http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Hypoallergenic and Physicochemical Properties of the A2 β-Casein Fraction of Goat Milk
Tae-Hwan Jung,Hyo-Jeong Hwang,Sung-Seob Yun,Won-Jae Lee,Jin-Wook Kim,Ji-Yun Ahn,Woo-Min Jeon,Kyoung-Sik Han2.6* 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.6
Goat milk has a protein composition similar to that of breast milk and contains abundant nutrients, but its use in functional foods is rather limited in comparison to milk from other sources. The aim of this study was to prepare a goat A2 β-casein fraction with improved digestibility and hypoallergenic properties. We investigated the optimal conditions for the separation of A2 β-casein fraction from goat milk by pH adjustment to pH 4.4 and treating the casein suspension with calcium chloride (0.05 M for 1 h at 25°C). Selective reduction of β- lactoglobulin and αs-casein was confirmed using sodium dodecyl sulphate-polyacrylamide gel electrophoresis and reverse-phase high-performance liquid chromatography. The hypoallergenic property of A2 β-casein fraction was examined by measuring the release of histamine and tumor necrosis factor alpha from HMC-1 human mast cells exposed to different proteins, including A2 β-casein fraction. There was no significant difference in levels of both indicators between A2 β-casein treatment and the control (no protein treatment). The A2 β-casein fraction is abundant in essential amino acids, especially, branched-chain amino acids (leucine, valine, and isoleucine). The physicochemical properties of A2 β-casein fraction, including protein solubility and viscosity, are similar to those of bovine whole casein which is widely used as a protein source in various foods. Therefore, the goat A2 β-casein fraction may be useful as a food material with good digestibility and hypoallergenic properties for infants, the elderly, and people with metabolic disorders.
Assessment of In Vitro Assay System for Thyroid HormoneDisruptors Using Rat Pituitary GH3 Cells
Hee Jin Kim1,Hae Young Park1,Jeonga Kim1,Il Hyun Kang2,Tae Sung Kim2,Soon Young Han2,Tae Seok Kang2,Kui Lea Park2,Hyung Sik Kim1 한국독성학회 2006 Toxicological Research Vol.22 No.4
The development of in vitro assays has been recommended to screening and test-ing the potential endocrine disruptors (EDs). These assay systems focus only on identifying thethe thyroid hormone (TH) disruptors. The aim of this study was to evaluate a test system to detectTH disruptors using rat pituitary tumor GH3 cells. The test system is based on the TH-dependentincrease in growth rate. As expected, L-3,5,3-triiodothyronine (T3) markedly induced a morphologicalchange in GH 3 cells from flattened fibroblastic types to rounded or spindle-shaped types. T3 stimu-lated GH3 cell growth in a dose-dependent manner with the maximum growth-stimulating effect9 M. In addition, T3 increased the release of growth hor-mone and prolactin into the medium of the GH3 cells culture. Using this assay system, the TH-dis-rupting activities of bisphenol A (BPA) and its related compounds were examined. BPA,dimethylbisphenol A (DMBPA), and TCI-EP significantly enhanced the growth of GH3 cells in therange of 1 × 10-5M to 1 × 10-6M concentrations. In conclusion, this in vitro assay system might bestandardization before it can be used as a broad-based screening tool.
Chaetoglobosin A, an Inhibitor of Bleb Formation on K562 Cells Induced by Phorbol 12,13-Dibutyrate
KO, HACK-RYONG,KIM, BO YEON,AHN, SOON-CHEOL,OH, WON KEUN,KIM, JIN-HEE,LEE, HYUN SUN,KIM, HWAN-MOOK,HAN, SANG-BAE,MHEEN, TAE0ICK,AHN, JONG-SEOG 한국미생물 · 생명공학회 1998 Journal of microbiology and biotechnology Vol.8 No.6
Park, Jong Il,Han, sang seop,Jeong, Tae Cheon,Roh, Jung Koo,Kim, Hyoung Chin,Kim, Jeong Hwan,Jeon, Yeong Joong,Kim, Dal Hyun,Kim,Je Hak,Park, Kwan Ha 한국응용약물학회 1997 Biomolecules & Therapeutics(구 응용약물학회지) Vol.5 No.1
The antigenic potential of CFA-001, cefazolin, a cephalosporin derivative produced by an enzymatic semisynthesis, was determined in Hartley guinea pigs. A battery of tests employed consisted of active systemic anaphylaxis (ASA), passive cutaneous anaphylaxis (PCA), and indirect hemagglutination test (IHA). The results were as follows: 1) In ASA, no signs attributable to anaphylaxis was observed in guinea pigs sensitized with CFA-001, whereas OVA-sensitized animals induced severe anaphylactic symptoms; 2) guinea pigs did not produce antibodies against CFA-001 when sensitized with or without Freund's complete adjuvant (FCA) in homologous PCA tests. Meanwhile, antibodies against ovalbumin (OVA) were clearly detected; 3) No CFA-001-specific hemagglutination was observed in the IHA using sera obtained from CFA-001-sensitized guinea pigs. These results suggest that CFA-001 has no antigenicity potential in guinea pigs.
Transcriptome analysis of the endangered freshwater pearl bivalve Cristaria plicata
Tae Hun Wang,Bharat Bhusan Patnaik,Se Won Kang,Hee Ju Hwang,So Young Park,Eun Bi Park,Jong Min Chung,Dae Kwon Song,Changmu Kim,Soonok Kim,Jun Sang Lee,Yeon Soo Han,Hong Seog Park,Yong Seok Lee 한국수산과학회 양식분과 2015 한국수산과학회 양식분과 학술대회 Vol.2015 No.10
Tae-Hun Kim,Ju-Han Lee,Minwon Park,In-Keun Yu,Chul-Sang Hwang,Gyeong-Hun Kim 한국산업정보학회 2014 한국산업정보학회 학술대회논문집 Vol.2014 No.1
This paper describes a power hardware in the loop simulation (PHILS)-based operational characteristic analysis of a kW class photovoltaic (PV) system with an active filter (AF) and static synchronous compensator (STATCOM) functions under variable load conditions. A 500 kW class PV generation system is modeled in a real time digital simulator. The AF and STATCOM control algorithm is applied to the controller of the fabricated DC/AC converter. Because it is hard to configure a large scale PV generation system for PHILS, a 10 kW PV array is applied for the 500 kW PV generation system in the real time digital simulator. The PHILS results verify that the PV-AF- STATCOM system compensated harmonic current and reactive power well. The developed PHILS system and control algorithm in this paper can effectively be applied to the power quality enhancement of real power systems.
CdSSe layer-sensitized TiO<sub>2</sub> nanowire arrays as efficient photoelectrodes
Sung, Tae Kwang,Kang, Jun Ha,Jang, Dong Myung,Myung, Yoon,Jung, Gyeong Bok,Kim, Han Sung,Jung, Chan Su,Cho, Yong Jae,Park, Jeunghee,Lee, Chang-Lyoul Royal Society of Chemistry 2011 Journal of materials chemistry Vol.21 No.12
<P>Complete composition-tuned CdS<SUB><I>x</I></SUB>Se<SUB>1−<I>x</I></SUB> alloy layers (avg. thickness = 50 nm) were deposited on pre-grown TiO<SUB>2</SUB> nanowires by the thermal vapor transport of CdS/CdSe powders, producing core–shell nanocable arrays. CdS<SUB><I>x</I></SUB>Se<SUB>1−<I>x</I></SUB> alloy nanowires were also synthesized with full composition tuning by the same method for comparison. The CdSSe nanowires consisted of Se-rich and S-rich pseudo binary phases, while the nanocable shell consisted of more complex multinary phases including CdSe and CdS. Remarkably, unique CdS–CdSSe–CdSe multishell structures were produced in the Se-rich composition range. The photoelectrochemical (PEC) cells fabricated using the as-grown nanocable arrays show higher solar photocurrents and hydrogen generation rates for the Se-rich shelled TiO<SUB>2</SUB> nanocable arrays. This suggests that the CdS–CdSSe–CdSe multishell structures increase greatly the PEC performance by producing novel band alignment for efficient electron–hole separation following enhanced visible-range photon absorption.</P> <P>Graphic Abstract</P><P>TiO<SUB>2</SUB>–CdS<SUB><I>x</I></SUB>Se<SUB>1−<I>x</I></SUB> core–shell nanocables were synthesized with complete composition tuning by a thermal vapor transport method. Unique CdS–CdSSe–CdSe multishell structures enhance the photocurrent and hydrogen generation rate of the photoelectrochemical solar cells. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c0jm03818k'> </P>