Aflatoxin B₁,메주및 고추기름에 의한 Wistar쥐의 胃癌發生에 관한 硏究

朴貴善 東亞大學校附設基礎科學硏究所 1984 基礎科學硏究論文集 Vol.1 No.1

Rate를 대상으로 Aflatoxin B₁,메주,고추기름을 투여하여 다음과 같은 실험 성적을 얻었다. 1.실험동물의 생존률은 메주,고추기름 혼합투여군이 대조군에 비해 약 20% 감소하였 으며,소량 투여군에 비해 대량 투여군이 생존률이 낮았다. 2. 실험동물의 체중 변화는 대조군에 비하여 투여군이 체중감소를 나타내었고 대량 투여군과 소량 투여군 사이에는 유의적인 차이가 없었다. 3. 실험동물의 식이 섭취량은 대조 군에 비하여 투여군이 낮았으며,식이 효율은 오히려 투여군이 증가하는 경향을 나타내었다. 4.위점막에 대한 조직학적 검사 소견은 실험군 모두 위암 발생이 나타나지 않았다. Aflatoxin has been known as a strong hepatocarcinogen in experimental animals and possibly in human. And it has been known to have potential effect on gastric cancer. According to recent domestic studies about 10% of maejoo contain aflatoxin. Red pepper has been used for red pepper taste, kimchi, and other meals as most important condiments. The experimental study was performed in 182 wistar rats for 29 weeks. They were devided into 7 groups; Af B₁, P₁, P₂, M₁, M₂, P₁M₁, and P₂M₂. Group P₁, P₂was treated 1%, 3% red pepper oil and aflatoxin B₁, as a large dose group. Group M₁, M₂ was supplemented 5%, 10% maejoo and aflatoxin B₁. Group P₁M₁, P₂M₂ was given 1%, 3% red pepper oil, 5%, 10% maejoo and aflatoxin B₁. Aflatoxin B₁(10㎍ per day in Dimethy Sulfoxide) was injected big oral intubation 50 times. The results of this study were summerized as following. 1. The final survival rate at 29th week of the rats treated with maejoo were lower than red pepper treated group significantly. And the maejoo and red pepper large dose group showed the lowest survival rate. 2. The food intake of red pepper large does group was lowest in all experimental group significantly. And the food intake of large dose groups were lower than small dose group. 3. The body weight gain of red pepper and maejoo treated groups(P₁M₁,P₂M₂) had lowest body weight gain at 29th week. 4. The upper gastro intestinal cancers did not appeared in all experimental groups.

초등학교의 지역간 시력차이에 관한 연구 : 대구 및 영천지역을 중심으로

진미선,석귀덕,신임희 韓國學校保健學會 2001 韓國學校保健學會誌 Vol.14 No.2

The study was carried out to estimate the prevalence and possible causes of refractive errors in primary school children. At one primary school in urban Daegu, one in the medium-sized city of Yongcheon and 2 in rural areas, children wearing glasses and children with visual acuity of less than 0.7 were given our questions. 354 out of 378 children responded to our questions. The research was done from March 2000 to February 2001. The data were analyzed by percentage, χ2 test, t-test, ANOVA and Scheff method. Children with eyesight problems were more prevalent in urban areas than rural areas. The lack of luminosity during reading (p=0.015), length of reading time (p=0.08) and posture which watching TV (p=0.023) appeared leading causes of progressing myopias. The visual impairment caused by refractive errors may affect the mental and physical activity of primary school children and lead to social isolation, loneliness and depression. However, little attention may be paid by professionals engaged in providing health care to the children. Once we have recognized the impact of visual impairment, we may be in a better position to prevent progressing refractive errors.

의료 질 향상 사업의 성공요인과 실패요인

최귀선,이선희,조우현,강혜영,채유미 한국의료QA학회 2001 한국의료질향상학회지 Vol.8 No.2

Background : To propose effective strategies for successful implementation of QI in health care institutions, by identifying facilitating factors and barriers to conducting QI programs. Methods : In order to examine empirical evidence on the success factors or barriers to QI implementation in hospitals, a literature study was performed on the basis of MEDLINE search. Among the identified literature. 13 provided reliable findings and basis comprehensive discussion on this issue and thus were selected for in-depth analysis. A mailed questionnaire survey was conducted for hospital CEOs and QI directors of hospitals with 400 beds or greater to investigate what attributes of their organizations they perceived as success factors or obstacles to QI implementation. Result : The analysis of selected literature and survey results presented that the primary factors considered to be most important as successful implementation of QI were: strong support from hospital CEOs, setting higher priority for QI activities, continuous and persistent efforts in QI activities, and active participation of clinical staffs. The barriers identified in this study were : the lack of orientation and understanding of QI concepts, low level of interest and participation of physician in QI programs, the lack of evaluation and rewarding system for QI activities. Conclusion : By identifying factors that affect facilitation of QI, the study results will be of great use for either institutions being in the early stage of evolving QI or those looking for better strategies to achieve more active and persistent QI implementation in their institutions.

주부들의 심리적 자각 증세와 혈청 칼슘 및 마그네슘 농도와의 관련성

박귀선,김현주,한진숙 東亞大學校 附設 生活科學硏究所 2003 생활과학연구 논문집 Vol.11 No.-

This study was conducted to investigate the relationship of serum calcium and magnesium levels to depression and anxiety symptoms in 80 homemakers. Fasting blood samples were collected and serum calcium and magnesium concentrations were measured. At the same time psychological conditions of subjects were estimated by STAI-S(State Trait Anxiety Inventory-State) questionnaire. Resulting from psychological test, number of high score group(HSG) were higher than those of low score group(LSG) and 85% of subject in 32-38's were belonged to HSG. Mean serum concentrations of calcium and magnesium in HSG were significantly lower than those in LSG. Almost low calcium and magnesium levels of subjects appealed to depression and anxiety symptoms. Depression and anxiety scores in subjects who have been calcium supplementation were significantly lower than those in before calcium supplementation. After calcium supplementation in HSG, depression and anxiety scores were significantly decreased and serum calcium and magnesium levels were significantly increased to normal ranges. This results suggested that psychological conditions of homemaker might be affected by serum calcium and magnesium levels.

아암 레스트 메카니즘 개발에 관한 연구

박귀선,김희석,이춘만 國立 昌原大學校 産業技術硏究所 2000 産技硏論文集 Vol.14 No.-

Fixed arm rest on present cars causes unstable driving pose and is not proper to support a arm during long time driving. So there could be problems for the safety driving. Thus, considering above defect, it can be reduced fatigue by dispersing body pressure concentrated on a waist and a bottom during driving using the arm rest mechanism. The research herein is for a long way safety driving and perceives the flexible operation suited for the steering motion. The feature in this research is that having operation set for good rest without any difficulty by putting a arm on the arm rest during steering. The arm rest has been designed for the fold type so being easy when get on and off a car and giving very useful effect to driver's long way safety driving.

칼슘섭취가 60세 전후 성인의 우울 및 불안 성향에 미치는 영향에 관한 사례연구

박귀선,이경애 東亞大學校 附設 生活科學硏究所 2003 생활과학연구 논문집 Vol.11 No.-

This study was to investigate 1) the correlation of serum Ca, with depression and anxiety; and 2) the effect of Ca intake on those symptoms. The subjects were three females and two males who were 53-66 years old with the severe subjective symptoms of depression and anxiety. They have taken more than twice Ca of RDA(recommended dietary allowances for Koreans) daily for 6 months(dietary treatment). The prestudy Ca intake of the subjects was low: 60% of RDA for Koreans. Their serum Ca concentration was also low: 6.67±0.15mg/dl before the dietary treatment. They expressed severe depression and anxiety, with high self scores in a psychological test. Their serum Ca concentration increased to 8.32±0.17mg/dl after six months of dietary treatment, while the symptoms of depression and anxiety decreased significantly after two months and nearly disappeared after six months. This result seemed to be an effect of the dietary high Ca intake. Serum Ca and the psychological states of depression and anxiety correlated negatively, and the coefficients of determination were high in the results of linear regression analysis of depression and anxiety by serum Ca. Therefore the serum Ca concentration could be a good marker to predict depression or anxiety relatively well. The continuous high Ca intake could decrease the probability of developing depression or anxiety and mitigate their symptoms because serum Ca concentration increased, while the state of depression and anxiety decreased with the increased Ca intake.

사상 체질별로 분류한 여대생의 식사내용이 혈청과 뇨중 성분치에 미치는 영향에 대한 연구

박귀선,한진숙,김현주 동아시아식생활학회 1998 동아시아식생활학회지 Vol.8 No.3

This study was conducted to compare the serum composition and urinary excretion in four institutional groups and the effects of intakes of good foods and harmful foods according to the Sasang constitution for a short time on serum and urine composition. The contitutions of 33 female students were classified by O-ring test and muscular strength test according to the Sasang constitution. The number of each institutional group was So-yang-in 11, So-em-in 10 and Tae-em-in 12. No subject belonged to Tae-yang-in. There were no significant differences among contitutional groups in the values of most serum composition and urinary excretion. Serum levels of total cholesterol, glucose, calcium and phosphorus in Tae-em-in was the highest among groups and the level of albumin and total protein in So-em-in was highest. The values of serum compositions changed after the 33 subjects took good foods and then harmful foods according to The Sasang constitution for a short time(5 days). Dietary behavior of the subjects had some effects among the constitutional groups in the values of most serum composition and urinary excretion. But the effects of dietary behavior on the serum composition and urinary excretion showed various trends in the four institutional groups.

구원과 십자가에 대한 사도 바울의 이해

이귀선 서울여자대학교 1981 서울여자대학논문집 Vol.- No.10

유산소 운동이 비만인의 신체구성과 혈중지질대사에 미치는 영향

전종귀,김선호 忠南大學校體育科學硏究所 2002 體育科學硏究誌 Vol.20 No.1

The purpose of this experiment was to recognize the influence executed aerobics for eight weeks, and what kind of influence were having on body compositions, metabolism of blood lipids according to sports disposition period, and the object of this experiment was university students who were being obesity. The object of this experiment was 12-man-university students who were having at least 25% deal of fat mass(fat%), had no special sport experiences, and their health state was desirable, and they were divided two groups, one was exercise-group and the other was non-exercise-group, each group had 6 members. By pre-experiment, the experiment was executed on treadmill during 50 minutes with HRmax 75%. Blood gathering was done when the object was stability and after the exercise immediately, and the blood which were gathered, was analyzed for blood lipid. After 8 weeks aerobics, though exercise group lessen their weight, fat mass, and the rate of fat in comparison with opponent, they didn't greatly differ from non-exercise group in body compositions. However, after the aerobics executed for many hours, in comparison with non-exercise-group, exercise-group had been increased the rate of HDL, but decreased the rate of TC and TG. The result of this experiment is the aerobics effects body composition, blood lipid and makes them are changed. The reason is aerobics makes our body to be increased ability of metabolism and lipolysis, and amount of muscles, adipose tissue, and the rate of energy consumption, and using of adipose. Therefor, aerobic that execute for many hours increase the energy consumption, so it prevents obesity phosphorus from chronic disease. In conclusion, aerobics is an effective exercise to maintain our good health.

聖書的 神秘主義

李貴善 서울여자대학교 1980 서울여자대학논문집 Vol.- No.9