http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Sara Kashef (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
The Relationship Between Serum 25 Hydroxy Vitamin D Levels and Asthma in Children
Soheila Alyasin,Tooba Momen,Sara Kashef,Abbass Alipour,Reza Amin 대한천식알레르기학회 2011 Allergy, Asthma & Immunology Research Vol.3 No.4
Purpose: Asthma and other allergic disorders have increased over the past decades in nearly all nations. Many studies have suggested the role of vitamin D deficiency in both T-helper1 and T-helper2 diseases; however, the association between vitamin D, allergy, and asthma remains uncertain. In this study, the associations of 25-hydroxy vitamin D3 levels with asthma and with the severity of asthma were evaluated. Methods: This cross-sectional study was conducted on 50 asthmatic children and 50 healthy controls aged 6–18 years. Serum 25-hydroxy vitamin D3 levels were determined and compared between the two groups. The relationship between serum vitamin D levels and pulmonary function test outcomes and eosinophil counts were examined in asthmatic patients. Results: Univariate analysis of the relationship between asthma and vitamin D showed that decreased vitamin D levels were associated with significantly increased odds of asthmatic state (P=0.002). In a multivariate analysis after adjustment for age, body mass index, and sex, the relationship between vitamin D and asthma increased. In asthmatic patients, 25-hydroxy vitamin D levels had direct and significant correlations with both predicted FEV1 (R2=0.318; P=0.024) and FEV1/FVC (R2=0.315; P=0.026). There were no associations between vitamin D level and eosinophil counts, duration of disease, and the number of hospitalization or unscheduled visits in the previous year (P>0.05). Conclusions: These results showed that serum 25-hydroxy vitamin D levels were inversely associated with asthma, and there was a direct and significant relationship between vitamin D levels and pulmonary function test outcomes in asthmatic children. An interventional study in asthmatic patients with low serum vitamin D concentration may establish a causal relationship between asthma and vitamin D.
-
( Reza Amin ),( Mohammad Hadi Imanieh ),( Sara Kashef ),( Seyed Mohsen Dehghani ),( Kiumehr Batebi ),( Issah Gakurya ),( Davood Mehrabani ) 대한소화기학회 2007 SIDDS Vol.9 No.-
Background/Aims: Non-steroidal anti-inflammatory drugs (NSAIDs) remain as the initial approach to the pharmacologic management in juvenile rheumatoid arthritis (JRA). Gastrointestinal (GI) damage associated with NSAIDs is common in adults, but there are few studies available in children. This study was done to determine the GI complications of NSIDs in a cohort of JRA patients by endoscopy. Methods: Twenty-one patients with JRA who were using NSAIDs for at least 3 months were assessed clinically and by endoscopy. Results: The mean age of the patients was 9.8 years (11 female). GI symptoms were found in 42.9% of patients: 33.4% abdominal pain and 9.5% vomiting. Macroscopic endoscopic lesions were found in 85.7% and infection of Helicobacter pylori (Hp) in 14.3% of cases. Conclusions: Our data show that patients using NSAIDs have frequent GI damage without any relation to the duration of treatment. The number of children who had GI damage without any clinical complaint was high. Also we found that there is no significant relationship between the duration of drug use and the GI complaints, and no relation between duration and GI complaints to upper GI tract endoscopic lesions. The possibility of GI derangements with NSAIDs in pediatric age group is high. Close monitoring of symptoms and prevention measures is suggested.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
