정하중열싸이클법을 이용한 Ti-Ni 계 형상기억합금의 형상회복응력 연구

하광수,남태현,노정필 대한금속재료학회(대한금속학회) 1996 대한금속·재료학회지 Vol.34 No.9

Shape recovery stress of Ti-50.2Ni and Ti-(50-X)Ni-XCu(at%)(X=5-30) shape memory alloys has been measured by means of thermal cycling tests under constant load. In each alloy, the shape recovery stress increased with increasing applied stress up to the critical stress for slip deformation, above which it decreased with increasing applied stress. This was due to decrease in recoverable elongation by the slip deformation. The critical stress for slip deformation depended on Cu-content. With respect to the maximum shape recovery stress, for the alloys whose Cu-content was less than 5at% and more than 15at%, it decreased with increasing Cu-content. For the alloys whose Cu-content was between 5at% and 15at%, however, it increased with increasing Cu-content. Cu-content dependence of the maximum recovery force did not correspond to that of recoverable elongation. Thermal cycling test under costant load method was effective to measure a heating temperature dependence of the shape recovery stress.

主題公園 訪問者의 滿足과 訪問後 行動意圖의 決定要因

하광수,한범수 한국관광학회 2001 관광학연구 Vol.25 No.1

1,5,9,13-Tetrathiacyclohexadecane 수식전극을 사용한 Ag(I)의 전기화학적 정량

하광수,장미경,서무룡,Ha, Kwang Soo,Jang, Mi-Kyeong,Seo, Moo Lyong 한국분석과학회 1997 분석과학 Vol.10 No.3

[16]-ane-$S_4$/탄소분말 함량비를 50%로 하여 nujol oil과 혼합하여 수식전극을 제조하였다. $5.0{\times}10^{-4}M$ $Ag^+$를 포함하는 pH 4.5인 아세트 완충용액에 수식전극을 담가 $Ag^+$를 전극 표면에 흡착시켰다. 이 때 흡착시간을 15분으로 하고 전해환원시키는 시간은 -0.3V vs S.C.E에서 2분으로 하였다. 또한 0.1M $HNO_3$ 용액으로 전극을 활성화시켰으며 한번 활성화한 전극은 10회까지 사용이 가능하였다. 최적 분석조건에서 미분펄스 전압전류법으로 $5.0{\times}10^{-7}{\sim}1.5{\times}10^{-6}M$ 사이의 농도 범위에서 정량해 보았을 때 직선성이 잘 성립하였으며, 검출한계는 $2.0{\times}10^{-7}M$이었다. 대부분의 금속들은 방해를 주지 않았으나, Cu(II)은 방해를 나타내었다. Chemically modified electrodes(CMEs) for Ag(I) were constructed by incoporating 1,5,9,13-tetrathiacyclohexadecane([16]-ane-$S_4$) with a conventional carbon-paste mixture composed of graphite powder and nujol oil. Ag(I) ion was chemically deposited onto the surface of the modified electrode with [16]-ane-$S_4$ by immersion of the electrode in the acetate buffer solution(pH=4.5) containing $5.0{\times}10^{-4}M$ Ag(I) ion. And then the electrode deposited with Ag(I) was reduced at -0.3V vs. S.C.E. Well-defined stripping voltammetric peaks could be obtained by scanning the potential to the positive direction. The CME surface was regenerated with exposure to 0.1M $HNO_3$ solution and was reused for the determination of Ag(I) ion. When deposition/measurement/regeneration cycles were 10 times, the response could be reproduced with relative standard deviation of 6.08%. In case of differential pulse stripping voltammetry, the calibration curve for Ag(I) was linear over the range of $5.0{\times}10^{-7}{\sim}1.5{\times}10^{-6}M$. And the detection limit was $2.0{\times}10^{-7}M$. Various ions such as Cd(II), Ni(II), Pb(II), Zn(II), Mn(II), Mg(II), EDTA, and oxalate(II) did not influence the determination of Ag(I) ion, except Cu(II) ion.

Complete genome sequence of Bacillus velezensis SRCM102755, a high menaquinone-7 producer, isolated from Doenjang

하광수,임수아,신수진,류민지,김진원,정성엽,정도연 한국미생물학회 2020 미생물학회지 Vol.56 No.1

Bacillus velezensis SRCM102755, isolated from Doenjang was screened as a starter for Cheonggukjang containing high menaquinone-7 (MK-7) production. Here, we report the complete genome sequence of B. velezensis SRCM102755. The complete genome was sequenced by Pacific Biosciences (PacBio) singlemolecule real-time (SMRT) RS II platform. The genome consists of a single, circular chromosome of 4,044,843 base pairs with a G + C content of 46.34%, and included 3,856 protein coding genes and 113 RNA genes (27 rRNA genes, 86 tRNA genes). The genome was identified to contain at least of nine genes involved in MK-7 biosynthesis.

2002 년도 제 27 회 보건학종합학술대회 : PCR 과 RAPD ( Random Amplification Polymorphic DNA ) 분석을 통하여 목장에서 분리된 Staphylococcus aureus 의 특성

하광수,박선자,정종화,정덕화 대한보건협회 2002 대한보건협회 보건종합학술대회 Vol.- No.-

급성 골수성 백혈병 10세 환아의 한방적 처치에 대한 증례보고

하광수,송인선,신지나,이정림,Ha, Kwang-Su,Song, In-Sun,Shin, Ji-Na,Lee, Jeong-Lim 대한한방소아과학회 2004 대한한방소아과학회지 Vol.18 No.2

저자는 급성 골수성 백혈병으로 진단받은 환아의 범혈구감소증으로 인한 출혈(出血)소견과 전신자반증(全身紫班症), 정신의식계통의 혼돈(混沌)과 극도의 허손(虛損)상태를 경험하고 이를 한방적으로 접근하여 짧은 기간이었으나마 호전도를 경험하였기에 보고하는 바이다. 백혈병은 아직까지는 한방으로 완치(完治)라는 것이 어려운 분야이지만, 일차적으로 관해 유도법을 도입하기전이나 관해 후의 허손(虛損)으로 환자의 체력이 됫받침되지 못할때 충분히 양방과 협진하여 그 효과를 입증할수 있다고 생각된다. 아직까지 한방분야에서 백혈병 등의 혈액암에 있어서는 그 문헌적인 연구는 미흡하나마 존재하지만, 임상적인 연구나 치료방법적인 면으로는 보고된 바가 부족하며 이 논문을 계기로 다양한 임상연구가 진행되었으면 하는 바람이다. Objective : The purpose of this study is to demonstrate the therapeutic effect of oriental treatment on Acute Myelogenous Leukemia. Methods : The patient was treated by Acupuncture, Indirect Moxibustion, Herb Medicine (Seogakjihwangtang-gamibang), and had significant improvement in the Acute Myelogenous Leukemia. Results : 1. Acute Leukemia is one of the most common malignant neoplasm of pediatrics, and is chracterised by anemia, infections, bleeding, debility, paleness, fever, anorexia, lymphoadenia, hepatomegaly, splenomegaly, etc. 2. The management of Acute Myelogenous Leukemia consists of the challenge of optimizing chance for prolonged remission and cure, while minimizing the toxicity to the patients. Therefore oriental medical treatment may be useful for this. 3. We experienced a case of the 10-year-old male patient with Acute Myelogenous Leukemia, after oriental medical treatment his chief symptoms(anemia, bleeding, purpura, debility, paleness, fever, anorexia, insomnia, etc)and general condition were improved. Conclusion : A 10-year-old male patient with Acute Myelogenous Leukemia, after oriental medical treatment his chief symptoms and general condition were improved. This oriental medical treatment may be possible or effective in Acute Myelogenous Leukemia. The more clinical study about oriental medical treatment on Acute Myelogenous Leukemia will be needed.

Cerebellar Atrophy로 인해 유발된 Spinocerebellar Ataria 환아(患兒) 1례(例) 보고(報告)

하광수,김선미,하수연,송인선,이정림,Ha, Kwang-Su,Kim, Sun-Mi,Ha, Su-Yun,Song, In-Sun,Lee, Jeong-Lim 대한한방소아과학회 2005 대한한방소아과학회지 Vol.19 No.2

저자는 Brain MRI 상 Cerebellar atrophy로 인한 척수소뇌성 운동실조증으로 진단받은 6세 환아의 Ataxia, Dysarthria, 두부진전증(頭部振顫症), 안진(眼振) 등에 대해 한방적 치료 후 호전도가 있었기에 이에 증례보고(證例報告)하는 바이다. 특히 두진(頭振), 안진(眼振)과 같은 진전(振顫)질환과 실조증에 대하여 두침(頭鍼)시술이 유효성이 컸으며, 오지(五遲) 오연증(五軟證)에 대하여서 간(肝), 신정격(腎正格)과 육미지황탕(六味地黃湯)의 장기 투여가 효과가 있었다. 일반적인 SCA, ADCA가 청, 장년기 이후에 발생하고 유전적인 경향이 큰 것에 반해 재태(在胎)시 큰 이상없이 생후 특발적으로 발생한 척수 소뇌성 운동실조에 대하여서는 한방적으로 증례보고(證例報告) 된 바가 드문 실정으로 유, 소아의 이러한 질환에 대한 진일보된 연구과 함께 평가척도나 치료방법적인 면에서의 고찰(考察)이 더욱 필요하리라 사료된다. Objective : The autosomal dominent cerebellar ataxia(ADCA) is an unusal familial herediatary disorder that has been called olivopontoerebellar atrophy. Recently ADCA referred to as spinocerebellar ataxia(SCA) by molecular genetic characteristics. The purpose of this study is to focus on the improvement of clinical symptoms in SCA patient by oriental medical treatment. Materials & Methods : We experienced a case of the 6-year-old female patient with SCA and the MRI showed atrophy of cerebellum. The patient's chief symptoms come within the purview of five kinds of retardation and five kinds of flaccidity. We treated her with herb medicine (Yukmijihwang-tang gamibang), acupuncture, scalp acupuncture. After we measured the progress of general condition by MBI(Modified Bathel Index). Results : After oriental medical treatment, chief symptoms (ataxia, weakness of low extremities, dysarthria, etc.) and general condition were improved. Conclusion : We suggest that oriental medical therapy is effective to the possibility of treatment on SCA, but more clinical study and observation should be needed.

수술 후 발생한 뇌졸중으로 인한 연하장애 환아 증례 1례

하광수,김선미,나효석,최윤희,하수연,김하얀,송인선,Ha, Kwang-Su,Kim, Sun-Mi,Na, Hyo-Sock,Choi, Yun-Hui,Ha, Su-Yun,Kim, Ha-Yan,Song, In-Sun 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.3

Objectives : Cerebrovascular disease in children is more common than once recognized and the etiology. In stroke patient, dysphagia is a common. Dysphagia often affects the rehabilitation of stroke patients by increasing the risk of aspiration pneumonia and malnutrition. This is the clinical report about 1 case of patient with dysphagia who had a stroke developed after operation. Methods : The herb medicine, moxibustion and acupuncture therapies were applied for treating this patient's chief symptom. Results : This patient's dysphagia was improved by oriental medical therapy. Conclusions : The result suggests that the herb medicine and acupuncture therapies is efficacious against dysphagia associated with stroke. We though that more studies about the Oriental medical treatment on dysphagia associated with stroke are needed.

디지털과 아날로그 콘텐츠 융합을 통한 어린이 그림책 만들기 활동방법

하광수 한국콘텐츠학회 2020 한국콘텐츠학회논문지 Vol.20 No.2

Advancements in digital technology have caused significant changes to the tradition of creative educational activities. Such an with digital technology is prone to an error where digital technology itself becomes the goal, ignoring educational efficacy grounded on improved user experience and immersion. Previously, picture book-making activities for children allow them to actively participate in the process of book-making, and is often employed to instill reading habits as well as nurture linguistic abilities. Aside from such picture book-making activities, diverse efforts are being made for innovation in educational pedagogy through digital technology. However, as the goal of children’s picture book-making activities is realizing creative education through expressions in language and pictures, digital technology should be considered in the viewpoint of fusion, not as a simple replacement to the traditional tools employed in children’s picture book-making activities. This study examines previous researches related to children’s picture book-making activities to propose contents and methodology allowing effective immersion by fusing digital technology based on a physical environment, from the viewpoint of fusion and integration. Expect this study will become a fundamental data in visualizing a practical integration of digital technology in future creative education. 디지털기술의 발달은 창의 교육 활동의 전통에 큰 변화를 주고 있다. 그러나 디지털 중심의 맹목적 접근은 사용자 경험(UX)의 증대와 몰입을 기반으로 한 교육 효과를 외면한 채 디지털기술 그 자체가 목적이 되는 오류를 범하기 쉬울 것이다. 그간 교육현장에서 어린이 그림책 만들기 활동은 어린이 스스로 책을 만드는 과정에 적극적으로 참여함으로써 책 읽는 습관과 함께 언어능력을 발달시키는 데 도움을 주는 활동으로 즐겨 사용되었다. 이런 어린이 그림책 만들기 활동을 통한 교육에도 디지털기술을 이용한 교육방법의 변화와 혁신이 다양하게 시도되고 있다. 그러나 어린이 그림책 만들기 활동의 목적은 언어와 그림 표현을 통해 창의적 교육을 실현하기 위한 것으로, 디지털기술은 전통적 방식의 어린이 그림책 만들기 활동을 위한 도구의 단순한 대체가 아닌 융합의 관점에서 검토되어야 할 것이다. 본 연구에서는 어린이 그림책 만들기 활동과 관련한 그간의 연구를 분석하고, 이를 기반으로 융합적이며 통합적인 관점에서 효과적 몰입을 끌어낼 수 있는 어린이 그림책 만들기 콘텐츠와 활동방법을 제안하였다. 본 연구를 통해 기존 교육방식과 디지털기술을 효과적으로 융합하는 사용자 경험을 제안함으로써 앞으로의 창의 교육 현장에서 디지털기술의 실질적 융합을 가시화시킬 수 있게 되는 기초자료가 될 수 있을 것으로 기대된다.

가공열처리한 Ti-Ni-Cu 형상기억합금의 형상회복응력

하광수,남태현,조규봉,허신구 대한금속재료학회(대한금속학회) 1997 대한금속·재료학회지 Vol.35 No.3

Shape recovery stress of thermo-mechanically treated Ti-Ni and Ti-Ni-Cu shape memory alloys has been investigated by means of thermal cycling test under constant load and also and effect of thermo-mechanical treatment on transformation behaviour and transformation temperatures has been examined by means of electrical resistivity measurements, differential scanning calorimetry and X-ray diffraction. Transformation behaviour was not changed by thermo-mechanical treatments in Ti-Ni-Cu alloys, while it changed from B2(cubic)-B19'(monoclinic) to B2-R(rhombohedral)-B19' in the Ti-Ni alloy. Martensitic transformation start temperature increased silghtly by thermo-mechanical treatments in Ti-Ni-Cu alloys, while it decreased largely in the Ti-Ni alloy. Shape recovery stress of Ti-Ni-Cu alloys was larger than that of the Ti-Ni alloy. This was attributed to the fact that the maximum recoverable elongation of Ti-Ni-Cu alloys was larger than that of the Ti-Ni alloy. And also shape recovery stress depended of Cu-content. It increased from 290MPa to 400MPa with increasing Cu-content up to 5at%, and then decreased from 400MPa to 375MPa with increasing Cu-content from 5at% to 10at%.