Effects of metal surface grinding at the porcelain try-in stage of fixed dental prostheses

Halil İbrahim Kılınç,Bülent Kesim,Hasan Önder Gümüş,Mehmet Dinçel,Selçuk Erkaya 대한치과보철학회 2014 The Journal of Advanced Prosthodontics Vol.6 No.4

PURPOSE. This study was to evaluate the effect of grinding of the inner metal surface during the porcelain try-in stage on metal-porcelain bonding considering the maximum temperature and the vibration of samples. MATERIALS AND METHODS. Ninety-one square prism-shaped (1 × 1 × 1.5 mm) nickel-chrome cast frameworks 0.3 mm thick were prepared. Porcelain was applied on two opposite outer axial surfaces of the frameworks. The grinding was performed from the opposite axial sides of the inner metal surfaces with a low-speed handpiece with two types of burs (diamond, tungsten-carbide) under three grinding forces (3.5 N, 7 N, 14 N) and at two durations (5 seconds, 10 seconds). The shear bond strength (SBS) test was performed with universal testing machine. Statistical analyzes were performed at 5% significance level. RESULTS. The samples subjected to grinding under 3.5 N showed higher SBS values than those exposed to grinding under 7 N and 14 N (P<.05). SBS values of none of the groups differed from those of the control group (P>.05). The types of bur (P=.965) and the duration (P=.679) did not affect the SBS values. On the other hand, type of bur, force applied, and duration of the grinding affected the maximum temperatures of the samples, whereas the maximum vibration was affected only by the type of bur (P<.05). CONCLUSION. Grinding the inner metal surface did not affect the metalporcelain bond strength. Although the grinding affected the maximum temperature and the vibration values of the samples, these did not influence the bonding strength.

Performance, blood and antioxidant status in dual-purpose laying hens supplemented with aqueous extract of Christ’s thorn jujube (Ziziphus spina-christi L.) leaves as phytogenic agent in subtropical conditions

El-Kholy Khaled H.,Tag El-Din Hasan,Tawfeek Found A.,Tufarelli Vincenzo,Losacco Caterina,Alhotan Rashed A.,Shafi Manal E.,Korish Mohamed A.,Attia Youssef A.,Hassab Sara H. M. 아세아·태평양축산학회 2024 Animal Bioscience Vol.37 No.5

Objective: The potential of aqueous extract of Christ’s thorn jujube (Ziziphus spina-christi) leaves (SLAE) to reduce the negative impacts of heat stress on production performance and physiological traits was investigated in dual-purpose layers under subtropical farming. Methods: A total of 200, 25-week-old laying hens (Inshas strain) were randomly assigned to four dietary treatments including SLAE at 0, 2.5, 5.0, and 7.5 mL/kg, respectively. The average temperature-humidity index value was 26.69 during the experimental period. The SLAE contained saponin (0.045%), total flavonoid content of 17.9 mg of quercetin equivalent/ 100 g and overall antioxidant capacity concentration of 17.9 mg of ascorbic acid equivalent/ 100 g. Results: The maximum final body weight (BW), BW gain, egg weight, number, and mass occurred at the level of SLAE7.5 inclusion. The egg quality was significantly higher in SLAE groups than in control, and overall, SLAE7.5 had the most favorable influence at 28 and 32 weeks. Liver and kidney function, as well as lipids profile, improved significantly by SLAE inclusion; the lowest concentrations of these parameters were in SLAE7.5 hens. Treatment with SLAE7.5 increased total antioxidant capacity and endogenous antioxidant enzymes compared to control, whereas no effect on superoxide dismutase was noticed. Conclusion: The addition of SLAE at 7.5 mL/kg diet improved egg laying performance and quality, metabolic profiles, and antioxidant status during hyperthermia conditions.

Synthesis and Quartemization of 6-(Substitutedamino)-Purines with Antitumor Activity Screening

El-Bayouki, Khairy-A.M.,Basyouni, Wahid-M.,El-Din, S.M.,Habeeb, A.G. The Pharmaceutical Society of Korea 1994 Archives of Pharmacal Research Vol.17 No.2

Reaction of c-chloro-9-benzyl-8-(methylthio)purine 3 with primary amines afforoded, the comesponding 6-(substitutedamino)purines 4a-g. The latter products when methylated with methyl iodide yielded smoothly $N^3$-methyl purinium iodide salts 5a-f rather than the probable $N^1\;and\;N^7$-derivatives. 9-Benzyl-3-methyl-6-(methylmino)-8-(methylthio)purine 8 was obtained upon treating the purinium iodide 5a with alkali. Most of the synthesized compounds were screened for their antitumor activity.

Does anaesthesia in mothers during delivery affect bilirubin levels in their neonates?

El-Kabbany, Zeinab A,Toaima, Nadin N,Toaima, Tamer N,EL-Din, Mona Y Gamal The Korean Pediatric Society 2017 Clinical and Experimental Pediatrics (CEP) Vol.60 No.12

Purpose: This study aimed to assess whether different anesthetic techniques and oxytocin use applied during delivery affect transcutaneous bilirubin levels during the first 24 hours in neonates. Methods: A total of 1,044 neonates delivered by either caesarian section (C/S) or normal vaginal delivery (NVD) were included in the study. They were classified into 5 groups as follows: group 1: born by C/S using general anesthesia, group 2: C/S using spinal anaesthesia, group 3: C/S using general anesthesia after failed spinal block, group 4: by NVD without anesthesia, and group 5: oxytocin-induced vaginal delivery without anesthesia. Transcutaneous total bilirubin levels (TBLs) were measured during the first 24 hours and on the fifth and eighth days of life and the levels in different groups were compared. Results: The TBLs were significantly higher in neonates delivered by C/S using general anesthesia rather than spinal anesthesia (P<0.001), and both groups had higher levels than those born by NVD without anesthesia ($P{\leq}0.001$). However, the group receiving general anesthesia after failed spinal block was found to have the highest bilirubin level. Moreover, TBLs were significantly higher with the use of oxytocin ($P{\leq}0.001$). Conclusions: C/S and general anesthesia adversely affect the bilirubin levels in neonates, and the use of oxytocin during vaginal delivery also increases TBLs in neonates.

Testing unknown age classes of life distributions based on TTT-transform

El-Din, M.M. Mohie,Abu-Youssef, S.E.,Ali, Nahed S.A. The Korean Reliability Society 2013 International Journal of Reliability and Applicati Vol.14 No.1

A nonparametric procedure for testing exponentially against used better than aged in expectation (UBAE) class of life distributions is presented. We construct a test statistics based on scaled total time on test (TTT)-transformation, to test exponentiality against UBAE class of life distributions. The distribution of the statistic is investigated via simulation. Practical applications of the proposed test are presented.

Adulticidal, larvicidal and biochemical properties of essential oils against Culex pipiens L

Hossam El-Din M. Zahran,Hamdy K. Abou-Taleb,Samir A.M. Abdelgaleil 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.1

In this study, the insecticidal properties of sixteen essential oils isolated from Egyptian plants were evaluated against the fourth instar larvae and adults of Culex pipiens L. The inhibitory effects of most active essential oils on the activity of acetylcholinesterase (AChE) and adenosine triphosphatases (ATPases) were also tested. In larvicidal assay against Cx. pipiens, the oils of Artemisiamonosperma, S. terebinthifolius and Origanumvulgare showed the highest insecticidal activity with LC50 values of 7.73, 8.14 and 8.40 mg/l after 24 h of treatment and 2.63, 3.46 and 6.74mg/l after 48 h of treatment.On the contrary, the oils of Schinusmolle and Rosmarinus officinalis were the less effective. The results of fumigant toxicity assay against the adults of Cx. pipiens revealed that the tested oils had remarkable toxicity based on their LC50 valueswhich ranged between 0.06 and 12.84 mg/l. The oil of Artemisia judaicawas the most activewith an estimated LC50 value of 0.06mg/l air after 24 h of treatment, while the oil of Citrus paradisi was less active. The essential oils of A. monosperma, O. vulgare, S. terebinthifolius and C. paradisi elicitedmarked enzymatic inhibition towards AChE and ATPases isolated fromCx. pipiens larvae. These results indicated that the essential oils have potential for the development of natural larvicides and fumigants for Cx. pipiens control.

Synthesis and broad-spectrum antiproliferative activity of diarylamides and diarylureas possessing 1,3,4-oxadiazole derivatives

Gamal El-Din, M.M.,El-Gamal, M.I.,Abdel-Maksoud, M.S.,Yoo, K.H.,Oh, C.H. Pergamon Press 2015 Bioorganic & medicinal chemistry letters Vol.25 No.8

A series of diarylamides and diarylureas possessing 1,3,4-oxadiazole scaffold was designed and synthesized. Their in vitro antiproliferative activities were tested against a panel of 58 cell lines of nine different cancer types at the NCI, and compared with Sorafenib as a reference compound. Most of the compounds showed strong and broad-spectrum antiproliferative activities. The diarylurea compound 2g possessing 4-chloro-3-(trifluoromethyl)phenyl terminal moiety showed the highest mean % inhibition value of about 100% over the 58-cell line panel at 10μM concentration. Also compounds 2h, 2l, 2m exhibited mean % inhibition over 90% at 10μM concentration. The IC<SUB>50</SUB> value of compound 2b over SNB-75 CNS cancer cell line was 0.65μM. Compound 2h also exerted submicromolar IC<SUB>50</SUB> values of 0.67, 0.80, and 0.87μM against PC-3 prostate cancer cell line, HCT-116 colon cancer cell line, and ACHN renal cancer cell line, respectively. Compound 2h showed comparable efficacy to Sorafenib.

Utilization of Sunitinib for Renal Cell Cancer: an Egyptian University hospital experience

Ezz El Din, M Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.7

Background: Metastatic renal cell carcinoma (mRCC) status as poor prognosis improved with the introduction of tyrosine-kinase inhibitors, especially sunitinib. There is sparse data reporting from our region on use of sunitinib in metastatic RCC. Thus the present study explores sunitinib usage at our institute. Materials and Methods: An unselected population of patients with metastatic RCC receiving sunitinib was analyzed with respect to patient characteristics, response, toxicity, and outcomes. Results: Fourty-nine patients with a median age of 50.5 years (range 21-71 years) were included. Most were male (61.2%). Twenty‑one (42.9%) had metastatic disease at presentation. Sunitinib was first line therapy in 45. Conventional clear cell carcinoma was the most common pathology present (39 patients; 79.59 %). The most common site of metastasis was the lung (75.5%). Most patients (30) were started at a dose of 50 mg once a day for 4 weeks and then 2 weeks rest. Clinical benefit rate was 73.5% (n= 36), and 22.5% (n= 11) demonstrated progressive disease at first imaging evaluation within the first 3-6 months. The following objective response performed for patients was 48.9% (n=24) and progression at 24.5 % (n=12). The median follow‑up was 16 months (range, 4-34 months), the overall estimated median PFS was 9 months and the estimated median OS was 15 months. Conclusions: This study demonstrated sunitinib is tolerable and effective in advanced/metastatic RCC Egyptian patients and indicates we should further seek second and third lines to increase survival equivalence as reported in the worldwide literature.

Insecticidal and developmental inhibitory properties of monoterpenes on Culex pipiens L. (Diptera: Culicidae)

Hossam El-Din M. Zahran,Samir A.M. Abdelgaleil 한국응용곤충학회 2011 Journal of Asia-Pacific Entomology Vol.14 No.1

Twelve monoterpenes were evaluated for larvicidal and adulticidal activities towards Culex pipiens. Geraniol and cuminaldehyde were the most toxic monoterpenes to larvae, with LC_50 values of 38.6 and 38.9 mg/l after 24 h of treatment, respectively, whereas cuminaldehyde was the most potent compound after 48 h of treatment, followed by geraniol and thymol. In fumigant toxicity experiments, (R)-carvone and geraniol were the most toxic monoterpenes against the adults at all three tested concentrations and after both 24 and 48 h. When tested at sublethal concentrations (0.5 LC_50), (R)-carvone, (S)-limonene and cuminaldehyde decreased hatchability, pupation and adult emergence and induced high larval mortality. Our results suggest that geraniol, cuminaldehyde and (R)-carvone are promising toxicants against Culex pipiens and could be useful in the search for new natural insecticides.

Seismic performance of pile-founded fixed jacket platforms with chevron braces

Nour El-Din, Mohamed,Kim, Jinkoo Taylor & Francis 2015 STRUCTURE AND INFRASTRUCTURE ENGINEERING Vol.11 No.6