REAL TIME DETECTION AND CLASSIFICATION OF ARROW MARKINGS IN URBAN STREETS

Frank Philipp,Sven Schumacher,Hadj Hamma Tadjine,Raúl Rojas 한국자동차공학회 2018 International journal of automotive technology Vol.19 No.2

For highly automated driving in urban regions it is essential to know the precise position of the car. Furthermore it is important to understand the surrounding context in complex situations, e.g. multilane crossings and turn lanes. To understand those situations there is not only the task to detect the lane border, but to detect the painted information inside the lane. The paper is facing and evaluating two methods to classify this additional lane information. Therefore the images from five cameras mounted around the car are used. Four of them with fisheye lenses. The methods have in common, that the input images are transformed into a bird view projection. First introduced method is to extract contours from the transformed images and collect geometrical features and Fourier coefficients. The second introduced way, is to calculate histograms of oriented gradients and use it as input for the classification step. Both classification approaches are implemented and evaluated as multiclass and single class detectors for each arrow type. Furthermore, the classification results from a support vector machine and random forest were faced for this classification problem. The results from the multiclass detectors are evaluated and presented in form of confusion matrices. With the introduced approaches a high detection confidence could be achieved, proofed with validation datasets and in practical use.

Arrival at the Caspian Coast: Migration, Informality and Urban Transformation in Sumqayit, Azerbaijan

( Philipp Frank Jäger ) 계명대학교 실크로드중앙아시아연구원 2020 Acta Via Serica Vol.5 No.2

The city of Sumqayit in Azerbaijan was famous in the USSR for its chemical plants, which supplied the whole country with plastics, detergents, and fertilizers. While production increased in the post- WWII period, young people from remote Caucasian villages were attracted as workers to the industrial settlement on the shore of the Caspian Sea and worked together with specialists from all over the USSR. Migration did not stop when the USSR collapsed. To the contrary, mobility increased as Azerbaijani refugees from Armenia and IDPs from Karabakh fled to Sumqayit, which grew to become the second-largest city of Azerbaijan. Although a generation has passed since the ceasefire, IDPs still are separately administered. In the last 20 years, more and more internal migrants have chosen the Greater Baku Region as their destination, mostly finding jobs in the informal labor market. In the post-independence transformative period, informal housing has offered migrants a place to stay in the city. Sumqayit can be regarded as an arrival city, an established urban platform for migrants who prefer internal over transnational migration.

Advanced PM Processes for Medical Technologies

Petzoldt, Frank,Friederici, Vera,Imgrund, Philipp,Aumund-Kopp, Claus The Korean Powder Metallurgy Institute 2014 한국분말재료학회지 (KPMI) Vol.21 No.1

Medical technologies are gaining in importance because of scientific and technical progress in medicine and the increasing average lifetime of people. This has opened up a huge market for medical devices, where complex-shaped metallic parts made from biocompatible materials are in great demand. Today many of these components are already being manufactured by powder metallurgy technologies. This includes mass production of standard products and also customized components. In this paper some aspects related to metal injection molding of Ti and its alloys as well as modifications of microstructure and surface finish were discussed. The process chain of additive manufacturing (AM) was described and the current state of the art of AM processes like Selective Laser Melting and electron beam melting for medical applications was presented.

Intravesical Bacillus Calmette-Guérin versus mitomycin C for Ta and T1 bladder cancer: Abridged summary of the Cochrane Review

Stefanie Schmidt,Frank Kunath,Bernadette Coles,Desiree Louise Draeger,Laura-Maria Krabbe,Rick Dersch,Samuel Kilian,Katrin Jensen,Philipp Dahm,Joerg J Meerpohl 대한비뇨의학회 2020 Investigative and Clinical Urology Vol.61 No.4

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Transscleral LED illumination pen

Christian Lingenfelder,Frank Koch,Philipp Koelbl,Pia Klante,Martin Hessling 대한의용생체공학회 2017 Biomedical Engineering Letters (BMEL) Vol.7 No.4

Existing light sources for intraocular illuminationare often bulky and expensive and pose a risk for thepatient, because light guides are inserted in the eye throughincisions and if the tip of these light guides get too close tothe retina, the retina can be damaged photochemicallywithin minutes or even seconds. Therefore a new, safe andsimple device for intraocular illumination is developed andevaluated for its thermal and photochemical risks to thepatient. It consists of a white LED which is integrated intoa pen like holder. This device is pressed against the scleraby the physician who seeks for illumination during surgeryor for diagnostic purposes. The LED light is transmittedthrough the sclera without the need for an incision. Consideringthe relevant standards, the device poses no harm tothe patient, and in tests with the authors’ own eyes a sufficientintraocular illumination is reached. The proposeddevice is quite simple but easy to handle and very gentlefor the patient.

POTENTIAL APPLICATIONS FOR NUCLEAR ENERGY BESIDES ELECTRICITY GENERATION: A GLOBAL PERSPECTIVE

Gauthier, Jean-Claude,Ballot, Bernard,Lebrun, Jean-Philippe,Lecomte, Michel,Hittner, Dominique,Carre, Frank Korean Nuclear Society 2007 Nuclear Engineering and Technology Vol.39 No.1

Energy supply is increasingly showing up as a major issue for electricity supply, transportation, settlement, and process heat industrial supply including hydrogen production. Nuclear power is part of the solution. For electricity supply, as exemplified in Finland and France, the EPR brings an immediate answer; HTR could bring another solution in some specific cases. For other supply, mostly heat, the HTR brings a solution inaccessible to conventional nuclear power plants for very high or even high temperature. As fossil fuels costs increase and efforts to avoid generation of Greenhouse gases are implemented, a market for nuclear generated process heat will be developed. Following active developments in the 80's, HTR have been put on the back burner up to 5 years ago. Light water reactors are widely dominating the nuclear production field today. However, interest in the HTR technology was renewed in the past few years. Several commercial projects are actively promoted, most of them aiming at electricity production. ANTARES is today AREVA's response to the cogeneration market. It distinguishes itself from other concepts with its indirect cycle design powering a combined cycle power plant. Several reasons support this design choice, one of the most important of which is the design flexibility to adapt readily to combined heat and power applications. From the start, AREVA made the choice of such flexibility with the belief that the HTR market is not so much in competition with LWR in the sole electricity market but in the specific added value market of cogeneration and process heat. In view of the volatility of the costs of fossil fuels, AREVA's choice brings to the large industrial heat applications the fuel cost predictability of nuclear fuel with the efficiency of a high temperature heat source tree of Greenhouse gases emissions. The ANTARES module produces 600 MWth which can be split into the required process heat, the remaining power drives an adapted prorated electric plant. Depending on the process heat temperature and power needs, up to 80% of the nuclear heat is converted into useful power. An important feature of the design is the standardization of the heat source, as independent as possible of the process heat application. This should expedite licensing. The essential conditions for success include: ${\bullet}$ Timely adapted licensing process and regulations, codes and standards for such application and design ${\bullet}$ An industry oriented R&D program to meet the technological challenges making the best use of the international collaboration. Gen IV could be the vector ${\bullet}$ Identification of an end user(or a consortium of) willing to fund a FOAK

Bright Light Therapy in the Morning or at Mid-Day in the Treatment of Non-Seasonal Bipolar Depressive Episodes (LuBi): Study Protocol for a Dose Research Phase I / II Trial

Pierre Alexis Geoffroy,El Mountacer Billah El Abbassi,Julia Maruani,Bruno Etain,Michel Lejoyeux,Ali Amad,Philippe Courtet,Caroline Dubertret,Philip Gorwood,Guillaume Vaiva,Frank Bellivier,Sylvie Chevr 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.12

Objective This study protocol aims to determine, using a rigorous approach in patients with bipolar disorder (BD) and non-seasonal major depressive episode (MDE), the characteristics of bright light therapy (BLT) administration (duration, escalation, morning and mid-day exposures) depending on the tolerance (hypomanic symptoms). Methods Patients with BD I or II and treated by a mood stabilizer are eligible. After 1 week of placebo, patients are randomized between either morning or mid-day exposure for 10 weeks of active BLT with glasses using a dose escalation at 7.5, 10, 15, 30 and 45 minutes/ day. A further follow-up visit is planned 6 months after inclusion. Patients will be included by cohorts of 3, with at least 3 days of delay between them, and 1 week between cohorts. If none meet a dose limiting toxicity (DLT; i.e hypomanic symptoms), the initiation dose of the next cohort will be increased. If one patient meet a DLT, an additionnal cohort will start at the same dose. If 2 or 3 patients meet a DLT, from the same cohort or from two cohorts at the same dose initiation, the maximum tolerated dose is defined. This dose escalation will also take into account DLTs observed during the intra-subject escalation on previous cohorts, with a “Target Ceiling Dose” defined if 2 DLTs occured at a dose. Discussion Using an innovative and more ergonomic device in the form of glasses, this study aims to better codify the use of BLT in BD to ensure a good initiation and tolerance.

Serum Neurofilament Light Chain Is Associated with Incident Lacunes in Progressive Cerebral Small Vessel Disease

Nils Peters,Esther van Leijsen,Anil M. Tuladhar,Christian Barro,Marek J. Konieczny,Michael Ewers,Philippe Lyrer,Stefan T. Engelter,Jens Kuhle,Marco Duering,Frank-Erik de Leeuw 대한뇌졸중학회 2020 Journal of stroke Vol.22 No.3

Background and Purpose Serum neurofilament light (NfL)-chain is a circulating marker for neuroaxonal injury and is also associated with severity of cerebral small vessel disease (SVD) crosssectionally. Here we explored the association of serum-NfL with imaging and cognitive measures in SVD longitudinally. Methods From 503 subjects with SVD, baseline and follow-up magnetic resonance imaging (MRI) was available for 264 participants (follow-up 8.7±0.2 years). Baseline serum-NfL was measured by an ultrasensitive single-molecule-assay. SVD-MRI-markers including white matter hyperintensity (WMH)-volume, mean diffusivity (MD), lacunes, and microbleeds were assessed at both timepoints. Cognitive testing was performed in 336 participants, including SVD-related domains as well as global cognition and memory. Associations with NfL were assessed using linear regression analyses and analysis of covariance (ANCOVA). Results Serum-NfL was associated with baseline WMH-volume, MD-values and presence of lacunes and microbleeds. SVD-related MRI- and cognitive measures showed progression during follow-up. NfL-levels were associated with future MRI-markers of SVD, including WMH, MD and lacunes. For the latter, this association was independent of baseline lacunes. Furthermore, NfL was associated with incident lacunes during follow-up (P=0.040). NfL-levels were associated with future SVD-related cognitive impairment (processing speed: β=–0.159; 95% confidence interval [CI], –0.242 to –0.068; P=0.001; executive function β=–0.095; 95% CI, –0.170 to –0.007; P=0.033), adjusted for age, sex, education, and depression. Dementia-risk increased with higher NfL-levels (hazard ratio, 5.0; 95% CI, 2.6 to 9.4; P<0.001), however not after adjusting for age. Conclusions Longitudinally, serum-NfL is associated with markers of SVD, especially with incident lacunes, and future cognitive impairment affecting various domains. NfL may potentially serve as an additional marker for disease monitoring and outcome in SVD, potentially capturing both vascular and neurodegenerative processes in the elderly. Keywords Stroke; Dementia; Small vessel diseases; Neurofilament