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Brief review of the field test and application of a superconducting fault current limiter
Hyun, Ok-Bae The Korea Institute of Applied Superconductivity a 2017 한국초전도저온공학회논문지 Vol.19 No.4
This article reviews the recent activities of field testing and application of superconducting fault current limiters (SFCL) based on high-temperature superconductors (HTS). The review particularly focuses on the trends in the field tests in terms of the technical aspects and commercial activities of the SFCLs. Stimulated by the discovery of HTS, numerous research and development activities have been conducted worldwide for SFCLs operating from distribution voltages to transmission voltages. Different types of SFCLs have been developed and field-tested. Consequently, more than 20 field tests and applications have been performed on real grids worldwide while supplying electric power to the customers. These field tests have not only provided the track records of the operation experiences including the problems and maintenance during operation, but also proved their current limiting capabilities against real faults, rendering this new technology highly viable. Through these activities, the following trends in the status of field testing and application are observed. Resistive-type SFCLs with HTS-coated conductors were dominantly used in the most recent field tests. This implies that the resistive type is technically more mature than the other types. Bus-bar coupling and transformer feeders were the major application locations. It is of importance that most of the field applications were conducted as R&D projects. A relevant change from the R&D stage to the application stage is shown as recently deployed SFCLs are expected to be under long-term operation and commercial service. Here, we review the installation of these SFCLs by substation. This review also discusses the recent activities for their commercial applications.
( Hyun Suk Ahn ),( Sun Hwa Cha ),( Hwa Seon Koo ),( Ju Youn Bae ),( Ji Hee Yoo ),( In Ok Song ),( Hyun Kyoung Ahn ),( Su Jin Hwang ),( Dong Wook Park ),( Kwang Moon Yang ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.7
We aimed to evaluate the effect of prednisolone (PDS) on natural killer cell (NK cell) cytolytic activity in vitro. Methods Blood samples from 74 patients with history of unexplained recurrent spontaneous abortion who elevated peripheral blood NK cell fraction were collected prospectively. Peripheral blood monocytes which containing NK cells were isolated and separated to three different tubes which containing target (K562) cells by the 50:1 effector to target (E:T) ratio. PDS or intravenous immunoglobulin (IVIG) was additionally added to 2 tubes for evaluate their suppressive effect. The percentage killing of target cells was recorded numerically by using flow cytometer and the values between groups were statistically analyzed. Results The mean target cell killing percentage was 40.5% in co-culture tube which was not added PDS or IVIG. In culture experiments which was added IVIG, the killing percentage is reduced to 37.7% which showed no significant differences compared to that of co-cultured tube which was not added PDS or IVIG. But, in experiments with added PDS, the killing percent was reduced to 19.5% and the difference was statistically significant ( P<0.001) compared to that of co-cultured tube which was not added PDS or IVIG. On comparing the reduction in killing percentage of target cells by PDS and IVIG, statistically significant reduction in the PDS coculture was noted ( P<0.005). Conclusion NK cell cytolytic activity is effectively down-regulated by using PDS in vitro. Moreover, the effect of PDS in down-regulation of NK cell cytolytic activity is seems to superior than that of IVIG. But, large scaled in vivo study is needed.
( Hyun Chin Cho ),( Hyun Ju Min ),( Chang Yoon Ha ),( Hyun Jin Kim ),( Tae Hyo Kim ),( Woon Tae Jung ),( Ok Jae Lee ),( In Gyu Bae ) The Editorial Office of Gut and Liver 2009 Gut and Liver Vol.3 No.1
Several cases of Polygonum multiflorum Thunb-induced hepatitis have been reported worldwide. Anthraquinone is an active ingredient of P. multiflorum Thunb. that has been thought to play a role in its hepatotoxicity. Here we report the case of a 34-year-old Korean man who had P. multiflorum Thunb-induced hepatitis and reactivation of pulmonary tuberculosis caused by bone marrow suppression, which developed simultaneously. He was admitted to our hospital with recently developed fatigue and aggravated jaundice. He was a previously healthy man except for the sequelae of pulmonary tuberculosis seen on chest X-ray. He had a 30-day history of ingesting the root of P. multiflorum as a form of liquor and tea. The patient was diagnosed with P. multiflorum Thunb-induced hepatitis after excluding all other potential causes of acute hepatitis. Liver function gradually improved following the total cessation of the consumption of the material. However, he suffered from spiking fever with progressive pancytopenia during the hospital stay. A bone marrow biopsy showed markedly hypocellular marrow, suggesting transient bone marrow suppression, which was probably caused by extrinsic factors such as drugs, toxins, and viral infection. Although he began to complain of a dry cough, repeated sputum investigations revealed positive acid-fast bacillus staining. The fever subsided and pancytopenia improved after treatment for pulmonary tuberculosis. These observations suggest that P. multiflorum Thunb induces both bone marrow suppression and hepatotoxicity. (Gut and Liver 2009;3:52-56)
Bae, Mi-Ok,Choi, Kyung-Ho,Lee, Hu-Jang,Kim, Hyun-Woo,Kim, Jun-Sung,Hwang, Soon-Kyung,Park, Jin-Hong,Cho, Hyun-Sun,Cho, Myung-Haing The Korean Society of Veterinary Science 2004 大韓獸醫學會誌 Vol.44 No.3
When an organism is exposed to various toxicants chronically, reactive oxygen species(ROS) are accumulated and eventually result in several biological effects from gene expression to cell death. In the present study we investigated the oxidative damage of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin(TCDD) and/or benzo(a)pyrene (B(a)P) in C100 cells. C100 cells treated with TCDD(30 nM) and B(a)P($3{\mu}M$) underwent diverse oxidative stress as determined through thiobarbituric acid-reactive substances(TBARS) formation, DNA fragmentation, DNA single strand break(SSB) assay, immunohistochemical staining of 8-hydroxy-2'-deoxyguanosine(8-OHdG), and mRNA expressions of antioxidant enzymatic genes such as Cu/Zn-SOD gene, GPx(glutathione peroxidase 5) gene, and catalase gene. Lipid peroxidation in C100 cells was determined through measuing the formation of TBARS. For theat, the cells were pretreated with TCDD(30 nM) and/or B(a)P($3{\mu}M$) for 0.5, 1, 2 and 4 days. TBARS formation was increased in TCDD(30 nM) and B(a)P($3{\mu}M$) and mixture($30nM\;TCDD+3{\mu}M\;B(a)P$) and positive control treatment groups comparing to the controls. Mixture treatment induced more DNA fragmentation than the single treatment group at day 6. Also, SSB in all treatment groups was clearly observed when compared with the negative control group. As with the expression of antioxidant enzyme, GPx 5mRNA, B(a)P alone and mixture($30nM\;TCDD+3{\mu}M\;B(a)P$) treatment were higher comparing to those of the negative control and TCDD treatment groups. Our results suggest that exposure of C100 cells to mixture of TCDD and B(a)P leads to significant oxidative damage comparing to the exposures to the individual chemicals. Mechanisms of action are discussed. Additional studies are needed to elucidate the detailed mechanism of mixture-induced toxicity.
Cigarette Smoking and Prostate Cancer Risk: Negative Results of the Seoul Male Cancer Cohort Study
Bae, Jong-Myon,Li, Zhong-Min,Shin, Myung-Hee,Kim, Dong-Hyun,Lee, Moo-Song,Ahn, Yoon-Ok Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8
We evaluated cigarette smoking as a risk factor for prostate cancer in a prospective, population-based cohort study. The subjects were 14,450 males among the participants in the Seoul Male Cancer Cohort Study who had at least 1-year follow-up. They were followed up between 1993 and 2008. During the 16-year follow-up period, 87 cases of prostate cancer occurred over the 207,326 person-years of the study. The age-adjusted relative risks of past and current smokers at entry were 0.60 (95%CI: 0.34-1.06) and 0.70 (95%CI: 0.43-1.13), respectively, suggesting that cigarette smoking may not be a risk factor for prostate cancer. The relationship between prostate cancer and other modifiable factors, such as Westernized diet, should be studied with the goal of establishing prevention programs for prostate cancer.
Maritime Wireless Data Communications of Predictive Frequency Hopping Technique
Bae, Sang-Hyun,Lee, Kwang-Ok,Jang, Bong-Seog The Basic Science Institute Chosun University 2012 조선자연과학논문집 Vol.5 No.3
In this paper, For 4th generation wireless communication systems, we propose a method to predict FH patterns in FH-OFDMA systems. OFDM is recognized as a promising modulation technique. Multi-user allocation in OFDM system can use FH that provides the spectrum-spread techniques. If one can generate more predictable FH sequences, then performance of the system can be easily improved. Current random FH and simple adaptive FH methods, however, are not considering predicting FH sequences. In this paper we show that the sampling of the wireless faded signal is not realized as a certain probability nature. With this regard, the proposed predictive FH allocation method is designed to embed the unknown probability models. Simulation study shows that the predictive FH method is more accurately predict FH sequences than the random or simple adaptive FH methods. We will further improve this proposed method to apply QoS control and MAC function development in OFDMA based wireless physical structures, especially maritime wireless data communications.
Hyun Dong-Wook,Lee Jae-Yun,Kim Min-Soo,Shin Na-Ri,Whon Tae Woong,Kim Kyung Hyun,Kim Pil Soo,Tak Euon Jung,Jung Mi-Ja,이준영,Kim Hyun Sik,Kang Woorim,Sung Hojun,Jeon Che Ok,Bae Jin-Woo 한국미생물학회 2021 The journal of microbiology Vol.59 No.8
Viridans group streptococci are a serious health concern because most of these bacteria cause life-threatening infections, especially in immunocompromised and hospitalized individuals. We focused on two alpha-hemolytic Streptococcus strains (I-G2 and I-P16) newly isolated from an ileostomy effluent of a colorectal cancer patient. We examined their pathogenic potential by investigating their prevalence in human and assessing their pathogenicity in a mouse model. We also predicted their virulence factors and pathogenic features by using comparative genomic analysis and in vitro tests. Using polyphasic and systematic approaches, we identified the isolates as belonging to a novel Streptococcus species and designated it as Streptococcus ilei. Metagenomic survey based on taxonomic assignment of datasets from the Human Microbiome Project revealed that S. ilei is present in most human population and at various body sites but is especially abundant in the oral cavity. Intraperitoneal injection of S. ilei was lethal to otherwise healthy C57BL/6J mice. Pathogenomics and in vitro assays revealed that S. ilei possesses a unique set of virulence factors. In agreement with the in vivo and in vitro data, which indicated that S. ilei strain I-G2 is more pathogenic than strain I-P16, only the former displayed the streptococcal group A antigen. We here newly identified S. ilei sp. nov., and described its prevalence in human, virulence factors, and pathogenicity. This will help to prevent S. ilei strain misidentification in the future, and improve the understanding and management of streptococcal infections.
Cigarette Smoking and Risk of Lung Cancer in Korean Men: The Seoul Male Cancer Cohort Study
Bae, Jong-Myon,Lee, Moo-Song,Shin, Myung-Hee,Kim, Dong-Hyun,Li, Zhong-Min,Ahn, Yoon-Ok KOREAN ACADEMY OF MEDICAL SCIENCE 2007 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.22 No.3
<P>Lung cancer is the leading cause of cancer deaths in Korea. The aim of this study was to estimate lung cancer risk of cigarette smoking in Korean men by a 10-yr follow-up prospective cohort study using the primary databases. The number of subjects was 14,272 men, who had full information of smoking habits among participants in the Seoul Male Cancer Cohort Study (SMCC). Total 125,053 person-years were calculated by determining the number of days from the start of follow-up, January 1, 1993, until the date of lung cancer diagnosis, death from another cause, or the end of follow-up, December 31, 2002, followed by converting the number of days to years. The information of outcome was obtained by the database of Korea Central Cancer Registry, Seoul Regional Cancer Registry, and Korea Statistical Office. The relative risk (RR) and its 95% confidence interval (CI) values of smoking were calculated using Cox proportional hazards regression stratified on potential confounders. During the follow-up periods, 78 cases of lung cancer occurred. The cigarette smoking is the major risk factor and increases the 4.18-fold risk of lung cancer in Korean men. In order to control lung cancer, intervention of quitting smoking is needed.</P>