Adaptive Call Admission and Bandwidth Control in DVB-RCS Systems

Marchese, Mario,Mongelli, Maurizio The Korea Institute of Information and Commucation 2010 Journal of communications and networks Vol.12 No.6

The paper presents a control architecture aimed at implementing bandwidth optimization combined with call admission control (CAC) over a digital video broadcasting (DVB) return channel satellite terminal (RCST) under quality of service (QoS) constraints. The approach can be applied in all cases where traffic flows, coming from a terrestrial portion of the network, are merged together within a single DVB flow, which is then forwarded over the satellite channel. The paper introduces the architecture of data and control plane of the RCST at layer 2. The data plane is composed of a set of traffic buffers served with a given bandwidth. The control plane proposed in this paper includes a layer 2 resource manager (L2RM), which is structured into decision makers (DM), one for each traffic buffer of the data plane. Each DM contains a virtual queue, which exactly duplicates the corresponding traffic buffer and performs the actions to compute the minimum bandwidth need to assure the QoS constraints. After computing the minimum bandwidth through a given algorithm (in this view the paper reports some schemes taken in the literature which may be applied), each DM communicates this bandwidth value to the L2RM, which allocates bandwidth to traffic buffers at the data plane. Real bandwidth allocations are driven by the information provided by the DMs. Bandwidth control is linked to a CAC scheme, which uses current bandwidth allocations and peak bandwidth of the call entering the network to decide admission. The performance evaluation is dedicated to show the efficiency of the proposed combined bandwidth allocation and CAC.

Adaptive Call Admission and Bandwidth Control in DVB-RCS Systems

Mario Marchese,Maurizio Mongelli 한국통신학회 2010 Journal of communications and networks Vol.12 No.6

The paper presents a control architecture aimed at implementing bandwidth optimization combined with call admission control (CAC) over a digital video broadcasting (DVB) return channel satellite terminal (RCST) under quality of service (QoS)constraints. The approach can be applied in all cases where traffic flows, coming from a terrestrial portion of the network, are merged together within a single DVB flow, which is then forwarded over the satellite channel. The paper introduces the architecture of data and control plane of the RCST at layer 2. The data plane is composed of a set of traffic buffers served with a given bandwidth. The control plane proposed in this paper includes a layer 2resource manager (L2RM), which is structured into decision makers (DM), one for each traffic buffer of the data plane. Each DM contains a virtual queue, which exactly duplicates the corresponding traffic buffer and performs the actions to compute the minimum bandwidth need to assure the QoS constraints. After computing the minimum bandwidth through a given algorithm (in this view the paper reports some schemes taken in the literature which may be applied), each DM communicates this bandwidth value to the L2RM, which allocates bandwidth to traffic buffers at the data plane. Real bandwidth allocations are driven by the information provided by the DMs. Bandwidth control is linked to a CAC scheme, which uses current bandwidth allocations and peak bandwidth of the call entering the network to decide admission. The performance evaluation is dedicated to show the efficiency of the proposed combined bandwidth allocation and CAC.

Is percutaneous destruction of a solitary liver colorectal metastasis as effective as a resection?

Ugo Marchese,Heloise Seux,Jonathan Garnier,Jacques Ewald,Gilles Piana,Bernard Lelong,Cecile De Chaisemartin,Helene Meillat,Jean-Robert Delpero,Olivier Turrini 한국간담췌외과학회 2021 Annals of hepato-biliary-pancreatic surgery Vol.25 No.2

Backgrounds/Aims: Surgical resection remains the gold standard in the treatment of colorectal liver metastasis. However, when a patient presents with a deep solitary colorectal liver metastasis (S-CLM), the balance between the hepatic volume sacrificed and the S-CLM volume is sometimes clearly unappropriated. Thus, alternatives to surgery, such as operative and percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA), have been developed. This study aimed to identify the prognostic factors affecting survival of patients with S-CLM who undergo curative-intent liver resection or local destruction (RFA or MWA). Methods: We retrospectively identified 211 patients with synchronous or metachronous S-CLM who underwent either surgical resection (n=182) or local destruction (RFA or MWA; n=29) according to the S-CLM size, location, and surrounding Glissonian structures. Results: Patients who underwent RFA or MWA had S-CLM of a smaller size than those who underwent resection (mean 19.7 vs. 37.3 mm, p<.01). The 1-, 3-, and 5-year overall survival (OS) rates were 97.4%, 84.9%, and 74.9%, respectively. The 1-, 3-, and 5-year disease-free survival (DFS) rates were 77.9%, 47%, and 38.9%, respectively. S-CLM located in the left liver (p=.04), S-CLM KRAS mutation (p<.01), and extra-hepatic recurrence (p<.01) were identified as independent poor risk factors for overall survival (OS); the OS and DFS were comparable in patients with surgical procedure or percutaneous MWA. Conclusions: In eligible S-CLM cases, percutaneous MWA seems to be as oncologically efficient as surgical resection and should be include in the decision-tree for treatment strategies.

A Measurement-Based Adaptive Control Mechanism for Pricing in Telecommunication Networks

Davoli, Franco,Marchese, Mario,Mongelli, Maurizio The Korea Institute of Information and Commucation 2010 Journal of communications and networks Vol.12 No.3

The problem of pricing for a telecommunication network is investigated with respect to the users' sensitivity to the pricing structure. A functional optimization problem is formulated, in order to compute price reallocations as functions of data collected in real time during the network evolution. No a-priori knowledge about the users' utility functions and the traffic demands is required, since adaptive reactions to the network conditions are sought in real time. To this aim, a neural approximation technique is studied to exploit an optimal pricing control law, able to counteract traffic changes with a small on-line computational effort. Owing to the generality of the mathematical framework under investigation, our control methodology can be generalized for other decision variables and cost functionals.

DO DIRTY INDUSTRIES CONDUCT OFFSHORE ASSEMBLY IN DEVELOPING COUNTRIES ?

Clark, Don P .,Marchese, Serafino,Zarrilli, Simonetta 한국국제경제학회 2000 International Economic Journal Vol.14 No.3

A Measurement-Based Adaptive Control Mechanism for Pricing in Telecommunication Networks

Franco Davoli,Mario Marchese,Maurizio Mongelli 한국통신학회 2010 Journal of communications and networks Vol.12 No.3

The problem of pricing for a telecommunication network is investigated with respect to the users’ sensitivity to the pricing structure. A functional optimization problem is formulated,in order to compute price reallocations as functions of data collected in real time during the network evolution. No a-priori knowledge about the users’ utility functions and the traffic demands is required, since adaptive reactions to the network conditions are sought in real time. To this aim, a neural approximation technique is studied to exploit an optimal pricing control law, able to counteract traffic changes with a small on-line computational effort. Owing to the generality of the mathematical framework under investigation,our control methodology can be generalized for other decision variables and cost functionals.

Prognostic value of ultra-low-pass whole-genome sequencing of circulating tumor DNA in hepatocellular carcinoma under systemic treatment

Miguel Sogbe,Idoia Bilbao,Francesco P. Marchese,Jon Zazpe,Annarosaria De Vito,Marta Pozuelo,Delia D’Avola,Mercedes Iñarrairaegui,Carmen Berasain,Maria Arechederra,Josepmaria Argemi,Bruno Sangro 대한간학회 2024 Clinical and Molecular Hepatology(대한간학회지) Vol.30 No.2

Background/Aims: New prognostic markers are needed to identify patients with hepatocellular carcinoma (HCC) who carry a worse prognosis. Ultra-low-pass whole-genome sequencing (ULP-WGS) (≤0.5× coverage) of cell-free DNA (cfDNA) has emerged as a low-cost promising tool to assess both circulating tumor DNA (ctDNA) fraction and large structural genomic alterations. Here, we studied the performance of ULP-WGS of plasma cfDNA to infer prognosis in patients with HCC. Methods: Plasma samples were obtained from patients with HCC prior to surgery, locoregional or systemic therapy, and were analyzed by ULP-WGS of cfDNA to an average genome-wide fold coverage of 0.3x. ctDNA and copy number alterations (CNA) were estimated using the software package ichorCNA. Results: Samples were obtained from 73 HCC patients at different BCLC stages (BCLC 0/A: n=37, 50.7%; BCLC B/C: n=36, 49.3%). ctDNA was detected in 18 out of 31 patients who received systemic treatment. Patients with detectable ctDNA showed significantly worse overall survival (median, 13.96 months vs not reached). ctDNA remained an independent predictor of prognosis after adjustment by clinical-pathologic features and type of systemic treatment (hazard ratio 7.69; 95%, CI 2.09–28.27). Among ctDNA-positive patients under systemic treatments, the loss of large genomic regions in 5q and 16q arms was associated with worse prognosis after multivariate analysis. Conclusions: ULP-WGS of cfDNA provides clinically relevant information about the tumor biology. The presence of ctDNA and the loss of 5q and 16q arms in ctDNA-positive patients are independent predictors of worse prognosis in patients with advanced HCC receiving systemic therapy.

Small Ubiquitin-like Modifier Modification of Arrestin-3 Regulates Receptor Trafficking

Wyatt, D.,Malik, R.,Vesecky, A.C.,Marchese, A. The American Society for Biochemistry and Molecula 2011 The Journal of biological chemistry Vol.286 No.5

Productivity Enhancement in Directed Energy Deposition: The Oscillating Scanning Strategy Approach

Alberta Aversa,Alessandro Carrozza,Giulio Marchese,Stefano Felicioni,Michele De Chirico,Mariangela Lombardi,Federica Bondioli,Paolo Fino 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.7

Directed Energy Deposition (DED) is an additive manufacturing process that enables the production of large metal componentsby melting the feedstock material while being deposited. An improvement of the production speed of this processwould further increase its applicability in many industrial fields. The DED building rate is strictly related to the buildingparameters adopted, in particular to the laser spot diameter, which also affects the build accuracy and the surface quality ofthe components. The possibility of using a variable laser spot would result in a significant increase in the production rate inbulky zones, while also providing a good surface quality where needed. In the present work, an oscillating scanning strategywas used to create a large apparent laser spot (+ 170% of the nominal value) to produce 316L stainless steel samples via DED. The optimisation of the DED parameters with the oscillating strategy was performed using the single scan tracks (SSTs)approach. The morphologies of the SSTs obtained with different process parameters were assessed and the geometrical featuresrelated to the melt pools were analysed in order to select the most suitable X and Z displacements for the production ofthe cubic samples. The analyses of the cubes revealed that, if the correct overlap among nearby scans is selected, it is possibleto obtain dense samples with all the oscillating diameters tested. Finally, comparing the building rate and powder efficiencyvalues confirmed that this method can accelerate the building process and improve its overall performance.

Recovery from minimally invasive vs. open surgery in kidney cancer patients: Opioid use and workplace absenteeism

Marieke J. Krimphove,Stephen W. Reese,Xi Chen,Maya Marchese,Daniel Pucheril,Eugene Cone,Wesley Chou,Karl H. Tully,Adam S. Kibel,Richard D. Urman,Steven L. Chang,Luis A. Kluth,Prokar Dasgupta,Quoc-Dien 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.1

Purpose: Does surgical approach (minimally invasive vs. open) and type (radical vs. partial nephrectomy) affects opioid use and workplace absenteeism. Materials and Methods: Retrospective multivariable regression analysis of 2,646 opioid-naïve patients between 18 and 64 undergoing radical or partial nephrectomy via either a minimally invasive vs. open approach for kidney cancer in the United States between 2012 and 2017 drawn from the IBM Watson Health Database was performed. Outcomes included: (1) opioid use in opioid-naïve patients as measured by opioid prescriptions in the post-operative setting at early, intermediate and prolonged time periods and (2) workplace absenteeism after surgery. Results: Patients undergoing minimally invasive surgery had a lower odds of opioid use in the early and intermediate post-operative periods (early: odds ratio [OR], 0.77; 95% confidence interval [CI], 0.62–0.97; p=0.02, intermediate: OR, 0.60; 95% CI, 0.48–0.75; p<0.01), but not in the prolonged setting (prolonged: OR, 1.00; 95% CI, 0.75–1.34; p=0.98) and had earlier return to work (minimally invasive vs. open: −10.53 days; 95% CI, −17.79 to −3.26; p<0.01). Controlling for approach, patient undergoing partial nephrectomy had lower rates of opioid use across all time periods examined and returned to work earlier than patients undergoing radical nephrectomy (partial vs. radical: −14.41 days; 95% CI, −21.22 to −7.60; p<0.01). Conclusions: Patients undergoing various forms of surgery for kidney cancer had lower rates of peri-operative opioid use, fewer days of workplace absenteeism, but no difference in long-term rates of opioid use in patients undergoing minimally invasive as compared to open surgery.