Helicobacter pylori Infection and Dietary Factors Act Synergistically to Promote Gastric Cancer

Raei, Negin,Behrouz, Bahador,Zahri, Saber,Latifi-Navid, Saeid Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3

However, the incidence of gastric cancer (GC) has been decreased in past decades; GC is the second cause of cancer related death in the world. Evidence has illustrated that several factors including Helicobacter pylori (H. pylori) infection, host genetics, and environmental factors (smoking and particularly diet) may play a crucial role in gastric carcinogenesis. It has been demonstrated that high consumption of fresh fruits, vegetables, high level of selenium and zinc in drinking water, sufficient iron, and cholesterol protect against GC, while; smoked, pickled, and preserved foods in salt, and nitrites increase the risk of GC. Epidemiological studies have also proved that H. pylori infection and a high salt diet could independently induce atrophic gastritis and intestinal metaplasia. Recently, studies have been demonstrated that dietary factors directly influence H. pylori virulence. The use of appropriate diet could reduce levels of H. pylori colonization or virulence and prevent or delay development of peptic ulcers or gastric carcinoma. This is attractive from a number of perspectives including those of cost, treatment tolerability, and cultural acceptability. This review will describe new insights into the pathogenesis of H. pylori in relation to environmental factors, especially dietary, not only to find the developed means for preventing and treating GC, but also for understanding the role of chronic inflammation in the development of other malignancies.

Resistive Switching Memory Based on Bioinspired Natural Solid Polymer Electrolytes

Raeis Hosseini, Niloufar,Lee, Jang-Sik American Chemical Society 2015 ACS NANO Vol.9 No.1

<P>A solution-processed, chitosan-based resistive-switching memory device is demonstrated with Pt/Ag-doped chitosan/Ag structure. The memory device shows reproducible and reliable bipolar resistive switching characteristics. A memory device based on natural organic material is a promising device toward the next generation of nonvolatile nanoelectronics. The memory device based on chitosan as a natural solid polymer electrolyte can be switched reproducibly between high and low resistance states. In addition, the data retention measurement confirmed the reliability of the chitosan-based nonvolatile memory device. The transparent Ag-embedded chitosan film showed an acceptable and comparable resistive switching behavior on the flexible plastic substrate as well. A cost-effective, environmentally benign memory device using chitosan satisfies the functional requirements of nonvolatile memory operations.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2015/ancac3.2015.9.issue-1/nn5055909/production/images/medium/nn-2014-055909_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn5055909'>ACS Electronic Supporting Info</A></P>

Resistive switching memory using biomaterials

Raeis-Hosseini, N.,Lee, J. S. Springer Science + Business Media 2017 JOURNAL OF ELECTROCERAMICS Vol.39 No.1

<P>Resistive switching memory (ReRAM) is emerging as a developed technology for a new generation of non-volatile memory devices. Natural organic biomaterials are potential elements of environmentally-benign, biocompatible, and biodegradable electronic devices for information storage and resorbable medical implants. Here, we highlight progress in exploiting biomaterials to fabricate a special category of bio-nanoelectronic memories called biodegradable resistive random access memory (bio-ReRAM). Bio-ReRAMs are beneficial because they are non-toxic and environmentally benign. Various types of biomaterials with their chemical compound, bio-ReRAM device design and structure, their relevance resistive switching (RS) behavior, and conduction mechanism are considered in detail. Particularly, we report physically-transient devices, their corresponding switching mechanism, and their dissolution by immersion in water. Finally, we review recent progress in the development of various types of flexible bio-ReRAMs, focusing on their flexibility and reliability as bendable nanoelectronics. Because most of these devices are candidates to become wearable, skin-compatible, and even digestible smart electronics, we discuss the future improvement of natural materials and the perspective of novel bio-ReRAMs.</P>

Helicobacter pylori cag Pathogenicity Island cagL and orf17 Genotypes Predict Risk of Peptic Ulcerations but not Gastric Cancer in Iran

Raei, Negin,Latifi-Navid, Saeid,Zahri, Saber Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15

Background: Gastric cancer (GC) is the third most common cancer regarding mortality in the world. The cag pathogenicity island (PAI) of Helicobacter pylori which contains genes associated with a more aggressive phenotype may involve in the pathogenesis of gastrointestinal disease. We here aimed to examine the associations of cagH, cagL, orf17, and cagG genotypes of H. pylori cag PAI with severe gastrointestinal disease. Materials and Methods: A total of 242 H. pylori strains were genotyped. Histopathological examination and classification of subjects were performed. Results: The frequencies of the cagH, cagL, cagG, and orf17 genotypes were 40/54 (74.1%), 53/54 (98.1%), 38/54 (70.4%), and 43/54 (79.6%), respectively, in patients with peptidic ulceration (PU),while in the control group, the frequencies were 87/147 (59.6%) for cagH, 121/146 (82.9%) for cagL, 109/146 (74.7%) for cagG, and 89/146 (61.0%) for orf17. The results of simple logistic regression analysis showed that the cagL and orf17 genotypes were significantly associated with an increased risk of PU not GC; the ORs (95% CI) were 10.950 (1.446-82.935), and 2.504 (1.193-5.253), respectively. No significant association was found between the cagH and cagG genotypes and the risk of both the PU and the GC in Iran (P>0.05). Finally, multiple logistic regression analysis showed that the cagL genotype was independently and significantly associated with the age-and sex-adjusted risk for PU; the OR (95% CI) was 9.557 (1.219-17.185). Conclusions: We conclude that the orf17 and especially cagL genotypes of H. pylori cag PAI could be factors for risk prediction of PU, but not GC in Iran.

Controlling the Resistive Switching Behavior in Starch-Based Flexible Biomemristors

Raeis-Hosseini, Niloufar,Lee, Jang-Sik American Chemical Society 2016 ACS APPLIED MATERIALS & INTERFACES Vol.8 No.11

<P>Implementation of biocompatible materials in resistive switching memory (ReRAM) devices provides opportunities to use them in biomedical applications. We demonstrate a robust, nonvolatile, flexible, and transparent ReRAM based on potato starch. We also introduce a biomolecular memory device that has a starch chitosan composite layer. The ReRAM behavior can be controlled by mixing starch with chitosan in the resistive switching layer. Whereas starch-based biomemory devices which show abrupt changes in current level; the memory device with mixed biopolymers undergoes gradual changes. Both devices exhibit uniform and robust programmable memory properties for nonvolatile memory applications. The explicated source of the bipolar resistive switching behavior is assigned to formation and rupture of carbon-rich filaments. The gradual set/reset behavior in the memory device based on a starch chitosan mixture makes it suitable for use in neuromorphic devices.</P>

Impact of simulated cigarette excise tax increase on its consumption in Iran

Behzad Raei,Sara Emamgholipour Sefiddashti,Amirhossein Takian,Mehdi Yaseri,Ghahreman Abdoli 한국역학회 2020 Epidemiology and Health Vol.42 No.-

OBJECTIVES: To assess the impact of a simulated tax-induced cigarette price increase on its consumption by different expenditure clusters in Iran. METHODS: Employing consecutive cross sections for cigarette consumption, a two-part model was applied for different expenditure groups. RESULTS: A 75% price increase in cigarettes noticeably— as is common in some countries with strong tobacco control policies—reduces current consumption in all five social classes, causing nearly 8% of current male smokers to quit or not to start. CONCLUSIONS: Findings of the current study suggest that Iranian policy makers go through to implement tobacco taxation policies to control smoking prevalence, which in turn might lead to a reduction in national healthcare expenditures as well as enhance the global community’s capacity to meet Sustainable Development Goals.

Evaluation of a Dietary Organic Selenium Supplement at Different Dietary Protein Concentrations on Growth Performance, Body Composition and Antioxidative Status of Broilers Reared under Heat Stress

Khajali, Fariborz,Raei, Ali,Aghaei, Ali,Qujeq, Dordi Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.4

Three hundred chicks were randomly assigned among four treatments to evaluate the effect of an organic selenium supplement at various levels of dietary protein. Two levels of supplemental selenium (0 and 0.3 mg/kg) from zinc-L-selenomethionine were tested at two levels of dietary protein (normal and reduced) in a completely randomized design with $2{\times}2$ factorial layout. The experiment lasted up to 49 d of age during which all birds were exposed to $31{\pm}1^{\circ}C$. The effects of selenium or its interaction with CP on growth performance and carcass characteristics were not significant. However, feeding the reduced-CP diet decreased weight gain in the starting period and increased liver and abdominal fat weights relative to body weight. Ferric reducing ability of plasma (FRAP) was not significantly affected by dietary CP and Se or their interaction though FRAP values were numerically higher in the Se-supplemented group. Dietary CP content did not affect the activity of plasma glutathione peroxidase (GSHPx), though Se significantly elevated plasma GSHPx activity. The interaction of CP and Se was not significant for FRAP and plasma GSHPx activity.

Design of the Auto Gain Control amplifier based on a resistance modeling of the MOSFET for a distance accuracy of the ToF LiDAR

Youngjoon Cho,Hamidreza Raei,Kyihwan Park 제어로봇시스템학회 2021 제어로봇시스템학회 국제학술대회 논문집 Vol.2021 No.10

ToF(Time of Flight) LiDAR detects the target distance by measuring the timing difference of the pulsed laser beam to the target and received signal. The intensity of the received signal varies with a number of factors. The measured timing can be vary depending on the different magnitude of the signals. It is required to control the amplifying gain to ensure accurate distance measurement with wide range of intensity. In this work, the distance accuracy is investigated when TDC measures the pulse signals. The electronic characteristic of MOSFET is treated and transformed to use it as a variable resistor. Auto Gain Control method is introduced by implementing MOSFET which has a variable resistance characteristics. As a result, simulations are carried out to investigate the AGC operation. The limitation and additional frequency issues will be treated for a next work.

Effects of catalyst preparation methods on the performance of La2MMnO6 (M=Co, Ni) double perovskites in catalytic combustion of propane

Hamidreza Roozbahani,Sarah Maghsoodi,Behrouz Raei,Amirhossein Shahbazi Kootenaei,Zoha Azizi 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.3

La2MMnO6 (M=Co, Ni) dual perovskite oxides were synthesized by sol-gel and gel-combustion methods and tested for the total oxidation of propane. The synthesized catalysts were characterized by TPR, XRD, ICP, SEM, TEM, H2-TPR and O2-TPD techniques. The preparation method had a significant effect on the physicochemical properties of samples. The XRD spectra resulting from the synthesized samples revealed the formation of single-phase perovskite structure. The largest BET specific surface area related to the La2NiMnO6 perovskite synthesized by the gelcombustion method was obtained as 35m2g1 after calcination at 500 oC. Based on the findings, the catalysts synthesized by the gel-combustion method showed an increase in specific surface area, oxygen capacity, reducibility and oxygen mobility compared to those synthesized by the sol-gel method. Accordingly, these catalysts revealed a better performance. The acquired results also showed that the presence of Ni improved the catalytic activity compared to Co. The La2NiMnO6 perovskite synthesized by the gel-combustion method with the T90 equal to 415 oC was found to be the most active catalyst, while the La2CoMnO6 double perovskite synthesized by the sol-gel method with the T90 equal to 474 oC demonstrated the lowest activity.

Descriptive Study of Occupational Accidents and their Causes among Electricity Distribution Company Workers at an Eight-year Period in Iran

Rahmani, Abdolrasoul,Khadem, Monireh,Madreseh, Elham,Aghaei, Habib-Allah,Raei, Mehdi,Karchani, Mohsen Occupational Safety and Health Research Institute 2013 Safety and health at work Vol.4 No.3

Background: Occupational accidents are unplanned events that cause damage. The socio-economic impacts and human costs of accidents are tremendous around the world. Many fatalities happen every year in workplaces such as electricity distribution companies. Some electrical injuries are electrocution, electric shock, and burns. This study was conducted in an electricity distribution company (with rotational 12-hour shift work) in Iran during an 8-year period to survey descriptive factors of injuries. Methods: Variables collected included accident time, age of injured worker, employment type, work experience, injury cause, educational background, and other information about accidents. Results: Results indicated that most of the accidents occurred in summer, and 51.3% were during shift work. Worker negligence (malpractice) was the cause of 75% of deaths. Type of employment had a significant relationship with type of injuries (p < 0.05). Most injuries were electrical burns. Conclusion: High rate of accidents in summer may be due to the warm weather or insufficient professional skills in seasonal workers. Shift workers are at risk of sleep complaints leading to a high rate of work injuries. Acquiring knowledge about safety was related to job experiences. Temporary workers have no chance to work all year like permanent workers, therefore impressive experiences may be less in them. Because the lack of protective equipment and negligence are main causes of accidents, periodical inspections in workshops are necessary.