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Lee, Taeksu,Wi, Jung-Sub,Oh, Aram,Na, Hee-Kyung,Lee, JaeJong,Lee, Kwangyeol,Lee, Tae Geol,Haam, Seungjoo The Royal Society of Chemistry 2018 Nanoscale Vol.10 No.8
<P>Highly sensitive and reproducible surface enhanced Raman spectroscopy (SERS) requires not only a nanometer-level structural control, but also superb uniformity across the SERS substrate for practical imaging and sensing applications. However, in the past, increased reproducibility of the SERS signal was incompatible with increased SERS sensitivity. This work presents multiple silver nanocrystals inside periodically arrayed gold nanobowls (SGBs) <I>via</I> an electrochemical reaction at an overpotential of −3.0 V (<I>vs.</I> Ag/AgCl). The gaps between the silver nanocrystals serve as hot spots for SERS enhancement, and the evenly distributed gold nanobowls lead to a high device-to-device signal uniformity. The SGBs on the large sample surface exhibit an excellent SERS enhancement factor of up to 4.80 × 10<SUP>9</SUP>, with excellent signal uniformity (RSD < 8.0 ± 2.5%). Furthermore, the SGBs can detect specific microRNA (miR-34a), which plays a widely acknowledged role as biomarkers in diagnosis and treatment of diseases. Although the small size and low abundance of miR-34a in total RNA samples hinder their detection, by utilizing the advantages of SGBs in SERS sensing, reliable and direct detection of human gastric cancer cells has been successfully accomplished.</P>
Catalytic nanoparticles being facet-controlled
Lee, Kwangyeol,Kim, Minsik,Kim, Heonjo Royal Society of Chemistry 2010 Journal of materials chemistry Vol.20 No.19
<P>The catalytic properties of nanoparticles are determined by the nature of nanoparticle surface. Thus facet-controlled synthesis of catalytic nanoparticles is of paramount importance for both reactive and selective catalysis, and recently various successful synthetic methodologies have been developed to give a number of facet-controlled nanoparticles. In this review, we highlight these recent developments in facet-controlled nanoparticle synthesis along with novel strategies to enhance nanoparticle stability and reactivity.</P> <P>Graphic Abstract</P><P>We highlight the recent developments in facet-controlled nanoparticle-synthesis along with novel strategies to enhance nanoparticle stability and reactivity. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b921857b'> </P>
( Suhyup Lee ),( Abdolreza Hosseindoust ),( Yohan Choi ),( Minju Kim ),( Kwangyeol Kim ),( Junhyung Lee ),( Younghwa Kim ),( Byungjo Chae ) 한국축산학회 2019 한국축산학회지 Vol.61 No.5
The objective of this study was to verify the best mating age of gilts at the first parity. Gilts (n = 86) were divided into nine groups in a factorial arrangement with three Ages (AG1, ≤ 220 d; AG2, 220 to 240 d; AG3, 240 ≤ d), and three weights (WT1 ≤ 140 kg; WT2, 140 to 149 kg; WT3, 150 ≤ kg). A higher body weight gain in AG2 sows during gestation. Sows in AG2 group showed a higher body weight gain at first parity and backfat gain in the parity 2 and 3 during gestation. A greater insulin-like growth factor-1 (IGF-1) was observed in AG1 sows compared with AG3 sows at weaning in the second parity. Sows in WT1 group showed a significant positive effect on the plasma IGF-1 at breeding and weaning time in parity 2. Sows in AG3 group showed a higher plasma leptin at breeding, farrowing, and weaning in the parity 1, and at farrowing in parity 2. Sows in WT3 group showed a higher plasma leptin at breeding, farrowing, and weaning in the parities 1 and 2. Considering the insignificant longevity results, the most efficient time for gilts insemination can be at 220 d when their body weight is 140 kg or lower
모델 기반 차량 전장 시스템 개발 프로세스에 관한 연구
이광열(Kwangyeol Lee),홍성준(Soungjoon Hong),오승호(Sungho Oh),이우택(Wootaik Lee) 한국자동차공학회 2006 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-
Model Based Development Process (MBDP) is popular between automotive electronic industries and automotive company recently. Customer demands have increased and convenience function is more and more complicated in the automotive body system. Model Based Development Process has a merit which can reduce a development period and enhance the reusability of software. This paper describes the DPI Model Based Development Process (DPI-MBDP). It is intended to give a DPI process of developing ECU and system software. Model-based development, in which a simulation model (e.g., Statemate model) is used to finalize software specifications, is used during specification design (prototyping) prior to verification. Rather than immediately verifying the prototype software on actual equipment, an environment (model) is first created in which the actual control of an ECUs can be simulated and verification of the virtual operation performed. In this way, logical mistakes in the specifications, mistakes in micro controller control register configuration and other design errors can be detected in advance, without having to use actual equipment. Moreover, since exception-handling routines can be verified in advance, the burden faced during verification of actual equipment can be reduced and software development performed more efficiently. This process and methodology is applied to a development of a driver memory seat controller as an example.
( Junhyung Lee ),( Abdolreza Hosseindoust ),( Minju Kim ),( Kwangyeol Kim ),( Yohan Choi ),( Joseph Moturi ),( Changhyun Song ),( Songyi Lee ),( Hyunjong Cho ),( Byungjo Chae ) 한국축산학회 2019 한국축산학회지 Vol.61 No.4
This study was conducted to investigate the effects of hot melt extrusion (HME) nano-iron as an alternative for the common ferrous sulfate on iron (Fe) bioavailability, growth performance, nutrient digestibility, intestinal morphology, and intestinal microbiota of weanling pigs. A total of 200 piglets (Landrace × Yorkshire × Duroc) were randomly allotted to seven treatments on the basis of initial body weight (BW) and sex. Treatments were the INO100 (100 ppm Fe as FeSO<sub>4</sub>), HME-Fe levels (50, 75, and 100 ppm nano-Fe as FeSO<sub>4</sub>). ORG100 (100 ppm Fe as iron methionine). In phase 1, the HME50 pigs showed the lowest Fe content in feed and feces. Plasma Fe concentration was increased in HME100 and ORG100 pigs. In phase 2, there were significantly lower concentration of Fe in feed and feces of HME50 pigs (p < 0.01). A lower Fe concentration in the plasma and liver were observed in HME50 pigs compared with HME100 pigs. Concentration of red blood cell (RBC) was the lowest (p < 0.01) for HME50 pigs. During phase 2, the HME100, HME75, and ORG100 pigs showed a higher RBC and hemoglobin values compared with HME50 pigs. Digestibility of gross energy (GE) and crude protein (CP) were significantly higher in HME100 pigs compared with HME50 pigs. There was an increased (p < 0.01) villus height in the duodenum and jejunum of HME100 pigs compared with HME50 pigs. It is concluded that dietary Fe does not improve growth performance of weanling pigs; however, increasing the dietary iron concentration in weanling piglets increased the RBC and hemoglobin. In addition, the potential ability of HME to be used at a lower level (HME75) was observed.