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      • Quantum dot as probe for disease diagnosis and monitoring

        Mukherjee, Abhishek,Shim, Yumi,Myong Song, Joon WILEY 2016 BIOTECHNOLOGY JOURNAL Vol.11 No.1

        <P><B>Abstract</B></P><P>Semiconductor quantum dots (QD) possess unique optical and electric properties like size‐tunable light emission, narrow emission range, high brightness and photostability. Recent research advances have minimized the toxicity of QDs and they are successfully used in in vitro and in vivo imaging. Encapsulation of QDs into polymeric nanoparticles and linking them with targeting ligands enabled the detection of tumors and cancer cells in vivo. QD‐antibody conjugates were successfully used in monitoring and diagnosis of HIV and myocardial infarction. Application of near infrared (NIR) QDs was found to minimize the absorption and scattering of light by native tissues thus rendering them suitable in deep tissue analysis. Aggregation and endosomal sequestration of QDs pose major challenges for the effective delivery of QDs to the cell cytosol. Toxicity minimization and effective delivery strategies may further increase their suitability for utilization in disease diagnosis. New synthesis of QDs may provide new types of bioconjugates of QDs to biomolecules, which leads to a variety of applications to many challenged research areas. QDs with narrow emission wavelength ranges are very suitable for monitoring multiple cellular targets simultaneously, and still remain the best known probes for imaging as an alternative to traditional fluorophores in disease diagnosis.</P>

      • KCI등재

        Long-chain free fatty acids from Momordica cochinchinensis leaves as attractants to its insect pest, Aulacophora foveicollis Lucas (Coleoptera: Chrysomelidae)

        Abhishek Mukherjee,Nupur Sarkar,Anandamay Barik 한국응용곤충학회 2014 Journal of Asia-Pacific Entomology Vol.17 No.3

        Extraction, thin layer chromatography, and gas chromatography–mass spectrometry of young, mature, andsenescent leaves of Momordica cochinchinensis Spreng revealed 13 free fatty acids, representing a total of82.29, 91.30, and 68.52% of fatty acids in young, mature, and senescent leaves, respectively. Palmitic acid wasthe predominant fatty acid followed by stearic acid in three types of leaves. The free fatty acids from young,mature, and senescent leaves attracted female Aulacophora foveicollis Lucas (Coleoptera: Chrysomelidae) at theminimal concentrations of 4, 2, and 8 μg, respectively; whereas the mixtures of synthetic fatty acids mimickingfree fatty acids of young, mature, and senescent leaves showed attraction at the minimal concentrations of 4, 2,and 10 μg, respectively, in Y-shaped glass tube olfactometer bioassay under laboratory condition. The resultsindicate that A. foveicollismay employ long-chain free fatty acids as an olfactory cue for host location. The individualsynthetic fatty acids mimicking the proportions detected in three types of leaves were also evaluated througholfactometer bioassay. Only synthetic palmitic acid at theminimal amount of 2.17 μg attracted the insect. A syntheticblend of fatty acids mimicking 8 μg free fatty acid concentration of mature leaves or an amount of 5.42 μg palmiticacid produced the highest attraction of the insect. Hence 5.42 μg palmitic acid might be used for insect pestmanagementprogram such as baited traps.

      • SCIESCOPUSKCI등재

        Role of Fermentation in Improving Nutritional Quality of Soybean Meal - A Review

        Mukherjee, Runni,Chakraborty, Runu,Dutta, Abhishek Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.11

        Soybean meal (SBM), a commonly used protein source for animal feed, contains anti-nutritional factors such as trypsin inhibitor, phytate, oligosaccharides among others, which limit its utilization. Microbial fermentation using bacteria or fungi has the capability to improve nutritional value of SBM by altering the native composition. Both submerged and solid state fermentation processes can be used for this purpose. Bacterial and fungal fermentations result in degradation of various anti-nutritional factors, an increase in amount of small-sized peptides and improved content of both essential and non-essential amino acids. However, the resulting fermented products vary in levels of nutritional components as the two species used for fermentation differ in their metabolic activities. Compared to SBM, feeding non-ruminants with fermented SBM has several beneficial effects including increased average daily gain, improved growth performance, better protein digestibility, decreased immunological reactivity and undesirable morphological changes like absence of granulated pinocytotic vacuoles.

      • KCI등재

        Maxillo-facial Extraskeletal Myxoid Chondrosarcoma: A Case Report and Discussion

        Ratnadeep Ganguly,Abhishek Mukherjee 대한병리학회 2011 Journal of Pathology and Translational Medicine Vol.45 No.6

        In this report, we share our experience of a case of maxillo-facial extraskeletal myxoid chondrosarcoma, a very rare location for this neoplasm. In addition, a literature review is provided. The patient, a 61-year-old male, had a maxillary mass encroaching on the nasal cavity. After debulking, the tumor recurred, attaining its presurgical proportion in two months. The patient improved clinically with radiation and remained stable for about one year. However, he ultimately developed metastases in his lung which were treated with palliative chemotherapy with a good outcome lasting three months. We could find only eight reported cases of this tumor in the head region of which two are in the maxilla; hence, ruling out other primary sites is mandatory for a patient presenting with a primary head and neck mass. Surgical removal may be complicated because of the location. A combination of surgery and radiation is the management of choice, with palliative chemotherapy in metastasis.

      • KCI등재

        Ecological analysis of nematodes associated with vegetable-maize cropping system at Dhapa, Kolkata (India)

        Mondal Sandip,Ghosh Sekhar,Mukherjee Abhishek,Rahaman Khan Matiyar 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.4

        The study focused on the ecological analysis of plant and soil nematode communities associated with vegetablesmaize crop sequences in the eastern fringe of Kolkata at Dhapa from December 2011 to April 2014 at a monthly interval. Plant-parasitic nematodes like Pratylenchus zeae, Meloidogyne incognita, Hoplolaimus indicus, Helicotylenchus dihystera, Tylenchorhynchus brevilineatus, Rotylenchulus reniformis, and Criconemoides onoensis were observed in two major cropping sequences of chilli-amaranthus-maize-radish-cauliflower and amaranthus-maize-cabbage-chilli. Among them, R. reniformis was found to be the most prevalent genera with the highest relative prominence value (RPV) of 27.29 followed by P. zeae (20.30) and T. brevilineatus (16.70). The population dynamics of P. zeae revealed the lowest density of the nematode was recorded (26 per 200 cc of soil + 5 g of the root) in March and the highest (634) in September. The variation in the abundances of other PPNs was also noted, and that attributed to the crops in the crop sequence and weather conditions. Low numbers of R. reniformis was found in the maize rhizosphere. The saprozoic nematodes (SNs) maintained higher mean densities (1734/200 cc soil); they were recorded in high numbers in the rainy season as compared to other seasons. No significant differences in the Shannon diversity index (H′), evenness (J) were observed across the growing period. A significant relationship was found between nematode abundance and climatic variables observed. This study provides baseline information on nematodes associated with maize-based cropping system, population abundance, Mylonchulus-SNs relationships, and population fluctuation in response to environmental factors.

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