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Recent Development in the Rate Performance of Li4Ti5O12
Chunfu Lin,Li Lu,Yuelong Xin,Fuquan Cheng,Man On Lai,Henghui Zhou 한국진공학회 2014 Applied Science and Convergence Technology Vol.23 No.2
Lithium-ion batteries (LIBs) have become popular electrochemical devices. Due to the unique advantages of LIBs in terms of high operating voltage, high energy density, low self-discharge, and absence of memory effects, their application range, which was primarily restricted to portable electronic devices, is now being extended to high-power applications, such as electric vehicles (EVs) and hybrid electrical vehicles (HEVs). Among various anode materials, Li4Ti5O12 (LTO) is believed to be a promising anode material for high-power LIBs due to its advantages of high working potential and outstanding cyclic stability. However, the rate performance of LTO is limited by its intrinsically low electronic conductivity and poor Li+ ion diffusion coefficient. This review highlights the recent progress in improving the rate performance of LTO through doping, compositing, and nanostructuring strategies.
Recent Development in the Rate Performance of Li4Ti<SUB>5</SUB>O<SUB>12</SUB>
Chunfu Lin,Yuelong Xin,Fuquan Cheng,Man On Lai,Henghui Zhou,Li Lu 한국진공학회(ASCT) 2014 Applied Science and Convergence Technology Vol.23 No.2
Lithium-ion batteries (LIBs) have become popular electrochemical devices. Due to the unique advantages of LIBs in terms of high operating voltage, high energy density, low self-discharge, and absence of memory effects, their application range, which was primarily restricted to portable electronic devices, is now being extended to high-power applications, such as electric vehicles (EVs) and hybrid electrical vehicles (HEVs). Among various anode materials, Li4Ti5O12 (LTO) is believed to be a promising anode material for high-power LIBs due to its advantages of high working potential and outstanding cyclic stability. However, the rate performance of LTO is limited by its intrinsically low electronic conductivity and poor Li<SUP>+</SUP> ion diffusion coefficient. This review highlights the recent progress in improving the rate performance of LTO through doping, compositing, and nanostructuring strategies.
Recent Development in the Rate Performance of Li<sub>4</sub>Ti<sub>5</sub>O<sub>12</sub>
Lin, Chunfu,Xin, Yuelong,Cheng, Fuquan,Lai, Man On,Zhou, Henghui,Lu, Li The Korean Vacuum Society 2014 Applied Science and Convergence Technology Vol.23 No.2
Lithium-ion batteries (LIBs) have become popular electrochemical devices. Due to the unique advantages of LIBs in terms of high operating voltage, high energy density, low self-discharge, and absence of memory effects, their application range, which was primarily restricted to portable electronic devices, is now being extended to high-power applications, such as electric vehicles (EVs) and hybrid electrical vehicles (HEVs). Among various anode materials, $Li_4Ti_5O_{12}$ (LTO) is believed to be a promising anode material for high-power LIBs due to its advantages of high working potential and outstanding cyclic stability. However, the rate performance of LTO is limited by its intrinsically low electronic conductivity and poor $Li^+$ ion diffusion coefficient. This review highlights the recent progress in improving the rate performance of LTO through doping, compositing, and nanostructuring strategies.
Huang, Gang,Zhang, Chunfu,Li, Shunzi,Khemtong, Chalermchai,Yang, Su-Geun,Tian, Ruhai,Minna, John D.,Brown, Kathlynn C.,Gao, Jinming Royal Society of Chemistry 2009 Journal of materials chemistry Vol.19 No.35
<P>Superparamagnetic iron oxide (SPIO) nanoparticles are widely used in magnetic resonance imaging (MRI) as versatile ultra-sensitive nanoprobes for cellular and molecular imaging of cancer. In this study, we report a one-step procedure for the surface functionalization of SPIO nanoparticles with a lung cancer-targeting peptide. The hydrophobic surfactants on the as-synthesized SPIO are displaced by the peptide containing a poly(ethylene glycol)-tethered cysteine residue through ligand exchange. The resulting SPIO particles are biocompatible and demonstrate high T<SUB>2</SUB> relaxivity. The nanoprobes are specific in targeting α<SUB>v</SUB>β<SUB>6</SUB>–expressing lung cancer cells as demonstrated by MR imaging and Prussian blue staining. This facile surface chemistry and the functional design of the proposed SPIO system may provide a powerful nanoplatform for the molecular diagnosis of lung cancer.</P> <P>Graphic Abstract</P><P>Surface functionalization of SPIO nanoparticles with lung cancer peptides enables the specific targeting to α<SUB>v</SUB>β<SUB>6</SUB>–positive H2009 cancer cells, verified by cell uptake and MR imaging. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b902358e'> </P>
Changhong Wang,Shan Qi,Cheng Xie,Chunfu Li,Pu Wang,Dongmei Liu 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.6
Objective: The present study is to evaluate the biological functions of long non-coding RNA (lncRNA), X-inactive specific transcript, X-inactive specific transcript (XIST) in human epithelial ovarian cancer (EOC). Methods: XIST was upregulated in EOC cell lines, CAOV3 and OVCAR3 cells by lentiviral transduction. The effects of XIST overexpression on cancer cell proliferation, invasion, chemosensitivity and in vivo tumor growth were investigated, respectively. Possible sponging interaction between XIST and human microRNA hsa-miR-214-3p was further evaluated. Furthermore, hsa-miR-214-3p was overexpressed in XIST-upregulated CAOV3 and OVCAR3 cells to evaluate its effect on XIST-mediated EOC regulation. Results: Lentivirus-mediated XIST upregulation had significant anticancer effects in CAOV3 and OVCAR3 cells by suppressing cancer cell proliferation, invasion, increasing cisplatin chemosensitivity and inhibiting in vivo tumor growth. Hsa-miR-214-3p was confirmed to directly bind XIST, and inversely downregulated in XIST-upregulated EOC cells. In EOC cells with XIST upregulation, secondary lentiviral transduction successfully upregulated hsa-miR-214-3p expression. Subsequently, hsa-miR-214-3p upregulation functionally reversed the anticancer effects of XIST-upregulation in EOC. Conclusion: Upregulation of lncRNA XIST may suppress EOC development, possibly through sponging effect to induce hsa-miR-214-3p downregulation.