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Shirazi, Abolfazl,Mirshams, Mehran The Korean Society for Aeronautical and Space Scie 2014 International Journal of Aeronautical and Space Sc Vol.15 No.2
The pyramidal reaction wheel arrangement is one of the configurations that can be used in attitude control simulators for evaluation of attitude control performance in satellites. In this arrangement, the wheels are oriented in a pyramidal configuration with a tilt angle. In this paper, a study of pyramidal reaction wheel arrangement is carried out in order to find the optimum tilt angle that minimizes total power consumption of the system. The attitude control system is analyzed and the pyramidal configuration is implemented in numerical simulation. Optimization is carried out by using an iterative process and the optimum tilt angle that provides minimum system power consumption is obtained. Simulation results show that the system requires the least power by using optimum tilt angle in reaction wheels arrangement.
Abolfazl Shirazi,Mehran Mirshams 한국항공우주학회 2014 International Journal of Aeronautical and Space Sc Vol.15 No.2
The pyramidal reaction wheel arrangement is one of the configurations that can be used in attitude control simulators for evaluation of attitude control performance in satellites. In this arrangement, the wheels are oriented in a pyramidal configuration with a tilt angle. In this paper, a study of pyramidal reaction wheel arrangement is carried out in order to find the optimum tilt angle that minimizes total power consumption of the system. The attitude control system is analyzed and the pyramidal configuration is implemented in numerical simulation. Optimization is carried out by using an iterative process and the optimum tilt angle that provides minimum system power consumption is obtained. Simulation results show that the system requires the least power by using optimum tilt angle in reaction wheels arrangement.
BMI1 and TWIST1 Downregulated mRNA Expression in Basal Cell Carcinoma
Rajabpour, Fatemeh Vand,Raoofian, Reza,Youssefian, Leila,Vahidnezhad, Hassan,Shahshahani, Mostafa Mirshams,Fathi, Hamidreza,Noormohammadpour, Pedram,Hesari, Kambiz Kamyab,Hashemzadeh-Chaleshtori, Mort Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.8
Background: BMI1, TWIST1 and SNAI2/SLUG have been implicated in aggressive behavior of squamous cell carcinoma (SCC) and melanoma and BMI1 expression could identify subtypes of Merkel cell carcinoma (MCC). However, BMI1, TWIST1 and SNAI2 expression levels in basal cell carcinomas (BCCs) have not been elucidated. We hypothesized BCC could be a good model system to decipher mechanisms which inhibit processes that drive tumor metastasis. The aim of this study was to examine the mRNA expression level of BMI1, TWIST1, and SNAI2 in BCCs. Materials and Methods: Thirty-five fresh non-metastatic BCC tissue samples and seven fresh normal skin tissue samples were evaluated by real-time RT-PCR. Results: BMI1 and TWIST1 demonstrated marked down-regulation (p<0.00l, p=0.00l respectively), but SNAI2 showed no significant change (p=0.12). Conclusions: Previous literature has clearly demonstrated a positive association between BMI1 and TWIST1 expression and metastatic BCC, aggressive SCC and melanoma. Here, we demonstrated a negative association between BMI1 and TWIST1 mRNA expression level and BCC.
Mahdi N. Mahyari,Hasan Karimi,Hasan Naseh,Mehran Mirshams 대한기계학회 2010 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.24 No.10
The focus of the present study is to investigate the effectiveness of installing vortex breakers at the outlet of launch vehicle tanks on postponing vortex formation and decreasing the critical height of propellants while discharging. Analytical results in the absence of a vortex breaker show that the effects of the Weber and Reynolds numbers in the flow field can be ignored for values greater than 720 and 1.1 × 105, respectively; and critical height can be considered as a function of Froude number under aforementioned conditions. The analytical criteria are verified by two-dimensional, axis symmetrical, transient and two-phase numerical model. Eventually, some experiments are conducted to examine the effectiveness of the applied vortex breakers in reduction of the critical height of propellant. Experimental results show that a 30% decrease can be achieved in critical height by using a particular type of vortex breaker. Additionally, the carried out simulations for an existing two-stage launch vehicle indicate a 13% increase in orbital altitude, which in turn proves the considerable improvement in launch vehicle mass/energetic capabilities.