An Asymmetric Key-Based Security Architecture for Wireless Sensor Networks

Haque, Md. Mokammel,Pathan, Al-Sakib Khan,Hong, Choong-Seon,Huh, Eui-Nam Korean Society for Internet Information 2008 KSII Transactions on Internet and Information Syst Vol.2 No.5

In spite of previous common assumptions about the incompatibility of public key cryptography (PKC) schemes with wireless sensor networks (WSNs), recent works have shown that they can be utilized for such networks in some manner. The major challenge of employing a PKC-based scheme in a wireless sensor network is posed by the resource limitations of the tiny sensors. Considering this sensor feature, in this paper we propose an efficient PKC-based security architecture with relatively lower resource requirements than those of previously proposed PKC schemes for WSN. In addition, our scheme aims to provide robust security in the network. Our security architecture comprises two basic components; a key handshaking scheme based on simple, linear operations and the derivation of a decryption key by a receiver node. Our architecture enables node-to-base-station and node-to-node secure communications. Analysis and simulation results show that our proposed architecture ensures a good level of security for network communications, and can be effectively implemented with the limited computational, memory, and energy budgets of current-generation sensor nodes.

Matrix Metalloproteinase-2 -1306 C>T Gene Polymorphism is Associated with Reduced Risk of Cancer: a Meta-analysis

Haque, Shafiul,Akhter, Naseem,Lohani, Mohtashim,Ali, Arif,Mandal, Raju K. Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3

Matrix metalloproteinase-2 (MMP2) is an endopeptidase, mainly responsible for degradation of extracellular matrix components, which plays an important role in cancer disease. A single nucleotide polymorphism (SNP) at -1306 disrupts a Sp1-type promoter site. The results from the published studies on the association between MMP2 -1306 C>T polymorphism and cancer risk are contradictory and inconclusive. In the present study, a meta-analysis was therefore performed to evaluate the strength of any association between the MMP2 -1306 C>T polymorphism and risk of cancer. We searched all eligible studies published on association between MMP2 -1306 C>T polymorphism and cancer risk in PubMed (Medline), EMBASE and Google Scholar online web databases until December 2013. Genotype distribution data were collected to calculate the pooled odds ratios (ORs) and 95% confidence intervals (95%CIs) to examine the strength of the association. A total of 8,590 cancer cases and 9,601 controls were included from twenty nine eligible case control studies. Overall pooled analysis suggested significantly reduced risk associated with heterozygous genotype (CT vs CC: OR=0.758, 95%CI=0.637 to 0.902, p=0.002) and dominant model (TT+CT vs CC: OR=0.816, 95%CI=0.678 to 0.982, p=0.032) genetic models. However, allelic (T vs C: OR=0.882, 95%CI=0.738 to 1.055, p=0.169), homozygous (TT vs CC: OR=1.185, 95%CI=0.825 to 1.700, p=0.358) and recessive (TT vs CC+CT: OR=1.268, 95%CI=0.897 to 1.793, p=0.179) models did not show any risk. No evidence of publication bias was detected during the analysis. The results of present meta-analysis suggest that the MMP2 -1306 C>T polymorphism is significantly associated with reduced risk of cancer. However, further studies with consideration of different populations will be required to evaluate this relationship in more detail.

G894T and 4a/b Polymorphisms of NOS3 Gene are Not Associated with Cancer Risk: a Meta-analysis

Haque, Shafiul,Mandal, Raju K,Akhter, Naseem,Panda, Aditya K,Hussain, Arif,Khan, Saif,Lohani, Mohtashim Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7

Endothelial nitric oxide synthase (eNOS or NOS3) produces nitric oxide and genetic polymorphisms of NOS3 gene play significant roles in various processes of carcinogenesis. The results from published studies on the association between NOS3 G894T and NOS3 intron 4 (4a/b) polymorphisms and cancer risk are conflicting and inconclusive. However, i n order to assess this relationship more precisely, a meta-analysis was performed with PubMed (Medline), EMBASE and Google web searches until February 2014 to select all published case-control and cohort studies. Genotype distribution data were collected to calculate the pooled odd ratios (ORs) and 95% confidence intervals (CIs) to evaluate the strength of association. A total of 10,546 cancer cases and 10,550 controls were included from twenty four case-control studies for the NOS3 G894T polymorphism. The results indicated no significant association with cancer risk as observed in allelic (T vs G: OR=1.024, 95%CI=0.954 to 1.099, p=0.508), homozygous (TT vs GG: OR=1.137, 95%CI=0.944 to 1.370, p=0.176), heterozygous (GT vs GG: OR=0.993, 95%CI=0.932 to 1.059, p=0.835), recessive (TT vs GG+GT: OR=1.100, 95%CI=0.936 to 1.293, p=0.249) and dominant (TT+GT vs GG: OR=1.012, 95%CI=0.927 to 1.105, p=0.789) genetic models. Similarly, a total of 3,449 cancer cases and 3,691 controls were recruited from fourteen case-control studies for NOS3 4a/b polymorphism. Pooled results indicated no significant association under allelic (A vs B: OR=0.981, 95%CI=0.725 to 1.329, p=0.902), homozygous (AA vs BB: OR=1.166, 95%CI=0.524 to 2.593, p=0.707), heterozygous (BA vs BB: OR=1.129, 95%CI=0.896 to 1.422, p=0.305), dominant (AA+BA vs BB: OR=1.046, 95%CI=0.779 to 1.405, p=0.763) and recessive (AA vs BB+BA: OR=1.196, 95%CI=0.587 to 2.439, p=0.622) genetic contrast models. This meta-analysis suggests that G894T and 4a/b polymorphisms of NOS3 gene are not associated with increased or decreased risk of overall cancer.

Targeting the microglial NLRP3 inflammasome and its role in Parkinson's disease

Haque, Md. Ezazul,Akther, Mahbuba,Jakaria, Md.,Kim, In‐,Su,Azam, Shofiul,Choi, Dong‐,Kug John WileySons, Inc. 2020 Movement disorders Vol.35 No.1

<P><B>Abstract</B></P><P>Excessive activation of microglia and subsequent release of proinflammatory cytokines play a crucial role in neuroinflammation and neurodegeneration in Parkinson's disease (PD). Components of the nucleotide‐binding oligomerization domain and leucine‐rich‐repeat‐ and pyrin‐domain‐containing 3 inflammasome complex, leucine‐rich‐repeat‐ and pyrin‐domain‐containing 3, caspase‐1, and apoptosis‐associated speck‐like protein containing a CARD, are highly expressed in activated microglia in PD patient brains. Findings suggest that neurotoxins, aggregation of α‐synuclein, mitochondrial reactive oxygen species, and disrupted mitophagy are the key regulators of microglial leucine‐rich‐repeat‐ and pyrin‐domain‐containing 3 inflammasome activation and release of interleukin‐1β and interleukin‐18 caspase‐1‐mediated pyroptotic cell death in the substantia nigra of the brain. Although this evidence suggests the leucine‐rich‐repeat‐ and pyrin‐domain‐containing 3 inflammasome may be a potential drug target for treatment of PD, the exact mechanism of how the microglia sense these stimuli and initiate leucine‐rich‐repeat‐ and pyrin‐domain‐containing 3 inflammasome signaling is unknown. Here, the molecular mechanism and regulation of microglial leucine‐rich‐repeat‐ and pyrin‐domain‐containing 3 inflammasome activation and its role in the pathogenesis of PD are discussed. Moreover, the potential of both endogenous and synthetic leucine‐rich‐repeat‐ and pyrin‐domain‐containing 3 inflammasome modulators, long noncoding RNA, microRNA to develop novel therapeutics to treat PD is presented. Overall, we recommend that the microglial leucine‐rich‐repeat‐ and pyrin‐domain‐containing 3 inflammasome can be a potential target for PD treatment. © 2019 International Parkinson and Movement Disorder Society</P>

Dose- and age-specific antioxidant responses of the mysid crustacean <i>Neomysis awatschensis</i> to metal exposure

Haque, Md. Niamul,Lee, Do-Hee,Kim, Bo-Mi,Nam, Sang-Eun,Rhee, Jae-Sung Elsevier 2018 Aquatic toxicology Vol.201 No.-

<P><B>Abstract</B></P> <P>Waterborne metals can adversely affect an organism’s innate defenses through oxidative stress. In the present study, the marine mysid <I>Neomysis awatchensis</I> was exposed to sublethal concentrations (1/10 and 1/5 of the median LC50s) of As, Cd, Cu, Pb, and Zn for 48 or 96 h at the juvenile and adult developmental stages, and the dose- and age-specific antioxidant defense system responses were characterized. Metal accumulation and modulation of four key antioxidant biomarkers, malondialdehyde (MDA), glutathione (GSH), superoxide dismutase, and catalase, were measured in juvenile and adult mysids. Based on LC50, level of metal toxicity was dependent on metal concentration, developmental stage, and the exposure duration. Intracellular MDA content was increased in the As-, Cu-, Pb-, and Zn-exposed juvenile mysids after exposure for 48 and/or 96 h, while increases in MDA content were observed in adult mysids following Cu and Zn exposure. Interestingly, GSH content was differentially modulated, where intracellular GSH levels decreased in juvenile mysids following Cd, Cu, Pb, and Zn exposure, but significantly increased in metal-exposed adult mysids, except for Pb exposure. The catalase and superoxide dismutase activities displayed similar stage-specific increases or decreases as also observed for the different GSH levels, suggesting that the susceptibility to and defense against metal-induced oxidative stress differed based on stage. Modulations in MDA and GSH content and enzymatic activity of the antioxidant defense system indicate that mysid antioxidant defense system factors are intimately connected during control of oxidative imbalances with different capacities at different developmental stages.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Evidence on the age-specific bioconcentration of five metals in the marine mysid was obtained. </LI> <LI> Age-specific relationship between metal dynamics and ecotoxicity between ages was observed. </LI> <LI> Oxidative stress was induced by metals and caused distinctive age-specific antioxidant response. </LI> </UL> </P>

USE OF A 3D RANS MODEL TO PREDICT STRATIFICATION EFFECTS RELATED TO FISH PASSAGE AT HYDROPOWER DAMS

HAQUE MD. MANJURUL,KOKEN METE,CONSTANTINESCU GEORGE,WEBER LARRY 한국수자원학회 2005 한국수자원학회 학술대회 Vol.2005 No.1

Safety Profile Assessment and Identification of Volatile Compounds of Krill Eupausia superba Oil and Residues Using Different Extraction Methods

Haque, A.S.M. Tanbirul,Kim, Seon-Bong,Lee, Yang-Bong,Chun, Byung-Soo The Korean Society of Fisheries and Aquatic Scienc 2014 Fisheries and Aquatic Sciences Vol.17 No.2

In this study, Krill Eupausia superba oil was extracted using different solvents and supercritical carbon dioxide (SC-$CO_2$). During SC-$CO_2$ extraction, the pressure was set at 40 MPa and temperatures ranged from $40^{\circ}C$ to $55^{\circ}C$. We examined the differences in volatile compounds and safety profiles among extraction methods. Volatile compounds were determined using the thermal desorption system integrated with gas chromatography-mass spectrometry (GC-MS). Heavy metal content was analyzed by inductively coupled plasma mass spectrometry (ICP-MS). According to our results 10 volatile compounds were identified in krill sample. After SC-$CO_2$ extraction of oil, the concentrations of volatile compounds decreased, but increased after solvent extraction. In krill, heavy metal concentrations remained within the permissible limit. Moreover, Zn and Fe which have health benefits were detected at high concentrations. During a 90 days storage period at different temperatures, microbial activity was found to be lowest in SC-$CO_2$ extracted residues. Thus, the quality of krill oil and the residues obtained using SC-$CO_2$ extraction was higher and the oil was safer than those obtained using conventional solvent extraction. These results can be applied to the food industry to maintain high quality krill products.

The Contribution of Non-conventional Microfinancing on Economic, Social and Household Empowerment of Women Borrowers in Malaysia

HAQUE, Tasnuba,SIWAR, Chamhuri,GHAZALI, Rospidah,SAID, Jamaliah,BHUIYAN, Abul Bashar Korea Distribution Science Association 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.2

This study investigated the effect of the Amanah Ikhtiar Malaysia (AIM) microfinancing on the economic, social, and household empowerment of women borrowers in Malaysia. The study used a quantitative approach based on primary data. For this study, the participants comprised 384 AIM borrowers from Terengganu, Kelantan, and Pahang in the east coast region of Malaysia. Purposive stratified random sampling was used as well as the Krejcie and Morgan method to count the number of samples. Descriptive statistics and the Women Empowerment Index (WEI) were used in the analysis. The study findings reveal that AIM microfinancing affects the economic, social, and household empowerment of women borrowers in Malaysia. However, in comparing the three categories, women enjoyed more freedom in social and household decision-making than in economic decision-making. The present study recommends policies for the successful and effective operation of microfinance programs by providing the necessary guidelines for the control of AIM loan for women borrowers; increasing income-generating activities, sufficient access of credit, and proper education for the borrowers; and giving economic freedom of choice with necessary skill training policymaking options for the government and NGOs with the aim to improve the total household income and empowerment of the microcredit borrowers in Malaysia.

Comparison of net global warming potential between continuous flooding and midseason drainage in monsoon region paddy during rice cropping

Haque, Md.M.,Kim, G.W.,Kim, P.J.,Kim, S.Y. Elsevier Scientific Pub. Co 2016 Field crops research Vol.193 No.-

<P>Midseason drainage is regarded as a key practice to suppress methane (CH4) emission from paddy soil during rice cultivation, but it can increase carbon dioxide (CO2) and nitrous oxide (N2O) emissions. However, the influences of midseason drainage practice on the net global warming potential (GWP) and greenhouse gas intensity (GHGI) of rice cropping systems is not well documented in the East monsoon region. In this field study, the effect of a 30-day midseason drainage practice from the 28th day after transplanting (DAT) to the 57th DAT on the three major greenhouse gas (GHG) fluxes and yield properties were compared with those of a continuous flooding system during rice cultivation in 2011 and 2012. The impact of midseason drainage on changing three GHG emissions was compared using the GWP value and GHG intensity (GHGI). Midseason drainage significantly reduced the net GWP scale by 46-50% of the continuous flooding, mainly due to 50-53% reduction of seasonal CH4 fluxes. Midseason drainage significantly increased N2O flux by 20-37% over the conventional flooding, but the influence of N2O emission increase on the net GWP scale was negligible. Midseason drainage significantly decreased soil C sequestration capacity by around 60% of continuous flooding, and then increased net GWP by 0.25-0.32 Mg CO2-eq. ha(-1) during rice cultivation. There was no significant difference of rice yield between two irrigation systems, and then midseason drainage can reduce GHGI by 50-56% of the continuous flooding. In conclusion, the midseason drainage practice during rice cultivation could be very useful soil management strategy to reduce GHG emission impact from lowland rice fields without impacting rice productivity. (C) 2016 Elsevier B.V. All rights reserved.</P>

Synthetic Methods and Applications of Silicon Nanowire: A Review

Haque, Md Hasanul,Sohn, Honglae The Basic Science Institute Chosun University 2017 조선자연과학논문집 Vol.10 No.2

In this review paper, we will discuss about the methods of synthesizing Si nanowires by Top-down and Bottom-up. Silicon nanowires have a lot of application on various fields such as Li ion batteries, solar cells, chemical and biological sensors. We will address some of the applications of silicon Nanowires.