Interactions Between Genetic Risk Score and Healthy Plant Diet Index on Cardiometabolic Risk Factors Among Obese and Overweight Women

Fatemeh Gholami,Mahsa Samadi,Niloufar Rasaei,Mir Saeid Yekaninejad,Seyed Ali Keshavarz,Gholamali Javdan,Farideh Shiraseb,Niki Bahrampour,Khadijeh Mirzaei 한국임상영양학회 2023 Clinical Nutrition Research Vol.12 No.3

People with higher genetic predisposition to obesity are more susceptible to cardiovascular diseases (CVDs) and healthy plant-based foods may be associated with reduced risks of obesity and other metabolic markers. We investigated whether healthy plant-foods-rich dietary patterns might have inverse associations with cardiometabolic risk factors in participants at genetically elevated risk of obesity. For this cross-sectional study, 377 obese and overweight women were chosen from health centers in Tehran, Iran. We calculated a healthy plant-based diet index (h-PDI) in which healthy plant foods received positive scores, and unhealthy plant and animal foods received reversed scores. A genetic risk score (GRS) was developed based on 3 polymorphisms. The interaction between GRS and h-PDI on cardiometabolic traits was analyzed using a generalized linear model (GLM). We found significant interactions between GRS and h-PDI on body mass index (BMI) (p = 0.02), body fat mass (p = 0.04), and waist circumference (p = 0.056). There were significant gene-diet interactions for healthful plant-derived diets and BMI-GRS on high-sensitivity C-reactive protein (p = 0.03), aspartate aminotransferase (p = 0.04), alanine transaminase (p = 0.05), insulin (p = 0.04), and plasminogen activator inhibitor 1 (p = 0.002). Adherence to h-PDI was more strongly related to decreased levels of the aforementioned markers among participants in the second or top tertile of GRS than those with low GRS. These results highlight that following a plant-based dietary pattern considering genetics appears to be a protective factor against the risks of cardiometabolic abnormalities.

On the generalized principally injective modules

Fatemeh Gholami,Zohreh Habibi,Alireza Najafizadeh 대한수학회 2024 대한수학회보 Vol.61 No.2

Some results are generalized from principally injective rings to principally injective modules. Moreover, it is proved that the results are valid to some other extended injectivity conditions which may be defined over modules. The influence of such injectivity conditions are studied for both the trace and the reject submodules of some modules over commutative rings. Finally, a correction is given to a paper related to the subject.

Application of the World Health Organization Quality of Life Instrument, Short Form (WHOQOL-BREF) to patients with cataract

Ali Gholami,Mahmood Tavakoli Araghi,Fatemeh Shamsabadi,Mahdiye Bayat,Fatemeh Dabirkhani,Farhad Moradpour,Kamyar Mansori,Yousef Moradi,Abdolhalim Rajabi 한국역학회 2016 Epidemiology and Health Vol.38 No.-

OBJECTIVES: Cataract is a prevalent disease in the elderly, and negatively influences patients’ quality of life. This study was conducted to study the application of the World Health Organization Quality of Life Instrument, Short Form (WHOQOL-BREF) to patients with cataract. METHODS: In this cross-sectional study, 300 patients with cataract were studied in Neyshabur, Iran from July to October 2014. The Iranian version of the WHOQOL-BREF questionnaire was used to measure their quality of life. Cronbach’s alpha coefficient, Pearson’s correlation coefficient, the paired t-test, the independent t-test, and a linear regression model were used to analyze the data in SPSS version 16.0 (SPSS Inc., Chicago, IL, USA). RESULTS: The mean age of the participants was 68.11±11.98 years, and most were female (53%). The overall observed Cronbach’s alpha coefficient for the WHOQOL-BREF was 0.889, ranging from 0.714 to 0.810 in its four domains. The total mean score of the respondents on the WHOQOL-BREF was 13.19. The highest and lowest mean scores were observed in the social relationship domain (14.11) and the physical health domain (12.29), respectively. A backward multiple linear regression model found that duration of disease and marital status were associated with total WHOQOL scores, while age, duration of disease, marital status, and income level were associated with domains one through four, respectively (p<0.05). CONCLUSIONS: The reliability analysis conducted in this study indicated that the WHOQOL-BREF scale exhibited an acceptable degree of internal consistency in the measurement of the quality of life of patients with cataract. It was also found that the patients with cataract who were surveyed reported a relatively moderate quality of life.

A novel approach to the form-finding of membrane structures using dynamic relaxation method

Labbafi, S. Fatemeh,Sarafrazi, S. Reza,Gholami, Hossein,Kang, Thomas H.K. Techno-Press 2017 Advances in computational design Vol.2 No.3

Solving a system of linear or non-linear equations is required to analyze any kind of structures. There are many ways to solve a system of equations, and they can be classified as implicit and explicit techniques. The explicit methods eliminate round-off errors and use less memory. The dynamic relaxation method (DR) is one of the powerful and simple explicit processes. The important point is that the DR does not require to store the global stiffness matrix, for which it just uses the residual loads vector. In this paper, a new approach to the DR method is expressed. In this approach, the damping, mass and time steps are similar to those of the traditional method of dynamic relaxation. The difference of this proposed method is focused on the method of calculating the damping. The proposed method is expressed such that the time step is constant, damping is equal to zero except in steps with maximum energy and the concentrated damping can be applied to minimize the energy of system in this step. In this condition, the calculation of damping in all steps is not required. Then the volume of computation is reduced. The DR method for form-finding of membrane structures is employed in this paper. The form-finding of the three plans related to the membrane structures with different loading is considered to investigate the efficiency of the proposed method. The numerical results show that the convergence rate based on the proposed method increases in all cases than other methods.

Review : An Environmentally Friendly and Efficient Method for Extraction of PHB Biopolymer with Non-Halogenated Solvents

( Asieh Aramvash ),( Narges Gholami Banadkuki ),( Fatemeh Moazzeni Zavareh ),( Samira Hajizadeh Turchi ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.11

The present study developed an efficient and environmentally friendly method for recovering polyhydroxybutyrate (PHB) from Cupriavidus necator. Several non-halogenated solvents were tested and it was found that butyl acetate and ethyl acetate are powerful solvents for the biopolymer. Testing was performed to examine the effects of temperature (25°C until temperature below solvent boiling points) and heating incubation time (0-60 min) on the two solvents. Butyl acetate had a higher recovery level (96%) and product purity (up to 99%) than ethyl acetate at 103°C and a heating incubation time of 30 min. Under these conditions, PHB recorded the highest molecular weight of 1.4 × 106 compared with the standard procedure (i.e., recovery using chloroform). The proposed strategy showed that butyl acetate is a good alternative to halogenated solvents such as chloroform for recovery of PHB.

The Association Between Dietary Energy Density and Musculoskeletal Pain in Adult Men and Women

Bahrampour Niki,Rasaei Niloufar,Gholami Fatemeh,Clark Cain C. T. 한국임상영양학회 2022 Clinical Nutrition Research Vol.11 No.2

Musculoskeletal pains (MPs), defined as persistent or recurrent pain, is a complex health problem. High overall calorie and fat intake have been related to obesity and MPs. Dietary energy density (DED), defined as energy content of food and beverages (in kcal) per unit total weight, has been associated with chronic muscle, cartilage, bone damage and pain. Thus, the purpose of this study is to investigate the association between DED and MPs in adult men and women. A total of 175 men and women (> 18 years) with MP participated in the study. A validated short form physical activity (PA) questionnaire, demographic, and McGill Pain Questionnaire were used. Anthropometric measurements were evaluated via standard protocols. Furthermore, a seven-day 24-hour recall of diet was used to determine the dietary intake. Total DED was calculated and divided into quartiles. Linear regression was used to discern the association between DED and MPs in adults. Participants assigned in the highest category of DED were characterized by lower intake of potassium, magnesium, vitamin C, folate, and fiber. However, results showed displayed higher intake of sodium, vitamin E, vitamin B3, fat, protein, cholesterol, saturated fatty acids, monounsaturated fatty acids, and polyunsaturated fatty acids (p < 0.001). Finally, after adjustment for confounders such as age, gender, PA, body mass index, waist circumference, education, job, marital status, history of some chronic diseases and vitamin C supplementation, a significant positive association was detected between DED and pain intensity. There was no significant association between DED and pain frequency in all models.

Association of Sleep Duration and Quality With Health-Related Quality of Life in Fresher University Students

Sharifnezhad Ahmad,Garmabi Maryam,Naderi Fatemeh,Darrudi Fateme,Andishmand Zahra,Gholami Ali 대한수면학회 2023 sleep medicine research Vol.14 No.1

Background and Objective Sleep duration and quality are important factors for health-related quality of life (HRQoL). This study aimed at investigating the association of sleep duration and quality with HRQoL in fresher students of Neyshabur University of Medical Sciences.Methods The study included 471 fresher students. The sleep duration and sleep quality were measured with the Persian version of Pittsburgh Sleep Quality Index (PSQI) and the HRQoL was evaluated with the Persian version of the 12-Item Short Form Survey (SF-12). The data were collected from late September to early October in 2019 and 2020. The multiple linear regression model was used to determine the independent association of sleep duration and quality with HRQoL. A p-value ≤ 0.05 was considered statistically significant.Results The mean age of the participants was 21.8 ± 6.0 years and the majority of them (62.4%) were female. The total HRQoL score and the prevalence of poor sleep quality were 81.6% and 28.0%, respectively. Among the students, 51.8% and 6.4% reported a sleep duration shorter than 7 hours and equal or more than 9 hours, respectively. The multiple linear regression model showed that excessive sleep duration (≥ 9 h) and sleep quality were associated with Mental Component Summary (MCS) and total HRQoL, respectively (p = 0.036, p = 0.018).Conclusions Referring to the results, enough and quality sleep has beneficial effects on HRQoL in students. Therefore, future strategies should be developed to improve sleep and consequently HRQoL among university students.