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- 저자 : Changyin Feng (검색결과 1 건)
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Fang Nie,Changyin Feng,Naveed Ahmad,Mengfei Tian,Qinglong Liu,Weihao Wang,Ziqi Lin,Chunying Li,Chunjian Zhao 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.118 No.-
Echinacoside and acteoside, the representative constituents of Cistanche deserticola Y. C. Ma (C. deserticola),are known for its many important biological activities. In this study, a novel ternary natural deepeutectic solvent (NADES) (citric acid, fructose and glucose in a 1:2:1 molar ratio, 30 % water content)was obtained through the adjustment and optimization of single-factor experiments. And through theBox-Behnken design optimization, the optimal extraction conditions were obtained, at the moment,the yields of echinacoside and acteoside were 6.16 and 2.13 mg/g, respectively. In addition, through computermolecular simulation, it was found that there are strong hydrogen bonds and interactions betweenthe molecules of NADES, and the hydrogen bonds, van der Waals forces and p-p interactions played animportant role in the extraction of echinacoside and acteoside from C. deserticola by NADES. Finally, comparedwith the traditional method, NADES ultrasound-assisted extraction of echinacoside and acteosidehas a shorter time (15 min), the maximum extraction yield is 1.54–2.86 times and 1.26–2.52 times thanthat of traditional extraction methods for echinacoside and acteoside, respectively. This study demonstratesthat NADES can provides a new direction for developing new sustainable alternatives, improvinggreen extraction process and efficiency for extracting natural active substances.
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