Improvement and Application for Environmental Conservation Value Assessment Map (ECVAM) of Nationwide Land in Korea

Moung Jin Lee,Seong Woo Jeon,Min Jeong Jo,Won Kyong Song,Byung Jin Kang 大韓遠隔探査學會 2007 大韓遠隔探査學會誌 Vol.23 No.5

This study is aiming at improving the Environmental Conservation Value Assessment Map (ECVAM) of National Land in Korea. The ECVAM items are composed of legal and environmental/ecological assessments. A popular method applied to ECVAM is an overlay environmental/ecological assessment items. The purpose of this study is to offer complementary items of the ECVAM by examining assessment items. In this study we assessed the ECVAM by five methods. Method 1 is Grade 1 areas of each administrative district; Method 2 is comparing overlapped areas of each assessment items Grade 1, 2 and permission of each assessment items duplication; Method 3 is Grade 1, 2 areas by only singular assessment items; Method 4 is Grade 1 areas only of Method 2; and Method 5 is Grade 2 areas only of Method 2. Method 1 showed Seoul and other metropolitan cities revealed a large proportion of Grade I regions by the legal assessment items. Gang won-Do, showed a large proportion of Grade I regions by the environmental/ecological assessment item. Method 2 showed 93.4 % of diameter Grade II (standard for stability); forest diameter item accounted for 99.9 % by Method 3, Method 4 showed 95.7 % of forest diameter, and forest density accounted for 66.4 % by Method 5. This study contributes to reduce the complexity in the process of manufacturing ECVAM of National Land, and to raise the flexibility in the process of managing and updating this map.

Improvement and Application for Environmental Conservation Value Assessment Map(ECVAM) of Nationwide Land in Korea

Lee, Moung-Jin,Jeon, Seong-Woo,Jo, Min-Jeong,Song, Won-Kyong,Kang, Byung-Jin The Korean Society of Remote Sensing 2007 大韓遠隔探査學會誌 Vol.23 No.5

This study is aiming at improving the Environmental Conservation Value Assessment Map(ECVAM) of National Land in Korea. The ECVAM items are composed of legal and environmental/ecological assessments. A popular method applied to ECVAM is an overlay environmental/ecological assessment items. The purpose of this study is to offer complementary items of the ECVAM by examining assessment items. In this study we assessed the ECVAM by five methods. Method 1 is Grade 1 areas of each administrative district; Method 2 is comparing overlapped areas of each assessment items Grade 1, 2 and permission of each assessment items duplication; Method 3 is Grade 1, 2 areas by only singular assessment items; Method 4 is Grade 1 areas only of Method 2; and Method 5 is Grade 2 areas only of Method 2. Method 1 showed Seoul and other metropolitan cities revealed a large proportion of Grade I regions by the legal assessment items. Gang won-Do, showed a large proportion of Grade I regions by the environmental/ecological assessment item. Method 2 showed 93.4% of diameter Grade II(standard for stability); forest diameter item accounted for 99.9% by Method 3, Method 4 showed 95.7% of forest diameter, and forest density accounted for 66.4% by Method 5. This study contributes to reduce the complexity in the process of manufacturing ECVAM of National Land, and to raise the flexibility in the process of managing and updating this map.

데드리프트와 업라이트로우 시 운동강도에 따른 근활성도 평가

( Won Jun Cho ),( Ju Won Song ),( Myung Soo Choi ),( Nam Yim Kim ),( Ryong Kim ),( Chang Min Lee ),( Jae Heon Hong ),( Gun Woo Kang ),( Young Jin Moon ) 한국운동역학회 2021 한국운동역학회지 Vol.31 No.4

Objective: The purpose of this study was to evaluate 16 muscles activity according to three exercise intensity when performing Deadlift and Upright row. Method: To accomplish the purpose of the study, subjects (n=10) were performed Electromyography (EMG) measurement for 16 different muscles. The experimental movements were Deadlift and Upright row, measured five times for each intensity (40%, 60%, 80%) of 1RM. This study normalized the EMG values through RVC for comparative analysis. Results: The results were summarized as follows: As a result of Deadlift, there was significant difference in the mean EMG value according to the exercise intensity in all muscles except RA, PM and BB (p<.05). As a result of Upright row, There was significant difference in the mean EMG value according to the exercise intensity in all muscles except BF, TA, GN, RA and UT (p<.05). Conclusion: This study allowed us to know the activities of major muscles according to the exercise intensity for 16 different muscles when performing Deadlift and Upright row.

Diagnostic and prognostic impact of fluorodeoxyglucose-positron emission tomography in diagnosing intraductal papillary neoplasms of the bile duct of the liver

Jin Uk Choi,Shin Hwang,Chul-Soo Ahn,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Jae Seung Kim,Seung-Mo Hong 대한외과학회 2022 Annals of Surgical Treatment and Research(ASRT) Vol.102 No.6

Purpose: Malignant intraductal papillary neoplasm of the bile duct of the liver (IPNB-L) cannot readily be diagnosed through preoperative CT or MRI, but fluorodeoxyglucose (FDG)-PET is a viable alternative. This study evaluated the diagnostic and prognostic impacts of FDG-PET in patients with IPNB-L. Methods: This was a retrospective single-center study of 101 IPNB-L patients who underwent hepatectomy between 2010 and 2019. Results: Mean age was 64.4 ± 8.3 years and 76 (75.2%) were male. Anatomical hepatic resection was performed in 99 (98.0%). Concurrent bile duct resection and pancreaticoduodenectomy were performed in 41 (40.6%) and 1 (1.0%), respectively. R0 and R1 resections were performed in 88 (87.1%) and 13 (12.9%), respectively. Low-grade intraepithelial neoplasia and high-grade neoplasia/invasive carcinoma were diagnosed in 19 (18.8%) and 82 (81.2%), respectively. Median FDG-PET maximal standardized uptake values (SUVmax) in low-grade neoplasia and high-grade neoplasia/carcinoma were 3.6 (range, 1.7–7.6) and 5.2 (range, 1.5–18.7) (P = 0.019), respectively. Receiver operating characteristic curve analysis of SUVmax showed area under the curve of 0.674, with sensitivity of 84.2% and specificity of 47.4% at SUVmax cutoff of 3.0. This cutoff had no significant influence on tumor recurrence (P = 0.832) or patient survival (P = 0.996) in patients with IPNB-L of high-grade neoplasia or invasive carcinoma. Conclusion: IPNB-L is a rare type of biliary neoplasm and encompasses a histological spectrum ranging from benign disease to invasive carcinoma. An FDG-PET SUVmax cutoff of 3.0 appears to effectively discern high-grade neoplasia/carcinoma from low-grade neoplasia, which will assist with the surgical strategy for these cases.

Study on Crossing Tendencies of Birds by Road Type for Validation of Wildlife Crossing Structures Targeting Avian Species

Song, Eui-Geun,Lee, Hwa-Su,Park, Hee-Bok,Woo, Dong-Gul,Park, Tae-Jin,Chun, Su-Won,Sim, Seung-Woo,Cha, Hyoun-Gi,Lim, Anya,Choi, Tae-Young Institute of Forest Science 2018 Journal of Forest Science Vol.34 No.2

The purpose of this study is to compare the bird crossing of roads by type (Expressway 1, railroad-provincial road and Highway 4) and the crossing of roads according to the size of birds. The greatest number of avian species and individuals crossing road per 10 minutes were found on railroad-provincial road ($8.96{\pm}1.92$ and $29.33{\pm}11.94$, respectively), while the lowest number of avian species and individuals were found on Expressway 1 ($2.96{\pm}1.04$ and $6.13{\pm}2.89$, respectively), which has the widest width. In addition, the number of small-sized bird (<20 cm) crossing the Expressway 1, railroad-provincial road, and Highway 4 was lower than that of the medium-sized bird (${\geq}20cm$). Current wildlife crossing structures have been focused on mammals, amphibians and reptiles, but future structures should also consider birds.

Time trends of thyroglobulin antibody in ablated papillary thyroid carcinoma patients: Can we predict the rate of negative conversion?

Song, Eyun,Ahn, Jonghwa,Oh, Hye-Seon,Jeon, Min Ji,Kim, Won Gu,Kim, Won Bae,Shong, Young Kee,Baek, Jung Hwan,Lee, Jeong Hyun,Ryu, Jin Sook,Chung, Ki Wook,Hong, Suck Joon,Kim, Tae Yong Elsevier 2019 Oral oncology Vol.91 No.-

<P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>Persistence of thyroglobulin antibody (TgAb) in patients with papillary thyroid carcinoma (PTC) years after total thyroidectomy (TT) followed by ablation occurs even without any evidence of structural disease. Few studies have studied the natural course of TgAb positivity and factors that may influence this course. The present study evaluated the time trends of TgAb in ablated PTC patients and aimed to identify the predictive factors for the rate of negative conversion of TgAb.</P> <P><B>Materials and methods</B></P> <P>Overall, 1279 patients who underwent TT and subsequent ablation for PTC, with available data on thyroid peroxidase Ab (TPOAb) and TgAb prior to surgery (preop-) and ablation (abl-) were enrolled. Patients with initial distant metastasis or recurrence during follow-up were excluded.</P> <P><B>Results and conclusion</B></P> <P>Preop-TgAb was positive in 24.9% of patients (n = 319), whereas abl-TgAb positivity decreased to 12.8% (n = 164). In 164 patients positive for abl-TgAb, TgAb in patients with higher abl-TgAb levels decreased more gradually than those observed in patients with lower abl-TgAb levels (p < 0.001). Furthermore, in patients within the same range of abl-TgAb levels, patients positive for abl-TPOAb had a higher rate of negative conversion of TgAb compared with negative patients for abl-TPOAb (log rank p < 0.001). TPOAb significantly increased the rate of negative conversion in multivariate analysis adjusted for abl-TgAb (odds ratio 1.59, 95% confidence interval 1.11–2.28, p = 0.011). This study clearly showed that abl-TgAb titers and abl-TPOAb status can predict the rate of negative conversion. These findings can guide the optimal timing for additional examination in patients positive for TgAb during follow-up.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Positivity for preoperative TgAb in patients with PTC is higher than general population. </LI> <LI> The higher the TgAb levels at the time of postoperative ablation, the longer it takes to negative conversion. </LI> <LI> TPOAb status at the time of ablation is also associated with the time required for the disappearance of TgAb. </LI> <LI> TgAb and TPOAb together can predict the rate of negative conversion of TgAb. </LI> </UL> </P>

PKC-β modulates Ca2+ mobilization through Stim1 phosphorylation

Song Hye-Jin,전인숙,김승렬,Park Kwan Sik,Soh Jae-Won,Lee Kwang Youl,Shin Jae-Cheon,Lee Hak-Kyo,Choi Joong-Kook 한국유전학회 2022 Genes & Genomics Vol.44 No.5

Background: Calcium ions play a pivotal role in cell proliferation, differentiation, and migration. Under basal conditions, the calcium level is tightly regulated; however, cellular activation by growth factors increase the ion level through calcium pumps in the plasma membrane and endoplasmic reticulum for calcium signaling. Orai1 is a major calcium channel in the cell membrane of non-excitable cells, and its activity depends on the stromal interaction molecule 1 (Stim1). Several groups reported that the store-operated calcium entry (SOCE) can be modulated through phosphorylation of Stim1 by protein kinases such as extracellular signal-regulated kinase (ERK), protein kinase A (PKA), and p21-activated kinase (PAK). PKC is a protein kinase that is activated by calcium and diacylglycerol (DAG), but it remains unclear what role activated PKC plays in controlling the intracellular calcium pool. Objectives: Here, we investigated whether PKC-β controls intracellular calcium dynamics through Stim1. Methods: Several biochemical methods such as immune-precipitation, site directed mutagenesis, in vitro kinase assay were employed to investigate PKC interaction with and phosphorylation of Stim1. Intracellular calcium mobilization, via Stim1 mediated SOCE channel, were studied using in the presence of PKC activator or inhibitor under a confocal microscope. Results: Our data demonstrate that PKC interacts with and phosphorylates Stim1 in vitro. phosphorylation of Stim1 at its C-terminal end appears to be important in the regulation of SOCE activity in HEK293 and HeLa cells. Additionally, transient intracellular calcium mobilization assays demonstrate that the SOCE activity was inhibited by PKC activators or activated by PKC inhibitors. Conclusion: In sum, our data suggest a repressive role of PKC in regulating calcium entry through SOCE.

POSTER SESSION : STRUCTURE - ACTIVITY RELATIONSHIPS OF AN NK - 2 ANTAGONISTS

( Song Yub Shin ),( Shin Won Kang ),( Jong Myung Ha ),( Bae Jin Ha ) 한국생화학분자생물학회 (구 한국생화학회) 1996 추계학술대회집 Vol.- No.-

Sequence-independent, single-primer amplification next-generation sequencing of Hantaan virus cell culture—based isolates

Song, Dong Hyun,Kim, Won-Keun,Gu, Se Hun,Lee, Daesang,Kim, Jeong-Ah,No, Jin Sun,Lee, Seung-Ho,Wiley, Michael R.,Palacios, Gustavo,Song, Jin-Won Allen Press, etc 2017 The American journal of tropical medicine and hygi Vol.96 No.2

<P>Hantaan virus (HTNV), identified in the striped field mouse (Apodemus agrarius), belongs to the genus Hantavirus of the family Bunyaviridae and contains tripartite RNA genomes, small (S), medium (M), and large (L) segments. HTNV is a major causative for hemorrhagic fever with renal syndrome (HFRS) with fatality rates ranging from 1% to 15% in the Republic of Korea (ROK) and China. Defining of HTNV whole-genome sequences and isolation of the infectious particle play a critical role in the characterization and preventive and therapeutic strategies of hantavirus outbreaks. Next-generation sequencing (NGS) provides an advanced tool for massive genomic sequencing of viruses. However, the isolation of viral infectious particles is a huge obstacle to investigate and develop anti-virals for hantaviruses. Here, we report 12 HTNV isolates from lung tissues of the striped field mouse in the highly HFRS-endemic areas. Sequence-independent, single-primer amplification (SISPA) NGS was attempted to recover the genomic sequences of HTNV isolates. The nucleotide sequence of HTNV S, M, and L segments were covered up to 99.4-100%, 97.5-100%, and 95.6-99.8%, respectively, based on the full length of the prototype HTNV 76-118. The whole-genome sequencing of HTNV isolates was accomplished by additional reverse transcription polymerase chain reaction (RT-PCR) and rapid amplification cDNA ends (RACE) PCR. In conclusion, this study will lead to the attempt and usage of SISPA NGS technologies to delineate the whole-genome sequence of hantaviruses, providing a new era of viral genomics for the surveillance, trace, and disease risk management of HFRS incidents.</P>

Asymptomatic Solitary Renal Metastasis Detected during Surveillance after Curative Surgery for Squamous Cell Carcinoma of Lung

Song, Sung-Heon,Jun, Young-Jin,Paik, Seung-Sam,Kwak, Hyun-Jung,Kim, Sang-Heon,Kim, Tae-Hyung,Sohn, Jang-Won,Shin, Dong-Ho,Park, Sung-Soo,Yoon, Ho-Joo The Korean Academy of Tuberculosis and Respiratory 2011 Tuberculosis and Respiratory Diseases Vol.71 No.6

Non small cell lung cancer (NSCLC) frequently metastasizes to brain, bone, liver, and adrenal glands. While an autopsy of NSCLC reveals some cases of metastasis to the kidney, clinical detection of renal metastases is extremely rare. Furthermore, metastases to the kidney usually present as multifocal or bilateral lesions and solitary renal metastases are usually suspected to be renal cell carcinoma. We now report a case of asymptomatic solitary renal metastasis from a primary squamous cell carcinoma, which was detected by routine surveillance with abdominal CT after curative surgery.