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1KW급 BLDC 모터 기반의 수중추진체 개발에 관한 연구
장하용(Ha-Lyong Jang),소명옥(Myung-Ok So),하윤수(Yun-Soo Ha),최형식(Hyeung-Sik Choi),강신영(Sin-Young Kang),박한일(Han-Il Park) 대한조선학회 2011 대한조선학회 학술대회자료집 Vol.2011 No.6
This paper is about the development of the 1KW class underwater thrusting system driven by a brushless DC motor (BLDC) for underwater robots. A design of the structure such as the structure analysis on the thrusting system using FEM and the design of the propeller using the fluid analysis has been performed. Also, a new structure such as decoupling and non-gear structure has been explained. The performance test of the designed and developed thrusting system in water and in air was undertaken and its results were compared with an existing product with high performance.
( Jin Ho Kim ),( Nam Gyoung Ha ),( Seon Hwa Lee ),( Dae-lyong Ha ),( Kyung Duck Park ),( Yong Hyun Jang ),( Seok-jong Lee ),( Weon Ju Lee ) 한국피부장벽학회 2023 한국피부장벽학회지 Vol.25 No.2
Background: Hyaluronic acid (HA) is mainly used to treat xerosis. It also exerts wound-healing, moisturizing, and antiaging effects. Although HA is considered an effective and safe ingredient in cosmetics, there is a constant demand for a more economical and effective formulation. Objective: This study aimed to evaluate the safety and efficacy of a novel hydrogel-based moisturizer containing HA, produced solely through irradiation without using cross-linking agents. Methods: We confirmed both safety and efficacy of prototype moisturizer (Type A) and product with enhanced moisturizing (Type B), sequentially. Safety studies for each moisturizer enrolled 30 participants with healthy skin to perform patch and photopatch tests while recording adverse events. For the efficacy studies of each moisturizer, 30 participants with xerosis were compared before and after using the novel hydrogel, evaluating the cutaneous barrier function, xerosis severity scale (XSS) score, participant’s satisfaction, and Investigator’s Global Assessment (IGA). Furthermore, the efficacy of the novel hydrogel-based moisturizer was evaluated by comparing it with a conventional moisturizer, Physiogel<sup>®</sup>, in another 30 participants with xerosis. Results: In the safety study, no serious adverse events were observed in both Type A and B. In the efficacy study of type A and B, skin hydration and skin surface lipid increased (p < 0.05) whereas the XSS scores decreased (p < 0.05) with time. In the comparative efficacy study with Physiogel<sup>®</sup>, skin hydration increased whereas the XSS scores decreased (p < 0.05) over time in both groups. Furthermore, IGA improved in 100% of participants in both groups. Also, 100% and 93% of participants were satisfied with the novel hydrogel-based moisturizer and Physiogel<sup>®</sup>, respectively. Conclusion: The novel hydrogel-based moisturizer proved to be safe and effective for xerosis, showing comparable results to the conventional moisturizer.
1-(2-pyridylazo)-2-naphthol을 킬레이트제로 사용한 Co(Ⅱ)의 염석추출법적 정량
서무룡,하광수,장미경 경상대학교 환경보전연구소 1996 環境保全硏究所報 Vol.4 No.1
As a part of analytical application of 1-(2-pyridylazo)-2-naphthol(PAN), the extraction method with salting-out technique was applied to the determination of cobalt(Ⅱ) ion in aqueous solution. After cobalt(Ⅱ) was extracted from the buffered aqueous solution into acetonitrile layer as a Co(Ⅱ)-PAN chelate by salting-out technique, the visible absorption spectrum was recorded. In this experiment, ammonium sulfate was used as a salting-out reagent. The effects of amount of ammonium sulfate and extracting reagent, PAN on the extractability, the relationship between pH of the aqueous phase and extractability of Co(Ⅱ)-PAN chelate, and the calibration curves for the determination of Co(Ⅱ) by spectrophotometry and differential pulse polarograph have been evaluated. The effects of diverse ion on the determination of Co(Ⅱ) by these methods have also been investigated.
( Nam Gyoung Ha ),( Seon Hwa Lee ),( Dae-lyong Ha ),( Kyung Duck Park ),( Yong Hyun Jang ),( Weon Ju Lee ),( Seok-jong Lee ),( Jun Young Kim ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1
Background: Although cryotherapy is widely used as a treatment for actinic keratosis (AK), the manual control of cryotherapy makes it difficult to perform with a consistent intensity and to predict adverse events (AEs). For easy and accurate control of cryotherapy, temperature- and time-controlling cryotherapy device (TTCCD) was recently developed. Objectives: This study aims to evaluate the efficacy and safety of TTCCD to treat a mild facial AK. Methods: Patients with clinical diagnosis of mild AK on face were treated with TTCCD at -20℃ for 20 s in a single freeze-thaw cycle. Until achieving complete response, treatment was repeated every 4 weeks. At 4 weeks after the 1st treatment (4WFT), cure rate (CR) and AEs were assessed. At 12 weeks after the last treatment (12WLT), CR, recurrence rate, AEs and cosmetic outcomes were assessed. Results: Twenty-one patients with 34 lesions were enrolled and treated with an average of 1.15±0.5 sessions. At 4WFT and 12WLT, CR was 91.2 % and 97.1 %, respectively. There was no serious AEs and only erythema and hypopigmentation were observed. At 4WFT and 12WLT, rate of erythema had decreased (from 32.4 % to 5.9 %) whereas rate of hypopigmentation had remained (from 20.6 % to 23.5 %). Cosmetic outcome was good to excellent in 90 % of patients’ response and 100 % of investigators’ assessment. Conclusion: A TTCCD is an effective and safe treatment modality for mild facial AK resulting in good cosmesis.
( Nam Gyoung Ha ),( Seon Hwa Lee ),( Dae-lyong Ha ),( Kyung Duck Park ),( Yong Hyun Jang ),( Weon Ju Lee ),( Seok-jong Lee ),( Jun Young Kim ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.-
Background: Although cryotherapy is widely used as a treatment for actinic keratosis (AK), the manual control of cryotherapy makes it difficult to perform with a consistent intensity and to predict adverse events (AEs). For easy and accurate control of cryotherapy, temperature- and time-controlling cryotherapy device (TTCCD) was recently developed. Objectives: This study aims to evaluate the efficacy and safety of TTCCD to treat a mild facial AK. Methods: Patients with clinical diagnosis of mild AK on face were treated with TTCCD at -20℃ for 20 s in a single freeze-thaw cycle. Until achieving complete response, treatment was repeated every 4 weeks. At 4 weeks after the 1st treatment (4WFT), cure rate (CR) and AEs were assessed. At 12 weeks after the last treatment (12WLT), CR, recurrence rate, AEs and cosmetic outcomes were assessed. Results: Twenty-one patients with 34 lesions were enrolled and treated with an average of 1.15±0.5 sessions. At 4WFT and 12WLT, CR was 91.2 % and 97.1 %, respectively. There was no serious AEs and only erythema and hypopigmentation were observed. At 4WFT and 12WLT, rate of erythema had decreased (from 32.4 % to 5.9 %) whereas rate of hypopigmentation had remained (from 20.6 % to 23.5 %). Cosmetic outcome was good to excellent in 90 % of patients’ response and 100 % of investigators’ assessment. Conclusion: A TTCCD is an effective and safe treatment modality for mild facial AK resulting in good cosmesis.
( Gi Ung Ha ),( Jin Seon Bang ),( Dae-lyong Ha ),( Jun Young Kim ),( Kyung Duck Park ),( Yong Hyun Jang ),( Weon Ju Lee ),( Seok-jong Lee ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.-
Background: Surgical procedures such as wide local excision (WLE) and Mohs micrographic surgery (MMS) are the only treatment of choice to eradicate extramammary Paget’s disease (EMPD). MMS is applauded as successful treatment lately, however, there were few recent studies analyzing the efficacy of WLE of EMPD in terms of survival rate following excision in South Korea. Objectives: This study aims to analyze the EMPD-specific survival rates (ESS), overall survival (OS) and recurrence rate (RR) of patients with EMPD in South Korea, focused on WLE. Methods: We retrospectively reviewed the medical records of patients with EMPD from 1993 to 2020 at Kyungpook National University Hospital. We calculated the ESS, OS of EMPD patients and RR after WLE. Results: Total 95 patients whose medical records including surgical and survival data are observable were included, with a mean age of 67.8 years. The 5-year ESS/OSs were 91.8℅/79.3℅ and 10-year ESS/OSs 81.6℅/64.7℅ and there was no difference between sex. Seventy-five patients underwent WLE by either dermatologists (64℅), gynecologists (25℅), or plastic surgeons (11℅). The RR was 16 % in patients who treated with WLE: 7 local recurrence, 2 regional and 3 distant metastases, with mean 39.2 months of recurrence-free interval. Conclusion: From the point of view of ESS, OS and RR, as a surgical treatment by WLE also has fair enough curative effacement for EMPD, comparable to MMS.
( Nam Gyoung Ha ),( Seon Hwa Lee ),( Eun Hye Lee ),( Dae-lyong Ha ),( Kyung Duck Park ),( Yong Hyun Jang ),( Weon Ju Lee ),( Seok-jong Lee ),( Jun Young Kim ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.72 No.2
Skin color change to dark reddish brown (DRB) of whole body in ordinary Koreans is rare and often occurred by severe liver disease, side effects of medications, etc. However, DRB skin by an infection is not common. A newborn with early congenital syphilis (ECS) and cytomegalovirus infection was referred to dermatology. He was premature infant delivered at gestational age 27 weeks with a birth weight of 840 g. Although his parents were Koreans, he showed generalized DRB skin (Fitzpatrick’s skin phototype VI) and multiple edematous vesiculobullous lesions with desquamation and serous discharge on body folds and weight-bearing area. He presented distended abdomen and, hyperbilirubinemia, hepatomegaly, thrombocytopenia and renal failure were also observed on the examination. Despite of intensive treatment with ampicillin, meropenem and ganciclovir, he eventually expired 24 days after birth. Although ECS is one of well-known congenital infections, nowadays dermatologists have a rare chance to experience ECS in practice. Cutaneous feature of ECS is typically a copper-red maculopapular skin eruption on palms and soles. However, he showed generalized DRB skin and hyperbilirubinemia, hepatomegaly, thrombocytopenia which imply severe hepatic dysfunction. Based on these findings, the DRB skin is thought to be caused by severe jaundice. We report a fatal case of ECS presenting with multiple vesiculobullous eruption and generalized DRB skin.
Diagnostic Process of Subcorneal Pustular Dermatosis: A Case Report
( Gi Ung Ha ),( Seok-jong Lee ),( Weon Ju Lee ),( Yong Hyun Jang ),( Jun Young Kim ),( Dae-lyong Ha ),( Kyung Duck Park ) 대한피부과학회 2024 대한피부과학회지 Vol.62 No.3
A 54-year-old man presented to our outpatient clinic with generalized pruritic millet-sized vesicles, pustules, and crusts on the whole body over the past 10 years, which were more dominant in the lower extremities. Due to the difficulty in diagnosis, a series of histopathologic examinations were conducted during the treatment course, and the findings were similar: subcorneal pustules with neutrophils, superficial perivascular and dermal infiltration of lymphocytes, neutrophils, and eosinophils, with no sign of acantholysis. The patient was treated with cyclosporine, prednisolone, doxycycline, colchicine, sulfasalazine, and acitretin; however, his condition did not improve. After showing a dramatic improvement with dapsone, he was finally diagnosed with subcorneal pustular dermatosis (SPD). Various medications commonly used in inflammatory and immunobullous skin diseases were tried but failed to improve the condition; the patient showed a dramatic response only to dapsone. Due to its rarity, careful attention and repeated biopsies are required for diagnosing SPD. (Korean J Dermatol 2024;62(3):169∼171)