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        Correlation between Vitamin B12 and Mental Health in Children and Adolescents: A Systematic Review and Meta-analysis

        Yongjun Tan,Li Zhou,Kaiqi Gu,Caihong Xie,Yuhan Wang,Lijun Cha,Youlin Wu,Jiani Wang,Xiaosong Song,Xia Chen,Hua Hu,Qin Yang 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.4

        To conduct the association between vitamin B12 and mental health in children and adolescents. Five databases were searched for observational studies in any language reporting on mental health and vitamin B12 levels or intake in children and adolescents from inception to March 18, 2022. Two authors independently extracted data and assessed study quality. Qualitative and quantitative analysis of data were performed. The review was registered in the PROSPERO database (CRD42022345476). Fifty six studies containing 37,932 participants were identified in the review. Vitamin B12 levels were lower in participants with autism spectrum disorders (ASD) (standardized mean difference [SMD], −1.61; 95% confidence interval [95% CI], −2.44 to −0.79; p < 0.001), attention deficit hyperactivity disorders (SMD, −0.39; 95% CI, −0.78 to −0.00; p = 0.049) compared with control group. Vitamin B12 intake were lower in participants with ASDs (SMD, −0.86; 95% CI, −1.48 to −0.24; p = 0.006) compared with control group, but showed no difference between depression group (SMD, −0.06; 95% CI, −0.15 to 0.03; p = 0.17) and the control group. Higher vitamin B12 intake were associated with lower risk of depression (odds ratio [OR], 0.79; 95% CI, 0.63−0.98; p = 0.034) and behavioral problems (OR, 0.83; 95% CI, 0.69−0.99; p = 0.04). The vast majority of included studies supported potential positive influence of vitamin B12 on mental health, and vitamin B12 deficiency may be a reversible cause for some mental health disorders in children and adolescents.

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        The Constructs of the Lazarus and Folkman’s Stress-Appraisal-Coping Theory as Predictors of Subjective Well-Being in College Students During the Ongoing COVID-19 Pandemic

        Jia Rung Wu,Kanako Iwanaga,Fong Chan,Wu Hu,Kaiqi Zhou,Xiangli Chen,Chetwyn C. H. Chan,Timothy N. Tansey 한국상담학회 2023 Journal of Asia Pacific counseling Vol.13 No.2

        The COVID-19 pandemic has had significant adverse effects on the mental health of college students around the world. The purpose of the present study was to examine the constructs of Lazarus and Folkman’s stress-appraisal-coping theory as predictors of subjective well-being in Chinese college students during the ongoing COVID-19 pandemic. Participants included 244 Chinese college students. The final hierarchical regression model accounted for 71% of the variance in subjective well-being scores, a large effect size. In the final model, positive stress appraisal, hope, core self-evaluations and resilience remain significant after controlling for other variables. Coping flexibility were significant at the zero-order correlation level and at the step, it was entered into the equation. The effect of perceived stress dissipated in the presence of the positive person-environment contextual variables. Findings provide strong empirical support for the use of positive person-environment contextual variables as a stress management and subjective well-being model for college students during and after the COVID-19 pandemic. Findings can be used to guide counselors, psychologists, and psychiatrists in college health services in the selection of brief screening psychological instruments and empirically supported psychosocial and counseling interventions to help college students develop character strengths, positive attitudes, and coping skills to effectively cope with COVID-related challenges and stressors and possible future outbreaks of novel contagious diseases and crisis situations.

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