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RISS 인기검색어
- 검색키워드
- 저자 : Hwa-YoungYoun (검색결과 5 건)
- 무료
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Development of Non-Invasive Fecal PCR Assay for Detecting the Helicobacter Species Infection in Dogs
Cheol-YongHwang,Hwa-YoungYoun,Hong-RyulHan 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.3
This study was conducted to develope noninvasive fecal PCR assay for detecting the Helicobacter species in dogs. From the DNA isolated from fecal samples, and a region of the 16S rRNA gene conserved among Helicobacter spp. was amplified. In comparison with gastric biopsy test, the fecal PCR assay showed high specificity (100%) and sensitivity (96%). The prevalence of Helicobacter spp. infection in privately owned pet dogs in Korea determined by the fecal PCR assay was 72.1%. The fecal PCR assay determined in this study can be a new noninvasive test for detecting Helicobacter spp. infection in dogs.
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Application of Receiver Operating Characteristic(ROC) Curves for Clinical Diagnostic Tests
Son-IlPak,Hee-SeungKoo,Cheol-YongHwang,Hwa-YoungYoun 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.3
Diagnostic tests often require the determination of cut-off values that discriminate uninfected from infected individuals. The receiver operating characteristic (ROC) curve has been frequently used to attain this purpose and gives a representation of diagnostic accuracy (sensitivity and specificity) of a prediction model when varying the cut-point of a decision rule on a whole spectrum. We have written and tested a visual basic application program in EXCEL for maximum likelihood estimation of a binormal ROC curve, which also computes univariate statistics of a diagnostic test employed. Examples applying for computed tomographic images in radiology and methicillin-resistant Staphylococcus aureus research are given to illustrate this approach. This stand-alone module is available from the first author on request.
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Aerobic Antimicrobial Susceptibility Patterns of Bacteria Isolated from Dogs
HeeYoo,Se-WonPark,Cheol-YongHwang,Hwa-YoungYoun,Hong-RyulHan 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.3
Isolation and identification of causative microorganisms and susceptibility testing are important in selecting appropriate antimicrobial agent. The purpose of this study was to determine the antimicrobial susceptibility patterns and identification of bacteria for the selection of a therapeutic antibiotic agent for treatment. Specimens were cultured aerobically from dog patients brought to the veterinary medical teaching hospital of Seoul National University between July 1999 and September 2000. A total of 157 isolates were from skin(63), urine(45), ear canal(31) and conjunctiva(18). The result is that the most common organisms isolated from dog patients were S. intermedius was the most common isolates from the skin, ear canal, and conjunctiva. E. coli was the most common isolated from urine. Most of gram-positive isolates were resistant to ampicillin(80.6%), erythromycin(68.8%), penicillin(86.2%), tetracycline(89.2%). Otherwise most of gram-negative isolates were resistant to ampicillin(73.4%), trimethoprim-sulfa(53.3%). E. coli was resistant to ciprofloxacin(61.5%), piperacillin (69.2%). Antimicrobial susceptibility pattern by the sampling site was not remarkably different except S. aureus isolated from urine.
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Chronic Lymphocytic Leukemia in a Dog
Seong-WooJung,EulSooChoi,Jong-BokLee,Cheol-YoungHwang,Hwa-youngYoun,Chang-WooLee,Houng-RyulHan 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.4
Chronic lymphocytic leukemia is a general disease that evolves over a longer duration and is characterized by more mature and well-differentiated lymphocytes in blood and bone marrow than those seen in acute leukemia. This report presents a 2-year-old mix neutered male dog with seizure, ascites, and transmissible venereal tumor. Diagnostic works-up concluded chronic lymphocytic leukemia. Chemotherapy composed of chlorambucil and prednisolone has been applied to the patient until now. Remission of almost manifestations was achieved, and the quality of life improved.
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Recombinant Tissue Plasminogen Activator Therapy for Aortic Thromboembolism in Four Dogs
한세명,Ji-Ye Lee,Kyeong Kweon,최민철,윤정희,Hwa-YoungYoun 한국임상수의학회 2016 한국임상수의학회지 Vol.33 No.3
Four dogs were brought to the Veterinary Medicine Teaching Hospital of Seoul National University (VMTH SNU) with a history of hind limb ataxia, three with pain, one without pain. Three of the four showed weak to absent femoral pulses and cold extremities. Thromboembolism was identified by ultrasonography in the external and/or internal iliac arteries. A thrombolytic agent, recombinant tissue plasminogen activator (rt-PA), was administered (0.5-1 mg/kg, every 60-120 min, 3-5 doses). Two dogs (Cases 2 and 3), which were instantly provided rt-PA treatment, survived 6 and 17 months, respectively, although hematemesis and hematochezia were observed during treatment. In the other two dogs (Cases 1 and 4), rt-PA was administered 4 and 28 days after the appearance of pelvic limb symptoms, which may have limited the benefits of the treatment. When rt-PA treatment is instituted instantly and the side effects are monitored thoroughly during treatment, a good prognosis might be expected in canine aortic thromboembolism. For this reason, we suggest that rt-PA treatment should be initiated immediately if thromboembolism is identified.
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