COMMON FIXED POINTS FOR A RATIONAL INEQUALITY UNDER WEAK COMPATIBLE MAPS OF TYPE (A) (DEDICATED TO THE LATE P. V. LAKSHMAIAH)

Murthy, P.P.,Olaleru, J.O. The Youngnam Mathematical Society 2009 East Asian mathematical journal Vol.25 No.1

In this paper, we present a unique common xed point theorem under weak compatible mappings of type(A), which extends and generalizes a result of Achari [1].

Common fixed points for a rational inequality under weak compatible maps of type (A) (Dedicated to the late P. V. Lakshmaiah)

P. P. Murthy,J. O. Olaleru 영남수학회 2009 East Asian mathematical journal Vol.25 No.1

In this paper, we present a unique common fixed point theorem under weak compatible mappings of type(A), which extends and generalizes a result of Achari [1].

Fracture energy and tension softening relation for nanomodified concrete

A. Ramachandra Murthy,P. Ganesh,S. Sundar Kumar,Nagesh R. Iyer 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.54 No.6

This paper presents the details of size independent fracture energy and bi-linear tension softening relation for nano modified high strength concrete. Nano silica in powder form has been used as partial replacement of cement by 2 wt%. Two popular methods, namely, simplified boundary effect method of Karihaloo et al. (2003) and RILEM (1985) fracture energy with P-δ tail correction have been employed for estimation of size independent fracture energy for nano modified high strength concrete (compressive strength ranges from 55 MPa to 72 MPa). It is found that both the methods gave nearly same values, which is an additional evidence that either of them can be employed for determination of size independent fracture energy. Bi-linear tension softening relation corresponding to their size independent fracture energy has been constructed in an inverse manner based on the concept of non-linear hinge from the load-crack mouth opening plots of notched three-point bend beams.

Perception and Practices on Screening and Vaccination for Carcinoma Cervix among Female Healthcare Professional in Tertiary Care Hospitals in Bangalore, India

Swapnajaswanth, M.,Suman, G.,Suryanarayana, S.P.,Murthy, N.S. Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

Background:Cervical cancer is potentially the most preventable and treatable cancer. Despite the known efficacy of cervical screening, a significant number of women do not avail themselves of the procedure due to lack of awareness. Objectives: This study was conducted to elicit information on the knowledge, attitude and practice (KAP) regarding screening (Pap test) and vaccination for carcinoma cervix among female doctors and nurses in a tertiary care hospital in Bangalore and to assess barriers to acceptance of the Pap test. Materials and Methods: A cross-sectional, descriptive study was conducted with semi-structured, self-administered questionnaire among female health professionals. The study subjects were interviewed for KAP regarding risk factors for cancer cervix, Pap test and HPV vaccination for protection against carcinoma cervix. Results: Higher proportion of doctors 45 (78.9%) had very good knowledge as compared to only 13 (13.3%) of the nurses, about risk factors for cancer cervix and Pap test (p=0.001). As many as 138(89.6%) of the study subjects had favorable attitude towards Pap test and vaccination, but 114 (73.6%) of the study subjects never had a Pap test and the most common reason 35 (31%) for not practicing was absence of disease symptoms. Conclusions: In spite of good knowledge and attitudes towards cancer cervix and Pap test being good, practice remained low among the study subjects and most common reasons for not undergoing Pap test was absence of disease symptoms. The independent predictors of ever having a Pap test done was found to be the occupation and duration of married life above 9yrs. Hence there is a strong need to improve uptake of Pap test by health professionals by demystifying the barriers.

Antitumor effect of Careya arborea against Ehrlich ascites carcinoma with reference to lipid peroxidation and enzymatic and non enzymatic antioxidant system in Swiss albino mice

R Sambath Kumar,T Sivakumar,V Senthil,N Venkateswara Murthy,V Balasubramaniam,R Kanaga Sabi,R. Shanmuga Sundram,P Perumal,U K Mazumder,M Gupta 경희대학교 융합한의과학연구소 2008 Oriental Pharmacy and Experimental Medicine Vol.8 No.2

The methanol extract of stem barks of Careya arborea Roxb. (MECA) (Family- Myrtaceae) was evaluated for antitumor activity and antioxidant status against Ehrlich’s Ascites Carcinoma (EAC) bearing Swiss albino mice. After 24 h of tumor inoculation the MECA was administered at the doses of 50, 100 and 200 mg/kg body weight/mice/day for 14 days. After the last dose and 18 h fasting mice were sacrificed. The effect of MECA on the growth of transplantable murine tumor, life span of EAC bearing hosts, hematological profiles, serum and liver biochemical parameters were estimated. The MECA showed significant (P < 0.01) decrease in ascites volume, packed cell volume and viable cell count and prolonged the life span of EAC tumor bearing mice. Hematological profiles reverted to more or less normal levels in extract treated mice. The MECA also produced protective effect by decreasing the activity of serum enzymes, bilirubin and increase the protein and uric acid levels. MECA significantly (P < 0.05) decreased the levels of lipid peroxidation, while significantly (P < 0.05) increased the levels of glutathione content, vitamin C, vitamin E, superoxide dismutase and catalase CAT. The results indicate that MECA exhibited significant antitumor and antioxidant activity in EAC bearing mice. The methanol extract of stem barks of Careya arborea Roxb. (MECA) (Family- Myrtaceae) was evaluated for antitumor activity and antioxidant status against Ehrlich’s Ascites Carcinoma (EAC) bearing Swiss albino mice. After 24 h of tumor inoculation the MECA was administered at the doses of 50, 100 and 200 mg/kg body weight/mice/day for 14 days. After the last dose and 18 h fasting mice were sacrificed. The effect of MECA on the growth of transplantable murine tumor, life span of EAC bearing hosts, hematological profiles, serum and liver biochemical parameters were estimated. The MECA showed significant (P < 0.01) decrease in ascites volume, packed cell volume and viable cell count and prolonged the life span of EAC tumor bearing mice. Hematological profiles reverted to more or less normal levels in extract treated mice. The MECA also produced protective effect by decreasing the activity of serum enzymes, bilirubin and increase the protein and uric acid levels. MECA significantly (P < 0.05) decreased the levels of lipid peroxidation, while significantly (P < 0.05) increased the levels of glutathione content, vitamin C, vitamin E, superoxide dismutase and catalase CAT. The results indicate that MECA exhibited significant antitumor and antioxidant activity in EAC bearing mice.

Prediction of flexural behaviour of RC beams strengthened with ultra high performance fiber reinforced concrete

Murthy A, Ramachandra,Aravindan, M.,Ganesh, P. Techno-Press 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.65 No.3

This paper predicts the flexural behaviour of reinforced concrete (RC) beams strengthened with a precast strip of ultra-high performance fiber-reinforced concrete (UHPFRC). In the first phase, ultimate load capacity of preloaded and strengthened RC beams by UHPFRC was predicted by using various analytical models available in the literature. RC beams were preloaded under static loading approximately to 70%, 80% and 90% of ultimate load of control beams. The models such as modified Kaar and sectional analysis predicted the ultimate load in close agreement to the corresponding experimental observations. In the second phase, the famous fatigue life models such as Papakonstantinou model and Ferrier model were employed to predict the number of cycles to failure and the corresponding deflection. The models were used to predict the life of the (i) strengthened RC beams after subjecting them to different pre-loadings (70%, 80% and 90% of ultimate load) under static loading and (ii) strengthened RC beams after subjecting them to different preloading cycles under fatigue loading. In both the cases precast UHPFRC strip of 10 mm thickness is attached on the tension face. It is found that both the models predicted the number of cycles to failure and the corresponding deflection very close to the experimental values. It can be concluded that the models are found to be robust and reliable for cement based strengthening systems also. Further, the Wang model which is based on Palmgren-Miner's rule is employed to predict the no. of cycles to failure and it is found that the predicted values are in very good agreement with the corresponding experimental observations.

Meta-analysis of GSTM1 and GSTT1 Polymorphisms and Risk of Nasopharyngeal Cancer

Murthy, Archana Krishna,Kumar, Vinod,Suresh, K.P. Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Background: Studies of associations between genetic polymorphism of glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) with risk of nasopharyngeal cancer (NPC) have generated conflicting results. Thus, a meta-analysis was performed to clarify the effects of GSTM1 and GSTT1 polymorphisms on the risk of developing NPC. Materials and Methods: A literature search in two electronic databases namely PubMed and EMBASE up to December 2012 was conducted and eligible papers were finally selected based on the inclusion and exclusion criteria. The pooled odds ratio (OR) and presence of heterogeneity and publication bias in those studies were evaluated. Results: A total of 9 studies concerning nasopharyngeal cancer were evaluated. Analyses of all relevant studies showed increased NPC risk to be significantly associated with the null genotypes of GSTMI (OR=1.43, 95%CI 1.24-1.66) and GSTT1 (OR=1.28, 95%CI=1.09-1.51). In addition, evidence of publication bias was detected among the studies on GSTM1 polymorphism. Conclusions: This meta-analysis demonstrated the GSTM1 and GSTT1 null genotypes are associated with an increased risk of NPC.

Hierarchical Silicon Nanospikes Membrane for Rapid and High-Throughput Mechanical Cell Lysis

So, Hongyun,Lee, Kunwoo,Seo, Young Ho,Murthy, Niren,Pisano, Albert P. American Chemical Society 2014 ACS APPLIED MATERIALS & INTERFACES Vol.6 No.10

<P/><P>This letter reports an efficient and compatible silicon membrane combining the physical properties of nanospikes and microchannel arrays for mechanical cell lysis. This hierarchical silicon nanospikes membrane was created to mechanically disrupt cells for a rapid process with high throughput, and it can be assembled with commercial syringe filter holders. The membrane was fabricated by photoelectrochemical overetching to form ultrasharp nanospikes in situ along the edges of the microchannel arrays. The intracellular protein and nucleic acid concentrations obtained using the proposed membrane within a short period of time were quantitatively higher than those obtained by routine, conventional acoustic and chemical lysis methods.</P>

Synthesis, Characterization and Bioevaluation of New Tetrahydroquinazolines

Murthy, Y.L.N.,Acharyulu, P.V.N.,Dubey, P.K.,Sundari, T. Tirunala Korean Chemical Society 2008 대한화학회지 Vol.52 No.3

새로운 다섯개의 tetrahydroquinazolines 의 합성과 구조 결정 및 생물학적 평가는 보고 되었다. 최초에 준비된 cyclohexanones는 목표분자를 얻기 위한 synthon으로 사용되어졌다. 이들은 치환된 벤즈알데히드와 결합되어졌고, 얻어진 chalcone은 구아니딘 염산염으로 처리했다. 모든 분자들은 인간세포에 무독하며 상당한 항균성을 보여줬다. The synthesis, characterization and bioevaluation of five new tetrahydroquinazolines was reported. Initially cyclohexanones were prepared and they were used as synthons to get the target molecules. These were condensed with substituted benzaldehydes and the resulting chalcones were treated with guanidine hydrochloride . All the molecules were non-toxic to human cells and showed significant antibacterial activity.

Multiple-Load Induction Cooking Application with Three-Leg Inverter Configuration

P. Sharath Kumar,N. Vishwanathan,Bhagwan K. Murthy 전력전자학회 2015 JOURNAL OF POWER ELECTRONICS Vol.15 No.5

Inverter configurations for multiple-load induction cooking applications need development. Inverter configurations for induction cooking applications are used in home appliances based on single coil inverters. For multiple-load configurations, multiple coils are used. They require proper inverters, which provide independent control for each load and have fewer components. This paper presents a three-leg inverter configuration for three load induction cooking applications. Each induction coil powers one induction cooking load. This configuration operates with constant switching frequency and powers individual loads. The output power of the required load is controlled with a phase-shift control technique. This configuration is simulated and experimentally tested with three induction loads. The simulation and experimental results are in good agreement. This configuration can be extended to more loads.