somatosensory cortex (S1), but not in SMG or in thalamus. Our results indicate that S1 might be involved in the detection of the presence of pressure stimuli, whereas the SMG and the thalamus might play a role in identifying which finger is stimulated. This finding may provide additional evidence for hierarchical information processing in the human somatosensory areas.</P>
Occult Intertrochanteric Fracture Mimicking the Fracture of Greater Trochanter
( Phil Hyun Chung ),( Suk Kang ),( Jong Pil Kim ),( Young Sung Kim ),( Ho Min Lee ),( In Hwa Back ),( Kyeong Soo Eom ) 대한고관절학회 2016 Hip and Pelvis Vol.28 No.2
Purpose: Occult intertrochanteric fractures are misdiagnosed as isolated greater trochanteric fractures in some cases. We investigated the utility of three-dimensional computed tomography (3D-CT) and magnetic resonance imaging (MRI) in the diagnosis and outcome management of occult intertrochanteric fractures. Materials and Methods: This study involved 23 cases of greater trochanteric fractures as diagnosed using plain radiographs from January 2004 to July 2013. Until January 2008, 9 cases were examined with 3D-CT only, while 14 cases were screened with both 3D-CT and MRI scans. We analyzed diagnostic accuracy and treatment results following 3D-CT and MRI scanning. Results: Nine cases that underwent 3D-CT only were diagnosed with isolated greater trochanteric fractures without occult intertrochanteric fractures. Of these, a patient with displacement received surgical treatment. Of the 14 patients screened using both CT and MRI, 13 were diagnosed with occult intertrochanteric fractures. Of these, 11 were treated with surgical intervention and 2 with conservative management. Conclusion: Three-dimensional CT has very low diagnostic accuracy in diagnosing occult intertrochanteric fractures. For this reason, MRI is recommended to confirm a suspected occult intertrochanteric fracture and to determine the most appropriate mode of treatment.