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Unusual Uptake of Prostate Specific Tracer <sup>68</sup>Ga-PSMA-HBED-CC in a Benign Thyroid Nodule
Damle, Nishikant Avinash,Tripathi, Madhavi,Chakraborty, Partha Sarathi,Sahoo, Manas Kumar,Bal, Chandrasekhar,Aggarwal, Shipra,Arora, Geetanjali,Kumar, Praveen,Kumar, Rajeev,Gupta, Ravikant The Korea Society of Nuclear Medicine 2016 핵의학 분자영상 Vol.50 No.4
$^{68}Ga$-Prostate specific membrane antigen- N,N′-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N′-diacetic acid- positron emission tomography/computed tomography or 68 Ga- HBED-CC-PSMA PET/CT, popularly known as PSMA PET/CT, is able to detect a small volume of recurrent prostate carcinoma (PC) when there is a prostate specific antigen (PSA) rise on follow-up after prostatectomy or other definitive treatment for PC. The use of PSMA PET/CT in the initial staging in PC is uncertain at this time. Clinical studies are underway to define its exact role in the management of the disease. At the same time it is important to be aware of unexpected sites of uptake of this ligand. We present here the case of a 62-year-old male patient who underwent prostatectomy for adenocarcinoma prostate. He also had a long-standing left solitary thyroid nodule (STN). Four months after surgery, he had a rising trend in serum PSA levels on three occasions, but the absolute value was less than 4 at all times. He underwent a $^{68}Ga$-PSMA-HBED-CC PET/CT, but it did not reveal any recurrent/metastatic site of disease. However, there was increased tracer uptake in the left STN. Fine needle aspiration cytology revealed features of atypia of undetermined significance, Bethesda category III. The patient underwent a left hemithyroidectomy and the histopathology showed features of a follicular adenoma.
Infected Lower Limb Megaprosthesis on 68Ga-NOTA-Ubiquicidin PET/CT Imaging
Prateek Kaushik,Satya Dev Maurya,Nishikant Damle,Sanjana Ballal,Venkatesan Sampath Kumar,Chandrasekhar Bal,Madhavi Tripathi 대한핵의학회 2022 핵의학 분자영상 Vol.56 No.3
Pain after prosthesis implant is a common clinical problem which requires distinction of septic from aseptic causes since the treatment differs. Non-invasive imaging methods play an important role in the diagnosis. Radiolabelled ubiquicidin can be used for imaging infection by binding directly to bacterial cell wall. We describe a case of a 24-year-old man with right lower limb megaprosthesis which did not show any loosening on computed tomography (CT) but was accurately diagnosed as infected prosthesis with 68Ga-NOTA-ubiquicidin(29-41) acetate scan.
Arora, Saurabh,Damle, Nishikant Avinash,Passah, Averilicia,Yadav, Madhav Prasad,Ballal, Sanjana,Aggarwal, Vivek,Gupta, Yashdeep,Kumar, Praveen,Tripathi, Madhavi,Bal, Chandrasekhar 대한핵의학회 2018 핵의학 분자영상 Vol.52 No.3
Multiple endocrine neoplasia type 1 (MEN1) syndrome is characterized by combined occurrence of tumors of endocrine glands including the parathyroid, the pancreatic islet cells, and the anterior pituitary gland. Parathyroid involvement is the most common manifestation and usually the first clinical involvement in MEN1 syndrome, followed by gastroentero-pancreatic neuroendocrine tumors (NETs). Here we present a case where the patient initially presented with metastatic gastric NET and a single parathyroid adenoma was detected incidentally on $^{68}Ga$-DOTANOC PET/CT done as part of post $^{177}Lu$-DOTATATE therapy (PRRT) follow-up. Further $^{18}F$-fluorocholine PET/CT showed four adenomas for which the patient subsequently underwent subtotal parathyroidectomy.