http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Hah, Yoon Soo,Lee, Kwang Suk,Choi, In Young,Lee, Ji Youl,Hong, Jun Hyuk,Kim, Choung-Soo,Lee, Hyun Moo,Hong, Sung Kyu,Byun, Seok-Soo,Lee, Seung Hwan,Rha, Koon Ho,Chung, Byung Ha,Koo, Kyo Chul Williams & Wilkins Co 2018 Medicine Vol.97 No.42
<P><B>Abstract</B></P><P>A multicenter Korean Prostate Cancer Database (K-CaP) has been established to provide information regarding Korean patients with prostate cancer (PCa). We used the K-CaP registry to investigate the value of age and comorbidity for predicting cancer-specific mortality (CSM) and other-cause mortality (OCM) according to risk grouping.</P><P>The K-CaP registry includes 2253 patients who underwent radical prostatectomy (RP) between May 2001 and April 2013 at 5 institutions. Preoperative clinicopathologic data were collected and stratified according to the National Comprehensive Cancer Network risk criteria. Survival was evaluated using Gray's modified log-rank test according to risk category, age (<70 years vs ≥70 years), and Charlson comorbidity index (CCI) (0 vs ≥1).</P><P>The median follow-up was 55.0 months (interquartile range: 42.0–70.0 months). Competing-risk regression analysis revealed that, independent of CCI, ≥70-year-old high-risk patients had significantly greater CSM than <70-year-old high-risk patients (<I>P</I> = .019). However, <70-year-old high-risk patients with a CCI of ≥1 had similar CSM relative to ≥70-year-old patients. Survival was not affected by age or CCI among low-risk or intermediate-risk patients. Multivariate analysis revealed that a CCI of ≥1 was independently associated with a higher risk of CSM (<I>P</I> = .003), while an age of ≥70 years was independently associated with a higher risk of OCM (<I>P</I> = .005).</P><P>Age and comorbidity were associated with survival after RP among patients with high-risk PCa, although these associations were not observed among low-risk or intermediate-risk patients. Therefore, older patients with high-risk diseases and greater comorbidity may require alternative multidisciplinary treatment.</P>
Seung-Hwan Yun,Young-Uk Park,Sun-Ran Cho,Jin-Won Jeong,Youn-Ho Shin,Changmann Yoon,Hyun-Na Koo,Gil-Hah Kim 한국응용곤충학회 2011 한국응용곤충학회 학술대회논문집 Vol.2011 No.05
The American serpentine leafminer fly, Liriomyza trifolii (Burgess), is one of the most destructive polyphagous pests world wide. In this study, we determined electron beam doses for inhibition of normal development of the L. trifolii and investigated the effect of electron beam irradiation on DNA damage and p53 stability. Eggs, larvae, pupae and adults were irradiated with increasing doses of electron beam irradiation (six levels ranges from 30 to 200 Gy). At 150 Gy, the number of adults that developed from irradiated eggs, larvae and pupae was lower than those of untreated control. Fecundity and egg hatchability decreased depending on the doses applied. Reciprocal crosses between irradiated and unirradiated flies demonstrated that males were more radiotolerant than females. Adult longevity was not affected in all stages. The levels of DNA damage in L. trifolii adults were evaluated using the alkaline comet assay. Our results indicate that electron beam irradiation increased levels of DNA damage in a dose-dependent manner. Moreover, low doses of electron beam irradiation led to the rapid appearance of p53 protein with in 6 h; however, it decreased after exposure to high doses (150 Gy and 200 Gy). These results suggest that electron beam irradiation induced not only abnormal development and reproduction but also p53 stability caused by DNA damage in L. trifolii. We conclude that a minimum dose of 150 Gy should be sufficient for sterilization of L. trifolii.
Seung Ju Lee,Jong Ung Yoon,Geun Ho Park,Hyun Kyung Kim,Gil-Hah Kim 한국응용곤충학회 2018 한국응용곤충학회 학술대회논문집 Vol.2018 No.04
The susceptibility of Dermanyssus gallinae adults, collected from poultry farms in 5 regions, to 11 acaricides was investigated. When bifenthrin and formic acid with pyridaben were diluted 100 times, bifenthrin showed 100% acaricidal activity; however, formic acid with pyridaben showed less than 20% acaricidal activity for poultry farms in 3 regions (Gyeongju, Chilgok, and Geumsan) except Yeoncheon and Anseong. Clothianidin, thiamethoxam, fenitrothion, and formic acid with pyridaben showed differences in acaricidal activity among regions. Therefore, farmers should concentrate during the selection of these acaricides. However, carbaryl, cartap hydrochloride, dichlorvos, and bifenthrin showed high activity against D. gallinae collected from poultry farms in five regions. To control D. gallinae effectively, the alternation of acaricides is necessary, and indiscriminate pesticide use should be avoided. Therefore, this study can serve as a basis for controlling D. gallinae.
Geun-Ho Park,Seung-Ju Lee,Dae-Hoon Jeong,Won-Jin Kang,Yejin Kyung,Jae-Seon Lee,Sun-Ran Cho,Hyun-Na Koo,Hyun-Kyung Kim,Gil-Hah Kim 한국응용곤충학회 2017 한국응용곤충학회 학술대회논문집 Vol.2017 No.10
The distribution of mosquitoes collected in Cheongju area in 2016 and 2017 were compared. The collection sites wereestablished from residential area, migratory bird sanctuary, and cattle feedlot using BL trap and BG trap. Culex pipienswere the most collected in residential area, and Aedes vexans were the most collected in migratory bird sanctuary andcattle feedlot in both years. BG trap was more collected than BL trap in residential area and migratory bird sanctuary.However, cattle feedlot was more collected in BL trap. A variety of mosquito species were collected from BG trap thanBL trap. However, the number of Anopheles sinensis collected in cattle feedlot showed significant differences betweenBL trap and BG trap. Based on the results of this study, it is considered that effective monitoring of mosquitoes mightbe done by using appropriate trap type according to the region
Acaricidal activity of 63 commercial pesticides agaisnt Haemaphysalis logicornis (Acari: Ixodidae)
Geun-Ho Park,Sung Il Kim,Sung Woo Cho,Seung-Ju Lee,Geon-Hui Lee,Sun-Ran Cho,Soeun Shin,Hyun-Na Koo,Hyun Kyung Kim,Gil-Hah Kim 한국응용곤충학회 2018 한국응용곤충학회 학술대회논문집 Vol.2018 No.10
Acaricidal activities of 63 commecial pesticides against the longhorned tick, H. logicornis were investigated. Twenty-two pesticides (4 cabamates, 5 organophophates, 9 pyrethroids, 1 octopamine receptor agonists, 1 diamides, and 1 unknown) against adults H. logicornis showed >80% mortalities after 72 h of treatment. The residual effect of 22 pesticides was investigated at 1, 2, 3, 7, and 10 day intervals on grass for H. logicornis adults and nymphs. Eight and twenty pesticides in H. logicornis adults and nymphs showed >80% acaricidal activity at 3 days after the treatment, respectively. 7 days after the treatment, H. logicornis adults showed <60% acaricidal activity in all pesticides, but 7 pesticides (benfuracarb, gamma cyhalothrin, cypermethrin, lammda cyhalothrin, fenvalerate, cyantraniliprole, fluxametamide) showed >80% acaricidal activity in nymphs. all pesticides exhibited <60% acaricidal activity after 10 days of treatment both adults and mymphs, except benfuracarb showed 96.7% mortality in H. logicornis nymph.
Lee Seung-Jun,Cho Kyoung Hwan,Kim Jong Cheol,Choo Ho Jin,Hwang Jeong-Yun,Cho Hyun Chin,Hah Young-Sool 한국응용생명화학회 2024 Applied Biological Chemistry (Appl Biol Chem) Vol.67 No.-
Obesity, a prevalent disease associated with numerous chronic conditions, including hyperlipidemia, hyperglycemia, diabetes, and metabolic syndrome, remains a major global health challenge. This study investigated the potential of green tea (GT), fermented tea (FT), and γ-aminobutyric acid (GABA) tea (GBT), which are rich in phytonutrients and polyphenols, for the management of obesity. Using a high-fat diet-induced obese mouse model (C57BL/6N), we explored the effect of these teas on various obesity-related parameters. The mice were categorized into five groups: normal diet with water, high-fat diet with water, and high-fat diet supplemented with GT, FT, or GBT. Over 13 weeks, we monitored body weight, perirenal and liver fat, adipocyte lipid accumulation, and key metabolic indicators, such as serum cholesterol, leptin, insulin, and fasting blood glucose. These teas contain beneficial phytochemicals such as GABA, theanine, and caffeine, and have demonstrated an enhanced antioxidant capacity, which increases the scavenging of free radicals and may reduce oxidative stress. The animal study indicated a decrease in feeding efficiency and significant reductions in body weight liver fat, epididymal fat, and perirenal fat, as well as in adipocyte lipid accumulation. Additionally, notable improvements were observed in metabolic health indicators, including reductions in serum cholesterol, leptin, insulin, and fasting blood glucose levels. Our findings revealed that GT, FT, or GBT significantly counteracted the negative effects of a high-fat diet, suggesting their potential in combating obesity and related metabolic disorders.
Youn Ho Shin,Seung Hwan Yun,Young-Uk Park,Jeong-Jin An,Yong-Man Yu,Gil-Hah Kim 한국응용곤충학회 2011 한국응용곤충학회 학술대회논문집 Vol.2011 No.10
From April 2010 to the present, seasonal occurrence of Riptortus pedestris was investigated. Five locations for population density and migration route tracking were the same as last year (two sites of Mt. Yangseong, Jujung-dong, O-Chang, and the campus of Chungbuk National University(CBNU)). In Mt. Yangseong, separated the farmland (80m) and forest (200 and 300m) by altitude, population density in 2010 was showed high density at mid-June, mid-Aug., and late-Oct., but population density in 2011 was showed high density at late-April, late-July and mid-Aug. In O-Chang and Jujung-dong, population density in 2010 was captured the adult from June to Aug. in the farmland, and from Sept. to Nov. in the forest. Total captured number of R. pedestris were high in farmland than forest. In campus of CBNU, the adult was captured from mid-Jul. to late-Aug. It showed the difference in the population density by its environmental conditions. Attraction effect of pheromone lure trap with soybeans were good than that of pheromone lure trap only. To track the migration of R. pedestris, we painted the fluorescent paint with different color. Being painted 500 R. pedestris were released and recaptured 10 and 20 days after release. Among released 500 R. pedestris at asl 300m on Yangseong site A and B in 25 Apr. were recaptured one at 300 and 80 m at site A, and site B was recaptured one marked R. pedestris adult at 200 m. In 25 May, release at 200 m in site A was recaptured only 80 m with 2 and site B was recaptured 200m with 8 and 80m with 1. Released in 17 Jul. at 80 m, marked R. pedestris adults were recaptured only 80 m with 5 and 2, respectively. It means that R. pedestris adults seem to migrate from the forest to the farmland in this season, but the data from Aug. to Oct. in 2010 was different.