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A Modified Single Sampling Plan for the Inspection of Attribute Quality Characteristics
J. Subramani,S. Balamurali 대한산업공학회 2016 Industrial Engineeering & Management Systems Vol.15 No.1
In this manuscript, a modified single sampling plan is proposed for the inspection of products in which the nonconforming items can be classified in to two categories namely critical and non-critical; and explained with the help of industrial example. The operating procedure of this plan is also proposed and the performance measures such as the probability of acceptance, average sample number, average total inspection and average out going quality are also derived. The optimal parameters are determined which will have minimum sample size. The efficiency of the proposed plan is also discussed over the conventional single sampling plan. The extensive tables for selecting a modified single sampling plan based on AQL and LQL are provided for both Binomial and Poisson distributions and explained with the help of industrial data.
A Modified Single Sampling Plan for the Inspection of Attribute Quality Characteristics
Subramani, J.,Balamurali, S. Korean Institute of Industrial Engineers 2016 Industrial Engineeering & Management Systems Vol.15 No.1
In this manuscript, a modified single sampling plan is proposed for the inspection of products in which the nonconforming items can be classified in to two categories namely critical and non-critical; and explained with the help of industrial example. The operating procedure of this plan is also proposed and the performance measures such as the probability of acceptance, average sample number, average total inspection and average out going quality are also derived. The optimal parameters are determined which will have minimum sample size. The efficiency of the proposed plan is also discussed over the conventional single sampling plan. The extensive tables for selecting a modified single sampling plan based on AQL and LQL are provided for both Binomial and Poisson distributions and explained with the help of industrial data.
The Effect of Stocking Density on Stress Related Genes and Telomeric Length in Broiler Chickens
Beloor, J.,Kang, H.K.,Kim, Y.J.,Subramani, V.K.,Jang, I.S.,Sohn, S.H.,Moon, Yang Soo Asian Australasian Association of Animal Productio 2010 Animal Bioscience Vol.23 No.4
To be economically profitable, the poultry industry demands an increase in stocking density, which could adversely affect chicken welfare. The current study was performed to investigate the effect of stocking density on stress-related, heat shock protein genes (HSP70 and HSP90), 3-hydroxyl-3-methyl-glutaryl coenzyme A reductase (HMGCR) gene and telomere length in broiler chickens. Seven-day-old broiler chickens were housed at High (0.0578 $m^2$/bird), Standard (0.077 $m^2$/bird) and Low (0.116 $m^2$/bird) stocking densities with 8 replicates each until 35 d of age. The growth performance, such as body weight gain and average daily feed intake, was found to be significantly (p<0.05) higher in the Low density group, but these parameters did not show any difference between the High and Standard groups. Other growth performance, such as feed conversion ratio and final feed intake, showed no difference among the treated groups. The expression levels of HSP70 and HMGCR were found to be elevated with the increase of stocking density. The expression level of these genes was significantly (p<0.05) higher in the High density stocked group compared with the other groups, whereas the expression levels were not significantly different between the Low and Standard groups. The expression levels of HSP90 did not show any significant changes among the treated groups. The telomeric length of the birds housed in High density was reduced significantly (p<0.05) when compared to that of the birds in Low density. These results clearly indicate that birds stocked at high density show physiological adaptive changes indicative of stress at gene transcriptional and telomere levels.
Chick age prediction by telomeric DNA quantification
Y. J. Kim,V. K. Subramani,S. H. Lee,N. E. Choi,S. H. Sohn 한국가금학회 2008 한국가금학회 정기총회 및 학술발표회 Vol.25 No.-
This study aims to investigate and establish a telomere based bio-marker for the chicken. For the purpose we studied the amount of telomeric DNA in chicken blood lymphocytes and compared them across age, between sex and among breeds. The lymphocytes of Korean Native Chicken and White Leghorn were collected and the amount of telomeres was analyzed by Quantitative Fluorescent In Situ Hybridization(Q-FISH) using the telomeric DNA probe. We found that the amount of telomeric DNA decreased significantly with age, and females showed significantly higher amount than their male counterparts. In additions. the amount of telomeric DNA in Korean Native Chick breed was significantly higher than that of White Leghorn breed. We also establish age prediction equations by studying relationship between age and the amount of telomere in chickens using regression analysis.
Kim, Y.J.,Subramani, V.K.,Sohn, S.H. Asian Australasian Association of Animal Productio 2011 Animal Bioscience Vol.24 No.5
Telomeres are special structures at the ends of eukaryotic chromosomes. Vertebrate telomeres consist of tandem repeats of conserved TTAGGG sequence and associated proteins. Birds are interesting models for molecular studies on aging and cellular senescence because of their slow aging rates and longer life spans for their body size. In this longitudinal study, we explored the possibility of using telomeres as an age-marker to predict age in Single Comb White Leghorn layer chickens. We quantified the relative amount of telomeric DNA in isolated peripheral blood lymphocytes by the Quantitative Fluorescence in situ Hybridization technique on interphase nuclei (IQ FISH) using telomere-specific DNA probes. We found that the amount of telomeric DNA (ATD) reduced significantly with an increase in chronological age of the chicken. Especially, the telomere shortening rates are greatly increased in growing individuals compared to laying and old-aged individuals. Therefore, using the ATD values obtained by IQ FISH we established the possibility of age prediction in chickens based on the telomere theory of aging. By regression analysis of the ATD values at each age interval, we formulated an equation to predict the age of chickens. In conclusion, the telomeric DNA values by IQ FISH analyses can be used as an effective age-marker in predicting the chronological age of chickens. The study has implications in the breeding and population genetics of poultry, especially the reproductive potential.