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Palepu Joshna,Patel Shweta,Sinha Sourabh,Mallidi Ranjith Kumar,Naga Karthik Gannina Venkata,Majumdar Budhaditya,Mukhopadhyay S.C.,Kanungo Sayan 한국물리학회 2023 Current Applied Physics Vol.47 No.-
This work investigates a Dielectrically Modulated Electron-Hole Bilayer Tunnel Field Effect Transistor (DM-EHBTFET) architecture for biosensing applications using extensive numerical device simulation. The proposed DM-EHBTFET structure incorporates extended source and drain pockets in the channel to ensure vertical band-to-band tunneling (BTBT) dominated transduction. The underlying device physics and sensing performance of the proposed DM-EHBTFET has been comprehensively analyzed based on the tunneling length sensitivity and drain current sensitivity, respectively. Finally, an extensive comparative performance study has been undertaken against conventional lateral tunneling (LT) and vertical tunneling (VT) based DMTFETs, as well as reported state-of-art DMTFETs and DMFETs. The results demonstrate that the optimized DM-EHBTFET outperforms both conventional LT-/VT- DMTFETs with more than 500 times and 150 times improvements in sensitivity, respectively, over a range of biomolecule specifications, and more than 100 times sensitivity improvement has been observed in DM-EHBTFET over reported DMFETs/DMTFETs for lower biomolecule dielectric constant.
Kinetic model for sorption of divalent heavy metal ions on low cost minerals
Murari Prasad,Aseem Chawla,Rishta Goswami,Shweta Ranshore,Ankita Kulshreshtha,Akhouri Sudhir Kumar Sinha 한국화학공학회 2016 Korean Journal of Chemical Engineering Vol.33 No.2
A mathematical model is proposed that could predict the kinetic parameters for adsorption of divalent heavy metal ions (lead, copper and zinc) onto low-cost adsorbents such as pyrophyllite and rock phosphate using experimental data. The experiments were conducted with the initial concentrations of metal ions ranging from 10mg/L to 100mg/L. The mathematical model is based on the application of the Redlich-Peterson isotherm to mass transfer across the film surrounding the adsorbent. The developed non-linear sorption kinetic (NSK) mathematical model was solved using numerical integration by the trapezoidal method in Microsoft Excel along with the SOLVER function to obtain the best simulated values of the Redlich-Peterson constants A, B, r, the order of reaction n, and the film transfer coefficient α. Dissolution followed by precipitation was found to be the most probable mechanism responsible for heavy metal ion uptake by rock phosphate, while for pyrophyllite physical adsorption was governing mechanism at low concentrations (<100mg/L). The values of parameters A, B, r and α lie in the ranges of 0.015-23.2, 0.00003-3.09, 0.072- 1, and 0.000057-52.8 [(L/mg)(n−1)/min], respectively, under different experimental conditions.
Antenatal Diagnosis of Iniencephaly: Sonographic and MR Correlation: A Case Report
Sona A. Pungavkar,Nisha I. Sainani,Alka S. Karnik,Prita H. Mohanty,Malini A. Lawande,Deepak P. Patkar,Shweta Sinha 대한영상의학회 2007 Korean Journal of Radiology Vol.8 No.4
Iniencephaly is an uncommon and fatal neural tube defect involving the occiput and inion, this occurs together with rachischisis of the cervical and thoracic spine, and retroflexion of the head. We report the ultrasound (US) and magnetic resonance (MR) imaging findings of a case of iniencephaly with clubfeet and arthrogryposis. The diagnosis of iniencephaly is easy to make on ultrasound due to the typical star-gazing fetus. However, the details of the fetal brain and spinal cord may not be adequately delineated on US. We found MR imaging to be superior for depicting central nervous system abnormalities. MR imaging has evolved as an imaging modality and it is complementary to fetal US, yet US remains the screening modality of choice.