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RISS 인기검색어
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- 저자 : Chaofan Hu (검색결과 3 건)
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Chaofan Hu,Yingliang Liu,Jianhua Rong,Qingqing Liu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.8
A novel strategy toward one-pot hydrothermal synthesis of copper sulfide nanoplates-decorated reduced graphene oxide (RGO–CuS) composites was developed. CuS nanoplates were successfully loaded onto the surface of RGO in the hydrothermal procedure, which was confirmed by transmission electron microscopy, UV-Vis–NIR and Raman spectroscopy. The as-synthesized RGO–CuS composites showed pronounced enhanced optical absorbance in near infrared (NR) region and higher photothermal conversion efficiency than noncomposite GO and CuS nanoplates. The RGO–CuS materials were used in photothermal ablation of cancer cells with a 980 nm laser irradiation and showed improved performance than CuS nanoplates.
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Upregulated lncRNA Gm2044 inhibits male germ cell development by acting as miR-202 host gene
Meng Liang,Ke Hu,Chaofan He,Jinzhao Zhou,Yaping Liao 한국통합생물학회 2019 Animal cells and systems Vol.23 No.2
Long non-coding RNAs (lncRNAs) have been found to participate in the regulation of human spermatogenic cell development. However, little is known about the abnormal expression of lncRNAs associated with spermatogenic failure and their molecular mechanisms. Using lncRNA microarray of testicular tissue for male infertility and bioinformatics methods, we identified the relatively conserved lncRNA Gm2044 which may play important roles in non-obstructive azoospermia. The UCSC Genome Browser showed that lncRNA Gm2044 is the miR-202 host gene. This study revealed that lncRNA Gm2044 and miR-202 were significantly increased in nonobstructive azoospermia of spermatogonial arrest. The mRNA and protein levels of Rbfox2, a known direct target gene of miR-202, were regulated by lncRNA Gm2044. Furthermore, the miR- 202-Rbfox2 signalling pathway was shown to mediate the suppressive effects of lncRNA Gm2044 on the proliferation of human testicular embryonic carcinoma cells. Understanding of the molecular signalling pathways for lncRNA-regulated spermatogenesis will provide new clues into the pathogenesis and treatment of patients with male infertility.
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Jiemin Qiu,Weihao Ye,Congcong Chen,Zhiqiang Xu,Chaofan Hu,Jianle Zhuang,Hanwu Dong,Bingfu Lei,Guangqi Hu,Yingliang Liu 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.117 No.-
UV absorbers are sustainable substances that inhibit the ultraviolet (UV) radiative degradation of polymers. In previous reports, the as-prepared carbon dots (CDs) possess only an absorption band at UVA(320–400 nm). To achieve broad-spectrum UV absorption (200–400 nm), increasing the concentrationof the CDs solution becomes common. However, a high concentration solution seriously affects the lighttransmittance due to its heavy yellow color. Furthermore, the promising organic UV absorbers cannotachieve broad-spectrum UV absorption. In this work, we initially synthesized three-component watersolublecarbon dots (OP–CDs), which delivers an excellent UV absorption (98 % UVA and 100 % UVB atthe concentration of 1.7 102 mg/mL; 99 % transmittance in visible light). Moreover, OP–CDs exhibitoutstanding stability at high temperatures and different pH. With the corporation of OP–CDs and polyvinylalcohol (PVA), a high-performance UV-shielding film was formed, leading to enhanced broadspectrumUV shielding performance and improved mechanical properties, resistance of photocatalyticactivity and anti-UV aging ability compared with pure PVA film. Notably, the PVA film remains hightransparency with the addition of OP–CDs. The study suggests that the corporation of OP–CDs and polymersis effective in anti-UV degradation.
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