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Park, Kiho,Kim, Do Yeon,Yang, Dae Ryook American Chemical Society 2017 INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH - Vol.56 No.50
<P>This study proposed and investigated a new pressure-retarded membrane distillation (PRMD) for simultaneous production of water and electricity. The PRMD process was designed by combining the concepts of direct contact membrane distillation (DCMD) and pressure-retarded osmosis (PRO) processes in a single membrane module. A mathematical model for the PRMD process was developed, and the performances of energy generation and water production were estimated and compared to the results of the DCMD process. It was found that the PRMD process can save energy by producing electricity from a hydro-turbine, but the water production rate is slightly less than the DCMD process. Also, the effects of operating conditions and membrane properties were analyzed, and the best conditions were investigated. By applying the best available membrane technology, the PRMD process can save about 0.1738 kWh/m<SUP>3</SUP> with about only 3% sacrifice of fresh water production compared to the DCMD process at the same basis. Thus, the PRMD process can be used as a multifunctional system for producing water as the DCMD process and electricity as the PRO process at the same time, so it can be a self-sustained process when low-grade heat energy could be supplied.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/iecred/2017/iecred.2017.56.issue-50/acs.iecr.7b03642/production/images/medium/ie-2017-03642h_0015.gif'></P>
Park, Kiho,Kim, Do Yeon,Yang, Dae Ryook American Chemical Society 2016 INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH - Vol.55 No.26
<P>Continuous multistage mixed suspension and mixed product removal (MSMPR) crystallization processes are useful for the large-scale production of particulate systems. However, the design of operating strategies to meet specific objectives and materials has not been completely investigated. In this work, the effect of important crystallization kinetic parameters on the optimal operating strategy was examined. The important parameters are the kinetic constants of the primary and secondary nucleation rates, the orders of the nucleation and growth rates, and the number of crystallizer stages. The analyses revealed that a drastic cooling strategy in the primary nucleation dominant region and linear cooling in the secondary nucleation dominant region are best for producing large particle sizes. A stage number of similar to 3 is effective in both regions. These results can be utilized determine the operating strategy for a process, if the crystallization kinetic parameters are already roughly known.</P>
Identification of Novel Mutations in Adenosine Deaminase Gene in Korean Leukemia Patients
Kiho Park(박기호) 한국생명과학회 2010 생명과학회지 Vol.20 No.3
백혈병은 조혈모세포의 비정상적인 증식에 의해 일어나서 질환이고, adenosine deaminase (ADA) 유전자는 백혈병의 약물 작용점으로 중요하다. 이러한 연구의 일환으로 한국인 백혈병 환자 20명의 ADA 유전자의 변이를 조사하기 위해 혈액 genomice DNA를 추출하여 염기서열을 결정하였다. 그 결과 nonsense 변이인 F101F 하나, missense 변이 E260K, D8Y 각각 하나, 그리고 외국에서는 보고되지 않은 것으로 정상인에서 IVS6-52에 GC가 도입된 것을 확인하였다. 백혈병 환자와 유전자 변이간에 통계학적인 차이점은 없지만 이러한 연구는 앞으로 백혈병의 진단 마크 개발에 도움이 될 것으로 사료된다. Leukemia is the abnormal increase of hematopoietic progenitor cells in tissues, resulting in anemia, increased susceptibility to infection and impaired blood clotting. The adenosine deaminase (ADA) gene is an important druggable target for the treatment of leukemia patients. Genetic and molecular analyses were performed to determine the effects of ADA gene mutations in 20 leukemia patients in the Korean population. To analyze the relationship between genotype and phenotype, the ADA genomic DNAs - including 1,092 bp of 12 exons and partial intron sequences flanking each exon - were sequenced and compared. In this study, the known mutations in other diseases, more than 50 mutations already reported in patients with severe combined immunodeficiency disease (SCID) and autism, were not found, but two novel mutations in leukemia patients were discovered. They include one nonsense mutation (A>C at nt position 478, F101F) and one missense mutation (G>A at nt position 778, E260K). One missense mutation (G>A at nt position 22, D8Y) was also detected in 20 normal control patients (allelic frequency of 7.5%). Interestingly, subjects in the Korean population retained 2 bp insertion at the intron 6 (IVS6-52insGC), something that has never been shown in other populations. The genetic study to find out the correlation between the mutant alleles and leukemia patients revealed no association statistically (p>0.05). The mutation found in leukemia needs further study to determine its possibility as a molecular marker for the diagnosis of leukemia.
The Causal Relationship between the Acceptance Attitudes and the Expected Effects of Smart Work
Park, Kiho Korea Data Strategy Society 2014 Journal of information technology applications & m Vol.21 No.1
This paper explores the causal relationship between acceptance attitudes and expected effects of smart work. With the rapid development of smart technologies, lots of organizations try to innovate in the conventional working styles for maximizing organizational effectiveness and efficiency. Although many organizations wish to foster smart working environment, they don't have confidence in detailed action plans and effects from it. Therefore, this study that explores the causal relationship between acceptance attitudes and effects may have crucial meaning to organizations pursuing smart work. In this research empirically conducted by questionnaire survey, the acceptance attitudes as predictors and the expected effects of smart work as influenced variables were used. This research analyzed 118 collected data and multiple regression analysis. As a result of analysis, teleworking shows the positive relations to all of dependent variables. And others have a positive or negative influence on effects of smart work. Results of this study may give implications to organizations that want to implement smart work environment.
Exploring the Difference in Acceptance of Smart Work among Levels of Leadership Styles
Park, Kiho Korea Data Strategy Society 2013 Journal of information technology applications & m Vol.20 No.4
According to the development of smart technologies such as smart phones, tablet PC, and SNS communication, the necessity of smart work that can change the working environments in organizations has been emphasized. However, while there are many organizations that wish to adopt smart technologies, there are those that have been skeptical until now about its potential success. Leaders may especially have different viewpoints concerning the efficacy and effectiveness of smart work depending on the industries, characteristics of the work, etc. Therefore, this research looks to investigate whether there may be differences between leaders (manager, project manager, supervisor, etc.) and non-leaders (team member, staff, etc.) group in accepting smart working through empirical and exploratory approaches.
Exploring the Difference in Acceptance of Smart Work among Levels of Leadership Styles
Kiho Park 한국데이타베이스학회 2013 Journal of information technology applications & m Vol.20 No.4
According to the development of smart technologies such as smart phones, tablet PC, and SNS communication, the necessity of smart work that can change the working environments in organizations has been emphasized. However, while there are many organizations that wish to adopt smart technologies, there are those that have been skeptical until now about its potential success. Leaders may especially have different viewpoints concerning the efficacy and effectiveness of smart work depending on the industries, characteristics of the work, etc. Therefore, this research looks to investigate whether there may be differences between leaders (manager, project manager, supervisor, etc.) and non-leaders (team member, staff, etc.) group in accepting smart working through empirical and exploratory approaches.
Kiho Park 한국데이타베이스학회 2010 Journal of information technology applications & m Vol.17 No.3
Many organizations have had deep interests in studies concerning leadership and in academic areas, in not only management but also psychology. Until now, leadership has been accentuated by managers or team leaders especially. Recently, however, the concept of self-leadership directing one's own activities through self-control or self-management is being focused on practices and in academia. This study is to investigate the influence between self-leadership strategies and learning performance in IT classes mediated by attitude of attendance focused on the social science students in a university. Research results can give us direction of task-taking attitudes in firms or learning attitudes in teaching organizations and implications to human resource managers who are in charge of improving learning performance or productivity.