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      • KCI등재

        A review of experimental methods for characterising composite viscosities of continuous fibre-reinforced polymer composites

        Wang Jinhuo,Han Yang,Ge Xiaohong,Qi Zhengbing,Zhao Jun,Wang Rongwen,Wu Huawei,Han Taiping,Sun Shaoxun,Wang Hui,Lin Jia,Liu Yuejun,Kong Xiangsong,Chen Qiming,Zeng Xiangxu 한국유변학회 2023 Korea-Australia rheology journal Vol.35 No.2

        Optimisation design of composite structures requires an accurate predictive model for forming behaviour. The simulation process contains a number of model parameters which include transverse and longitudinal viscosities of continuous fibrereinforced viscous composites, fundamental to predicting the shear rheology. Shearing the unidirectional composite along the fibre direction gives a measure of the longitudinal viscosity (LV), whilst shearing across or transverse to the fibre direction gives a measure of the transverse viscosity (TV). Numerous experimental work was conducted in the past to measure these two viscosities for various materials. However, conflicting measurements by different test methods were obtained and these apparent discrepancies had not yet been systematically investigated in any single study. This paper reviews previous work on characterisation techniques to further understand the cause of such discrepancy, and hence to improve measurement accuracy, which would benefit future work on theoretical modelling of the composite viscosities and optimisation simulation of composites forming. Some important findings, such as effects of resin-rich areas, contributory factors of elastic effects, non-Newtonian behaviour for composites with Newtonian matrix, aspect ratio and end effects of test samples, geometry effects of fibres and fibre rearrangement during shearing, existence of a mathematical relationship between LV and TV and necessary benchmarking exercise using Newtonian matrix composites, were summarised.

      • Systematic Review on Epstein-Barr Virus (EBV) DNA in Diagnosis of Nasopharyngeal Carcinoma in Asian Populations

        Han, Bao-Lin,Xu, Xiang-Ying,Zhang, Chun-Zhi,Wu, Jian-Juan,Han, Chun-Feng,Wang, Hui,Wang, Xuan,Wang, Guang-Shun,Yang, Shu-Juan,Xie, Yao Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

        Objective: To conduct a meta-analysis to investigate the value of EBV DNA in diagnosis of nasopharyngeal cancer (NPC) in Asian populations, and provide important evidence for screening. Methods: Prospective or respective case-control or cohort studies regarding the detection role of EBV DNA for NPC were included in our study. We conducted a comprehensive literature search in PubMed, EMBASE, and the Chinese Biomedical Database (CBM database between January 1980 and March 2012. Results: A total of 18 studies with 1492 NPC cases and 2641 health controls were included. Almost of the included studies were conducted in China, and only one other conducted in Thailand. The overall results demonstrated that the pooled sensitivity, specificity, positive likelihood (+LR) and negative likelihood (-LR) were 0.73 (0.71-0.75), 0.89 (0.88-0.90), 8.84 (5.65-13.84) and 0.19(0.11-0.32), respectively. The overall EBV DNA detection showed the largest area of 0.932 under the summary receiver operator curve (SROC). The accuracy of detection by plasma for NPC (0.86) was higher than in serum (0.81), with largest areas under the SROC of 0.97 and 0.91, respectively. Conclusion: Our results demonstrated the EBV DNA detection in plasma or serum has high sensitivity and specificity in diagnosis of NPC, especially in Chinese populations with a high risk of cancer.

      • Scheduling with machine-learning-based flow detection for packet-switched optical data center networks

        Wang, Lin,Wang, Xinbo,Tornatore, Massimo,Kim, Kwang Joon,Kim, Sun Me,Kim, Dae-Ub,Han, Kyeong-Eun,Mukherjee, Biswanath IEEE 2018 Journal of optical communications and networking Vol.10 No.4

        <P>A scalable, low-latency, high-speed, and energy- efficient data center network is a key element in the deployment of future large-scale data centers, and photonic switching has recently been recognized as a promising solution to fulfill these goals. In this study, we present a packet-switched optical network (PSON) architecture with centralized control for intra-data-center connectivity. For efficient PSON operation, intelligent yet low-complexity bandwidth-scheduling algorithms are critical. To align with realistic traffic flows in a data center, we consider “mice flow,” which occurs frequently but carries a small number of bytes, and “elephant flow,” which occurs occasionally but has a huge number of bytes. To classify traffic flows with different characteristics, we investigate various machine-learning (classification) techniques, such as C4.5 and Naïve Bayes Discretization, and compare their performance in terms of accuracy and classification speed. We also develop a priority-aware scheduling algorithm for packet switching, which is optimized for PSON, and is adaptive to flow classification under a dynamic traffic scenario. Numerical simulations show that our proposed scheduling algorithm assisted by flow-classification techniques can outperform a benchmark algorithm in terms of average delay and packet-loss ratio.</P>

      • Dynamic bandwidth and wavelength allocation scheme for next-generation wavelength-agile EPON

        Lin Wang,Xinbo Wang,Tornatore, Massimo,Hwan Seok Chung,Han Hyub Lee,Soomyung Park,Mukherjee, Biswanath IEEE 2017 Journal of optical communications and networking Vol.9 No.3

        <P>Recently, the IEEE 802.3 Ethernet Working Group has classified three architectures for the nextgeneration Ethernet passive optical network (NG-EPON). They are called single-scheduling domain (SSD) PON, multi-scheduling domain (MSD) PON, and wavelength-agile (WA) PON, and they differ based on how a group of optical network units (ONUs) share awavelength. Existing dynamic bandwidth and wavelength allocation (DBWA) schemes for conventional EPON can be applied to MSD-PON and SSDPON, but not WA-PON. This is because WA-PON is a new architecture with full flexibility where a flexible number of wavelengths can be assigned to one ONU, and multiple ONUs can transmit at the same time. In this work, we develop a mathematical model and a novel DBWA scheme for transmission scheduling in WA-PON. However, as WA-PON incurs penalties in terms of delay and power consumption when an ONU activates its transmissions on new wavelengths, a trade-off between energy saving and data-transfer latency reduction needs to be carefully addressed when performing transmission scheduling. So, we develop a power-consumption model and modify the proposed DBWA scheme to enhance the energy efficiency ofWA-PON. Finally, we conduct simulation experiments for performance evaluation of the three PON architectures in terms of latency and packet loss ratio.We quantitatively investigate the influence of various parameters, such as the number of ONU transceivers and ONU buffer size, onWA-PON latency and packet loss ratio, and we evaluate the energy efficiency gain of the modified DBWA scheme.</P>

      • KCI등재

        Analysis of dynamical stability of rigid-flexible hybrid-driven lower limb rehabilitation robot

        Yan-lin Wang,Ke-yi Wang,Zi-xing Zhang,Zhuang Han,Wan-li Wang 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.4

        The research of the safety problem of the cable-driven lower limb rehabilitation robots (CDLR) is not considered in the related report. Hence, the purpose of this paper is to study the dynamical stability evaluation method of a rigid-flexible hybrid-driven lower limb rehabilitation robot system (RFHDLR) to meet the training requirements of different patients in different rehabilitation stages. In order to improve the flexibility and operational performance of the robot system, one rigid motion chain is introduced into the cable-driven parallel robot (CDPR) to form a RFHDLR. Secondly, the motion planning strategy of the rigid motion chain is analyzed. Then, based on the kinematics and dynamics of the robot system, the cable tension performance factor and the system stiffness performance factor of the robot system are defined, and the static stability evaluation method and index of RFHDLR are obtained by the weighting method. Considering the patient's ability to withstand the motion velocity and the effect of the volatility of slide motion velocity of the rigid motion chain on the safety of the robot system, the velocity performance factor of the robot system is proposed. The dynamical stability evaluation method and index of RFHDLR are discussed based on the static stability evaluation method and the velocity influence function. Finally, for the two planning strategies of the rigid motion chain, the experimental study of the planned training trajectory of the lower limb traction point is performed based on simulation analysis. The experimental results verify the correctness of the stability evaluation method and provide a reference for further studying the training task planning and the control strategy.

      • KCI등재

        Appraise and analysis of dynamical stability of cable-driven lower limb rehabilitation training robot

        Yan-lin Wang,Ke-yi Wang,Wan-li Wang,Peng-cheng Yin,Zhuang Han 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.11

        This paper presents a problem that traditional methods cannot evaluate the dynamical stability of the under-constraint cable-driven lower limb rehabilitation training robot (CLLRTR). An analytical method is presented to evaluate the dynamical stability of CLLRTR. Firstly, position performance factor, posture performance factor and cable tension performance factor are defined based on the kinematics and dynamics of CLLRTR. An appraisal index and method of the dynamical stability for CLLRTR with the hybrid force-position-pose approach is proposed by using the weighted average method among three performance factors. Secondly, the stable workspace and robustness workspace with the external forces are defined according to the stability margin. Finally, the simulation analysis and the experimental study are used to illustrate the distribution of the dynamical stability in the whole workspace of CLLRTR. The results show that the experimental results are the same as the theoretical simulation analysis results. So the appraisal index of the dynamical stability can be used to evaluate the dynamical stability of CLLRTR. It will provide a foundation for the trajectory planning and control strategy of CLLRTR training pattern.

      • KCI등재

        Aluminum Oxide/Fluoride Self-Assembled Monolayer Double Gate Dielectric for Solution-Processed Indium Oxide Thin-Film Transistors

        Xiao-Lin Wang,Shan Fei,Zhao Han-Lin,Lee Jae-Yun,Yoo Suchang,Ryu Heung Gyoon,Choi Seungkeun,Anvar Tukhtaev,Kim Sung-Jin 대한금속·재료학회 2022 ELECTRONIC MATERIALS LETTERS Vol.18 No.5

        A high-performance indium oxide (In 2 O 3 )-based thin-film transistor (TFT) was prepared with aluminum oxide/fluorinated self-assembled monolayer (Al 2 O 3 /F-SAM) double-gate dielectric layer. The Al 2 O 3 /F-SAM double gate dielectric layer improved the performance of the In 2 O 3 -based TFT by reducing the device leakage current. In addition, devices with a double-gate dielectric layer show improved stability under negative bias stress testing compared to devices with a single gate dielectric layer (Al 2 O 3 ), shifting a threshold voltage by only 0.4 V. These results suggest that the Al 2 O 3 /F-SAM doublelayer gate dielectric layer can enhance the performance of In 2 O 3 -based TFTs. Furthermore, it can be used to improve the performance of other metal oxide-based devices by minimizing the leakage current at low operating voltages at low cost.

      • Diagnostic Performance of HPV E6/E7 mRNA and HPV DNA Assays for the Detection and Screening of Oncogenic Human Papillomavirus Infection among Woman with Cervical Lesions in China

        Wang, Hye-young,Lee, Dongsup,Park, Sunyoung,Kim, Geehyuk,Kim, Sunghyun,Han, Lin,Yubo, Ren,Li, Yingxue,Park, Kwang Hwa,Lee, Hyeyoung Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17

        Background: Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and it is responsible for most cases of cervical uterine cancer. Although HPV infections of the cervix do not always progress to cancer, 90% of cervical cancer cases have been found to be associated with high risk HPV (HR-HPV) infection. HPV DNA testing is widely used, along with Papanicolaou (Pap) testing, to screen for cervical abnormalities. However, there are no data on the prevalence of genotype-specific HPV infections assessed by measuring HPV E6/E7 mRNA in women representative of the Chinese population across a broad age range. Materials and Methods: In the present study, we compared the results with the CervicGen HPV RT-qDx assay, which detects 16 HR-HPV genotypes (Alpha-9: HPV 16, 31, 33, 35, 52, and 58; Alpha-7: HPV 18, 39, 45, 51, 59, and 68; and Alpha-5, 6: HPV 53, 56, 66, and 69), and the REBA HPV-ID assay, which detects 32 HPV genotypes based on the reverse blot hybridization assay (REBA) for the detection of oncogenic HPV infection according to cytological diagnosis. We also investigated the prevalence and genotype distribution of HPV infection with a total of 324 liquid-based cytology samples collected in western Shandong province, East China. Results: The overall HPV prevalences determined by HPV DNA and HPV E6/E7 mRNA assays in this study were 79.9% (259/324) and 55.6% (180/324), respectively. Although the positivity of HPV E6/E7 mRNA expression was significantly lower than HPV DNA positivity, the HPV E6/E7 mRNA assay showed greater specificity than the HPV DNA assay (88.6% vs. 48.1%) in normal cytology samples. The prevalence of Alpha-9 (HPV 16, 31, 33, 35, 52, and 58) HPV infection among these women accounted for up to 80.3% and 76.1% of the high-grade lesions detected in the HPV mRNA and DNA tests, respectively. The HR-HPV genotype distribution, based on HPV DNA and E6/E7 mRNA expression by age group in patients with cytologically confirmed lesions, was highest in women aged 40 to 49 years (35.9% for cytologically confirmed cases, Pearson correlation r value=0.993, p<0.001) for high-grade lesions. Among the oncogenic HR-HPV genotypes for all age groups, there was little difference in the distribution of HPV genotypes between the HPV DNA (HPV -16, 53, 18, 58, and 33) and HPV E6/E7 mRNA (HPV -16, 53, 33, 58, and 18) assays. HPV 16 was the most common HPV genotype among women with high-grade lesions. Conclusions: Our results suggest that the HPV E6/E7 mRNA assay can be a sensitive and specific tool for the screening and investigation of cervical cancer. Furthermore, it may provide useful information regarding the necessity for early cervical cancer screenings and the development of additional effective HPV vaccines, such as one for HPV 53 and 58. Additionally, gaining knowledge of HPV distribution may also inform us about ecological changes in HPV after the vaccination.

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