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RISS 인기검색어
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- 저자 : Sarah Khan (검색결과 13 건)
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Khan, Hafiz,Saxena, Anshul,Perisetti, Abhilash,Rafiq, Aamrin,Gabbidon, Kemesha,Mende, Sarah,Lyuksyutova, Maria,Quesada, Kandi,Blakely, Summre,Torres, Tiffany,Afesse, Mahlet Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.12
Background: Breast cancer is a worldwide public health concern and is the most prevalent type of cancer in women in the United States. This study concerned the best fit of statistical probability models on the basis of survival times for nine state cancer registries: California, Connecticut, Georgia, Hawaii, Iowa, Michigan, New Mexico, Utah, and Washington. Materials and Methods: A probability random sampling method was applied to select and extract records of 2,000 breast cancer patients from the Surveillance Epidemiology and End Results (SEER) database for each of the nine state cancer registries used in this study. EasyFit software was utilized to identify the best probability models by using goodness of fit tests, and to estimate parameters for various statistical probability distributions that fit survival data. Results: Statistical analysis for the summary of statistics is reported for each of the states for the years 1973 to 2012. Kolmogorov-Smirnov, Anderson-Darling, and Chi-squared goodness of fit test values were used for survival data, the highest values of goodness of fit statistics being considered indicative of the best fit survival model for each state. Conclusions: It was found that California, Connecticut, Georgia, Iowa, New Mexico, and Washington followed the Burr probability distribution, while the Dagum probability distribution gave the best fit for Michigan and Utah, and Hawaii followed the Gamma probability distribution. These findings highlight differences between states through selected sociodemographic variables and also demonstrate probability modeling differences in breast cancer survival times. The results of this study can be used to guide healthcare providers and researchers for further investigations into social and environmental factors in order to reduce the occurrence of and mortality due to breast cancer.
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Evaluation of rice root oxidizing potential using digital image analysis
Sarah Louise Atulba,Jessie Gutierrez,김길원,김상윤,Muhammad Israr Khan,이용복,김필주 한국응용생명화학회 2015 Applied Biological Chemistry (Appl Biol Chem) Vol.58 No.3
The aerenchymal transport of oxygen to rice roots has significantly influenced the anaerobic root zone of flooded paddy soils. Therefore, the visualization of redox dynamics may be useful to characterize rice root oxidation potentials and the dynamics of redox-influenced ions in the root zone of paddy soils. In order to investigate the interaction between root oxidation potential and Fe uptake of (a) six different rice cultivars (Oryza sativa L.; Chuchung, Dongjin, Ilmi, Junam, Nampyeong, and Samkwang) were monitored in a flooded paddy soil with the aid of rhizotron experiment throughout the vegetation period, (b) digital images of the root zone were taken at the important growing stages, and (c) rice Fe uptake was characterized simultaneously. The images were processed by image analysis to display the reduction and oxidation areas in the root zones, and the distinct areas which were colorized due to varying soil redox changes were localized and quantified. Oxidized areas were mainly observed in the surrounding active roots and in a distinct layer on the soil surface. The selected rice cultivars have shown significantly different root-oxidized areas at the same rice growing stage. Root-oxidized area was significantly and positively correlated with total Fe content of rice root, but negatively correlated with the inner root Fe content. Rice cultivars having higher root oxidation potential precipitated more Fe on the outer root surface in the form of Fe plaques. In conclusion, digital image analysis is an effective tool for evaluating the oxidizing potential of rice root under anaerobic soil condition.
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Razaq Sarah,Geffner James,Khan Asma,Mee Harry,Udensi Cynthia,Anwar Fahim 대한외상학회 2023 大韓外傷學會誌 Vol.36 No.3
A Morel-Lavallée lesion results from a degloving injury between the muscle fascia and the subcutaneous layer. It is most commonly found in the trochanteric area but can occur at other sites. The treatment of the condition varies according to the medical circumstances, as well as the size and chronicity of the condition. A case of large (18×6 and 10×5 cm) bilateral posttraumatic Morel-Lavallée lesions with no underlying bone fracture is presented; the case occurred in a 49-year-old male patient 4 weeks posttrauma. Ultrasound scans showed bilateral large collections of anechoic fluid, which were aspirated under ultrasound guidance and further managed by compression bandages. There were no further complications. The objective of this case report is to present this unique and educational case, as well as to provide an overview of the pathophysiology, diagnosis, and management of Morel-Lavallée lesions. We conclude by discussing the importance of having a high index of suspicion to ensure early detection and prompt treatment of such lesions to avoid complications.
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Evaluation of rice root oxidizing potential using digital image analysis
Atulba, Sarah Louise,Gutierrez, Jessie,Kim, Gil Won,Kim, Sang Yoon,Khan, Muhammad Israr,Lee, Yong Bok,Kim, Pil Joo The Korean Society for Applied Biological Chemistr 2015 Applied Biological Chemistry (Appl Biol Chem) Vol.58 No.3
The aerenchymal transport of oxygen to rice roots has significantly influenced the anaerobic root zone of flooded paddy soils. Therefore, the visualization of redox dynamics may be useful to characterize rice root oxidation potentials and the dynamics of redox-influenced ions in the root zone of paddy soils. In order to investigate the interaction between root oxidation potential and Fe uptake of (a) six different rice cultivars (Oryza sativa L.; Chuchung, Dongjin, Ilmi, Junam, Nampyeong, and Samkwang) were monitored in a flooded paddy soil with the aid of rhizotron experiment throughout the vegetation period, (b) digital images of the root zone were taken at the important growing stages, and (c) rice Fe uptake was characterized simultaneously. The images were processed by image analysis to display the reduction and oxidation areas in the root zones, and the distinct areas which were colorized due to varying soil redox changes were localized and quantified. Oxidized areas were mainly observed in the surrounding active roots and in a distinct layer on the soil surface. The selected rice cultivars have shown significantly different root-oxidized areas at the same rice growing stage. Root-oxidized area was significantly and positively correlated with total Fe content of rice root, but negatively correlated with the inner root Fe content. Rice cultivars having higher root oxidation potential precipitated more Fe on the outer root surface in the form of Fe plaques. In conclusion, digital image analysis is an effective tool for evaluating the oxidizing potential of rice root under anaerobic soil condition.
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Stefan Lam,Sarah Khan,Robert Hutchins,Tim Fotheringham 소화기인터벤션의학회 2022 International journal of gastrointestinal interven Vol.11 No.2
A 56-year-old male underwent a Whipple procedure for duodenal stricture secondary to a 32-mm duodenal adenocarcinoma. The patient presented again 66 months later with obstructive jaundice caused by an obstruction in the afferent loop. Biliary drainage was performed to relieve the obstruction. Two attempts to cross the occlusion were performed, but these were both unsuccessful. Percutaneous transhepatic stent deployment through the obstruction has previously been described in similar cases but was not feasible in this case. An attempt at retrograde cannulation was performed from a direct puncture of the bowel but this failed. Rather than abandoning the case, an extra-anatomic approach was taken by passing a needle across the point of malignant obstruction forming a new track between the Roux loop and small bowel, enabling a covered stent to be placed and relieving the biliary obstruction. This avoided the need for permanent external biliary drainage and its associated complications. Extra-anatomic percutaneous stenting is a viable alternative for the treatment of malignant afferent loop obstruction following pancreaticoduodenectomy.
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Stefan Lam,Sarah Khan,Robert Hutchins,Tim Fotheringham 소화기인터벤션의학회 2022 Gastrointestinal Intervention Vol.11 No.2
A 56-year-old male underwent a Whipple procedure for duodenal stricture secondary to a 32-mm duodenal adenocarcinoma. The patient presented again 66 months later with obstructive jaundice caused by an obstruction in the afferent loop. Biliary drainage was performed to relieve the obstruction. Two attempts to cross the occlusion were performed, but these were both unsuccessful. Percutaneous transhepatic stent deployment through the obstruction has previously been described in similar cases but was not feasible in this case. An attempt at retrograde cannulation was performed from a direct puncture of the bowel but this failed. Rather than abandoning the case, an extra-anatomic approach was taken by passing a needle across the point of malignant obstruction forming a new track between the Roux loop and small bowel, enabling a covered stent to be placed and relieving the biliary obstruction. This avoided the need for permanent external biliary drainage and its associated complications. Extra-anatomic percutaneous stenting is a viable alternative for the treatment of malignant afferent loop obstruction following pancreaticoduodenectomy.
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Role of Peroral Endoscopic Myotomy (POEM) in the Management of Esophageal Diverticula
Bogdan P. Miutescu,Sarah Khan,Shruti Mony,Mouen A Khashab 대한소화기내시경학회 2020 Clinical Endoscopy Vol.53 No.6
Esophageal diverticula are uncommon; however, when present, they can cause symptoms of dysphagia, regurgitation, and chest pain. Based on location and pathophysiological characteristics, they are classified as pulsion- and traction-type diverticula. In the past, theopen surgical approach was the only treatment available; however, in the past few decades, transoral incisionless approaches in theform of rigid and flexible endoscopy have gained popularity. Diverticular peroral endoscopic myotomy has emerged as an alternativetreatment option. In this paper, we reviewed the role of peroral endoscopic myotomy as a treatment option for different types ofesophageal diverticula. Although a safe and effective procedure, this novel submucosal tunneling technique for the treatment ofesophageal diverticula requires further validation, and head-to-head comparisons between the different approaches for the treatmentof esophageal diverticula are warranted.
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Recent advances in transarterial embolotherapies in the treatment of hepatocellular carcinoma
( Edward Wolfgang Lee ),( Sarah Khan ) 대한간학회 2017 Clinical and Molecular Hepatology(대한간학회지) Vol.23 No.4
Management of hepatocellular carcinoma (HCC) can be maximized with the utilization of multiple treatment modalities including transplant, surgical resection and locoregional therapies including ablative therapies and transarterial embolotherapies. Although transplant and surgical resection offer the best clinical outcomes, a limited number of patients are amenable to these surgical treatment options due to the advanced disease at presentation. Transarterial embolotherapies including conventional transarterial chemoembolization (cTACE), bland transarterial embolization (TAE), drug-eluting beads transarterial chemoembolization (DEB-TACE) and selective internal radiation therapy (SIRT) with Yttrium 90 (<sup>90</sup>Y) have played an increasingly important role for these patients with unresectable HCC. With a better understanding of different transarterial embolotherapies, more personalized and precise treatment should be implemented for these patients with unresectable HCC. In this review, the updated evidence on the current role of each embolotherapy in the treatment of HCC is summarized. (Clin Mol Hepatol 2017;23:265-272)
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Statistical studies of trough at middle latitudes observed by DMSP F15
박사라,길효섭,김관혁,Park, Sarah,Kil, Hyosub,Kim, Khan-Hyuk 한국천문학회 2012 天文學會報 Vol.37 No.2
The middle-latitude ionization trough, the plasma density depletion in the subauroral region, has been extensively studied since its discovery in the 1960s. Our knowledge of the variability of the trough is mostly based on the observations in the northern hemisphere. Recently, the COSMIC observations enabled the investigation of the trough in both hemispheres at all local time. However, the investigation was limited to the period of the low solar activity. In this study, we investigate the variability of the trough location and morphology with local time, solar cycle, magnetic activity, and interplanetary magnetic field. For this purpose, we analyze the DMSP F15 data acquired during 2000-2010.
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