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      • KCI등재

        Performance evaluation and optimization of nano boric acid powder weight percentage mixed with vegetable oil using the Taguchi approach

        P. N. L. Pavani,R. Pola Rao,S. Srikiran 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.11

        Turning, which is a widely employed method of metal removal process in manufacturing industries, generates many temperatures becauseof the increase in cutting forces. In view of the high temperatures developed in the process, tools deteriorate, and so good surfacequality is difficult to achieve. Lubrication becomes critical to minimize the forces and temperatures generated during the process. In thepresent work, boric acid powder is used as a solid lubricant, which is mixed with vegetable oils such as coconut oil and soybean oil inturning process. The results indicate that there is a considerable improvement in the machining performance with boric acid assistedMQL in machining compared with dry and wet machining. Taguchi method is a powerful problem solving technique for improving processperformance, yield, and productivity. Combining the speed, feed, and depth of cut is helpful. In the present study, the combinationusing Taguchi DOE was taken as factors, levels, and 32 experimental layouts are framed. The current study attempts to study the variationsin tool temperature; cutting forces and surface roughness of the machined component under various machining conditions to findthe optimum weight percentage of the solid lubricant used.

      • KCI등재

        α-lipoic acid protects testis and epididymis against linuron-induced oxidative toxicity in adult rats

        Prathima P.,Venkaiah K.,Daveedu T.,Pavani R.,Sukeerthi S.,Gopinath M.,Sainath Sri Bhashaym 한국독성학회 2020 Toxicological Research Vol.36 No.4

        Linuron is well known for its antiandrogenic property. However, the effects of linuron on testicular and epididymal pro- and antioxidant status are not well defined. On the other hand, α-lipoic acid is well known as universal antioxidant. Therefore, the purpose of this study was twofold: firstly to investigate whether linuron exposure alters antioxidant status in the testis and epididymis of rats and if so, whether the supplementation of α-lipoic acid mitigates linuron-induced oxidative toxicity in rats. To address this question, α-lipoic acid at a dose of 70 mg/Kg body weight (three times a week) was administered to linuron exposed rats (10 or 50 mg/Kg body weight, every alternate day over a period of 60 days), and the selected reproductive endpoints were analyzed after 60 days. Respective controls were maintained in parallel. Linuron at selected doses reduced testicular daily sperm count, and epididymal sperm count, sperm motility, sperm viability, and number of tail coiled sperm, reduced activity levels of 3β- and 17β-hydroxysteroid dehydrogenases, decreased expression levels of StAR mRNA, inhibition of testosterone levels, and elevated levels of testicular cholesterol in rats over controls. Linuron intoxication deteriorated the structural integrity of testis and epididymis associated with reduced the reproductive performance over controls. Conversely, α-lipoic acid supplementation enhanced sperm quality and improved the testosterone synthesis pathway in linuron exposed rats over its respective control. Administration of α-lipoic acid restored inhibition of testicular and epididymal enzymatic (superoxide dismutase, catalase, glutathione reductase, glutathione peroxidise) and non-enzymatic (glutathione content), increased lipid peroxidation and protein carbonyl content produced by linuron in rats. α-lipoic acid supplementation inhibited the expression levels of testicular caspase-3 mRNA levels and also its activity in linuron treated rats. To summate, α-lipoic acid-induced protection of reproductive health in linuron treated rats could be attributed to its antioxidant, and steroidogenic properties.

      • SCIESCOPUSKCI등재

        Dietary Calcium and Non-phytin Phosphorus Interaction on Growth, Bone Mineralization and Mineral Retention in Broiler Starter Chicks

        Rao, S.V. Rama,Raju, M.V.L.N.,Reddy, M.R.,Pavani, P.,Sunder, G. Shyam,Sharma, R.P. Asian Australasian Association of Animal Productio 2003 Animal Bioscience Vol.16 No.5

        An experiment was conducted to study the requirement of calcium (Ca) and non-phytin phosphorus (NPP) in commercial broilers during starter phase. Seven hundred and twenty day-old Vencob male broiler chicks were randomly distributed into 144 stainless steel battery brooders, 5 birds in each. Four levels each of Ca (6, 7, 8, and 9 g/kg) and NPP (3, 3.5, 4, and 4.5 g/kg diet) were fed in a factorial design in a corn-soya basal diet. Levels of dicalcium phosphate and oyster shell grit were adjusted to obtain the desired levels of Ca and NPP. Each diet was fed ad libidum to chicks in 9 battery brooders from one d to 21 d of age. Body weight gain and feed intake were depressed (p<0.01) by increasing the dietary Ca level (8 and 9 g/kg) at lower levels of NPP (3 and 3.5 g/kg diet). The growth depression observed at lower NPP level was alleviated by reducing the Ca content to 6 g/kg diet. The tibia ash content and tibia breaking strength increased with increase in both Ca (>6 g/kg) and NPP (>3 g/kg) levels. The leg abnormality score decreased (p<0.01) with increase in NPP content in the diet at all levels of Ca tested. The serum Ca and inorganic P levels were increased with increase in the level of the respective mineral in the diet, but the serum concentration of Ca and P were inversely related to the level of NPP and Ca, respectively /kg diet. In general, the excretion of macro minerals (Ca, and P), and micro minerals {zinc (Zn), manganese (Mn), iron (Fe), and copper (Cu)} was significantly lower at lower levels of Ca and NPP tested (6 and 3 g/kg diet, respectively). The mineral excretion increased with increase in dietary Ca and NPP levels, more conspicuously at the disproportionate ratio of these minerals (>2:1, Ca and NPP). Similarly, the retention of Zn, Mn, and Fe in liver was significantly higher (p<0.01) at lower levels of Ca and NPP tested. Results from this study indicate that the commercial broilers do not require more than 3 g NPP and 6g Ca/kg diet during starter phase (up to 21 d of age) for optimum weight gain, feed efficiency and utilization of Ca, P, Zn, Mn, Fe and Cu. However, the requirements of these minerals for optimum bone mineralization were higher than the levels suggested above.

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