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Princy, J. Darwin,Shanmugapriya, S. Korea Institute of Construction Engineering and Ma 2017 Journal of construction engineering and project ma Vol.7 No.3
Preeminent performance of construction industry are unattainable with poor productivity resulting in time and cost over runs. Enhancement in productivity cannot be achieved without identifying and analyzing factors that adversely affect productivity. The objective therefore is to propose a productivity analysis model to quantify the probability of effect of factors influencing productivity by using fuzzy logic incorporated with relative importance index method, for various types of construction projects. To achieve this objective, a questionnaire survey was carried out targeting respondents of Indian construction industry, from four distinct projects, namely, residential, commercial, infrastructure and industrial projects. Based on questionnaire administered, the relative importance and ranks of factors demonstrated using relative importance index method. Probability assessment model to analyze productivity was then developed by using Fuzzy Logic Toolbox of MATLAB. The applicability of the proposed model was tested in seven construction projects and the probability of impact of factors on productivity evaluated. The results of application of model in the construction firms infers that the most contributing factor groups for most of the projects were discerned to be manpower, motivation and time group.
Needle-Free Immunization with Chitosan-Based Systems
Singh, Bijay,Maharjan, Sushila,Sindurakar, Princy,Cho, Ki-Hyun,Choi, Yun-Jaie,Cho, Chong-Su MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.11
<P>Despite successful use, needle-based immunizations have several issues such as the risk of injuries and infections from the reuse of needles and syringes and the low patient compliance due to pain and fear of needles during immunization. In contrast, needle-free immunizations have several advantages including ease of administration, high level of patient compliance and the possibility of mass vaccination. Thus, there is an increasing interest on developing effective needle-free immunizations via cutaneous and mucosal approaches. Here, we discuss several methods of needle-free immunizations and provide insights into promising use of chitosan systems for successful immunization.</P>
Ravichandiran, Palanisamy,Subramaniyan, Sivakumar Allur,Bella, Antony Paulraj,Johnson, Princy Merlin,Kim, Ae Rhan,Shim, Kwan Seob,Yoo, Dong Jin American Chemical Society 2019 ANALYTICAL CHEMISTRY - Vol.91 No.15
<P>A phenoxazine-based fluorescence chemosensor <B>4PB</B> [(4-(<I>tert</I>-butyl)-<I>N</I>-(4-((4-((5-oxo-5<I>H</I>-benzo[<I>a</I>]phenoxazin-6-yl)amino)phenyl)sulfonyl)phenyl)benzamide)] was designed and synthesized by a simple synthetic methods. The <B>4PB</B> fluorescence chemosensor selectively detects Ba<SUP>2+</SUP> in the existence of other alkaline metal ions. In addition, <B>4PB</B> showed high selectivity and sensitivity for Ba<SUP>2+</SUP> detection. The detection limit of <B>4PB</B> was 0.282 μM and the binding constant was 1.0 × 10<SUP>6</SUP> M<SUP>-1</SUP> in CH<SUB>3</SUB>CN/H<SUB>2</SUB>O (97.5:2.5 v/v, HEPES = 1.25 mM, pH 7.3) medium. This chemosensor functioned through the intramolecular charge transfer (ICT) mechanism, which was further confirmed by DFT studies. Live cell imaging in MCF-7 cells confirmed the cell permeability of <B>4PB</B> and its capability for specific detection of Ba<SUP>2+</SUP> in living cells.</P> [FIG OMISSION]</BR>
Danish Ather,J. Prisca Mary,Pooja Singh,Kanika Garg,T.R. Priyadharshini,B. Anni Princy,Mohit Tiwari 대한전자공학회 2024 IEIE Transactions on Smart Processing & Computing Vol.13 No.2
Wireless sensor network (WSN) applications are added day by day owing to numerous global uses (by the military, for monitoring the atmosphere, in disaster relief, and so on). Here, trust management is a main challenge. Sensor nodes are important in wireless sensor networks, but they are easily depleted because of their short lifespan from continuous sensing activity and low battery capacity. So efficient energy utilization is a challenging task in a WSN. To minimize energy loss, clustering with an optimum path selection process is needed to retain energy in sensor nodes. This manuscript proposes multi-objective Pelican Optimization Algorithm (POA) routing to maintain energy efficiency and minimize transmission distances in wireless sensor networks. A cluster head (CH) is selected by using a Separable Convolution Neural Network (SCNN). Simulation outcomes prove the proposed technique attains 22.3% and 25.04% improvements in energy consumption when compared to the Multi-Objective CH Energy-aware Optimized Routing Approach at WSN (MOCH-EORA-WSN) and Multiple Optimum Cluster Head Multi-Objective Grasshopper Optimization with Harmony-search at WSN (MOCH-MOGOH-WSN), respectively.
A Meningioma With Extensive Peritumoral Edema Mimicking Metastatic Brain Tumor: A Case Report
( Princi D. Demaisip ),( Dan Neftalie Juangco ),( Nic Junn C. Tambal ),( Nina Alvarez ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2023 Brain Tumor Research and Treatment Vol.11 No.2
Meningioma is the most common brain tumor among all histologically reported malignant and non-malignant tumors of the central nervous system. Angiomatous meningioma is one of the subtypes of meningioma that is rarely reported. In this paper, we present a case of a 67-year-old female patient who sought consultation due to seizure, cognitive decline, and parkinsonism. Contrast-enhanced MRI showed a well-defined tumor in the left frontal lobe convexity with extensive perilesional edema. A tumor excision was done and histopathology studies revealed an angiomatous meningioma subtype. This case is reportable because angiomatous meningioma is a recognized rare entity. It is important to share this entity with other medical professionals and start to consider this condition in differential diagnosis when diagnosing a patient with an intracranial mass with an extensive peritumoral edema. Furthermore, the patient’s unusual presentation of parkinsonian features and its occurrence with colorectal cancer history suggest a possible association between these conditions.
GSTT1 Null Genotype Distribution in the Kumaun Region of Northern India
Bag, Arundhati,Upadhyay, Saloni,Jeena, Lalit M.,Pundir, Princi,Jyala, Narayan S. Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1
Glutathione S-transferases (GSTs) constitute a multigene family of multifunctional phase II metabolic enzymes. GSTT1, an important member of this group has a wide range of substrates including carcinogens. Total homozygous deletion or null genotype resulting in total lack of enzyme activity exists in populations for this enzyme. Since the null genotype may contribute to lower detoxification of carcinogens, this genotype is expected to increase cancer risk. The frequency of the GSTT1 null genotype is known to vary significantly among populations. However, little is known about its distribution in the hilly Kumaun region of northern India. Therefore, in this study, we determined the prevalence of the GSTT1 null polymorphism in the Kumaun popilation by conducting duplex PCR in 365 voluntary healthy individuals. The GSTT1 null genotype was detected in 18.4% of the individuals. Since GSTs play significant role in xenobiotic metabolism, the present data on GSTT1 genotype distribution should contribute in understanding genetic association with cancer risk in this understudied population.
P. G. Gucciardi,A. Favaloro,A. Pisani,G. Cutroneo,P. Princi 한국물리학회 2005 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.47 No.1
The -Sarcoglycan and the f-actin are two protein systems with structural and signaling functions, allowing interaction between muscle fibers and extra cellular matrix. Although numerous studies have been conducted on these systems, their localization and distribution patterns along the nonjunctional sarcolemma are not clear. In this paper we first apply fluorescence Near-Field Optical Microscopy to study this problem on human muscle cells, taking advantage of the enhanced spatial resolution of this technique. Samples of human muscle (vastus lateralis) are analyzed, obtained during orthopedic surgery from subjects not affected by neuromuscular diseases. Following the protocol used to carry out indirect immunofluorescence, TRITC-conjugated IgG anti-mouse in goat has been used as the first fluorochrome and, after saturation of residual free binding sites, sections have been incubated with a second antibody conjugated with FITC fluorochrome. Samples, first studied by fluorescence confocal microscopy, show that all tested proteins have a localized,periodic (costameric) spatial distribution. Subsequent SNOM studies have been aimed both to the single localization of the proteins along the cell membrane, and to the double localization of the proteins with respect to each other. The typical costameric band structure has been evidenced in both the fluorescence and the topography maps of dry cells, with a period of 2 μm for both proteins. A careful correlation between the opography (not available in confocal microscopy) and the fluorescence information permits to draw conclusions on the spatial localization of the two proteins, confirming the results found in confocal microscopy.