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- 저자 : Buragohain, Alak Kumar (검색결과 4 건)
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Poly Buragohain,Peng Lin,Ankit Garg,Sreedeep S,David Hui 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.12
Inorganic macro cations (Na+, K+ and Ca+) co-exist in agricultural and municipal landfill sites. The retention behavior of these ions in different soils and combinations (binary and ternary system) has not been fully understood by previous studies. This study seeks to probe into the retention behavior of macro cations (Na+, K+, Ca+2) in six different soils under multiple combinations of ions solution. The retention of common ions was quantified by using Freundlich and Langmuir isotherms. Na+ (single) pollutant-soil interaction was desorbed in most of the soils. The retention of K+ and Ca+2 was much greater than that of Na+. There is no definite trend for retention of Na+ in the presence of K+. For all soils, the retention results of K+ in the presence of Na+ decreased. Affinity for K+ was greater than that for Ca+2 in most of the soils. This study also demonstrated the affinity sequence of the ion retention for each soil and the percentage reduction of ions in competition with respect to single ions. Anomalous trends of the isotherm parameter fitting suggested the limitation of the mathematical models in predicting the experimental data. These results can be helpful in improving accuracy of fate prediction of pollutant fate and thus, design of waste containment facilities for various wastes that contains inorganic ions.
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Dey, Tapan,Dutta, Prachurjya,Manna, Prasenjit,Kalita, Jatin,Boruah, Hari Prasanna Deka,Buragohain, Alak Kumar,Unni, Balagopalan The Korean Society of Applied Pharmacology 2018 Biomolecules & Therapeutics(구 응용약물학회지) Vol.26 No.4
Vasicinone, a quinazoline alkaloid from Adhatoda vasica Nees. is well known for its bronchodilator activity. However its anti-proliferative activities is yet to be elucidated. Here-in we investigated the anti-proliferative effect of vasicinone and its underlying mechanism against A549 lung carcinoma cells. The A549 cells upon treatment with various doses of vasicinone (10, 30, 50, $70{\mu}M$) for 72 h showed significant decrease in cell viability. Vasicinone treatment also showed DNA fragmentation, LDH leakage, and disruption of mitochondrial potential, and lower wound healing ability in A549 cells. The Annexin V/PI staining showed disrupted plasma membrane integrity and permeability of PI in treated cells. Moreover vasicinone treatment also lead to down regulation of Bcl-2, Fas death receptor and up regulation of PARP, BAD and cytochrome c, suggesting the anti-proliferative nature of vasicinone which mediated apoptosis through both Fas death receptors as well as Bcl-2 regulated signaling. Furthermore, our preliminary studies with vasicinone treatment also showed to lower the ROS levels in A549 cells and have potential free radical scavenging (DPPH, Hydroxyl) activity and ferric reducing power in cell free systems. Thus combining all, vasicinone may be used to develop a new therapeutic agent against oxidative stress induced lung cancer.
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Rathore Divya,Divyanth L. G.,Reddy Kaamala Lalith Sai,Chawla Yogesh,Buragohain Mridula,Soni Peeyush,Machavaram Rajendra,Hussain Syed Zameer,Ray Hena,Ghosh Alokesh 한국농업기계학회 2023 바이오시스템공학 Vol.48 No.2
Purpose The process of robotic harvesting has revolutionized the agricultural industry, allowing for more effi cient and costeff ective fruit picking. Developing algorithms for accurate fruit detection is essential for vision-based robotic harvesting of apples. Although deep-learning techniques are popularly used for apple detection, the development of robust models that can accord information about the fruit’s occlusion condition is important to plan a suitable strategy for end-eff ector manipulation. Apples on the tree experience occlusions due to leaves, stems (branches), trellis wire, or other fruits during robotic harvesting. Methods A novel two-stage deep-learning-based approach is proposed and successfully demonstrated for detecting ontree apples and identifying their occlusion condition. In the fi rst stage, the system employs a cutting-edge YOLOv7 model, meticulously trained on a custom Kashmiri apple orchard image dataset. The second stage of the approach utilize the powerful Effi cientNet-B0 model; the system is able to classify the apples into four distinct categories based on their occlusion condition, namely, non-occluded, leaf-occluded, stem/wire-occluded, and apple-occluded apples. Results The YOLOv7 model achieved an average precision of 0.902 and an F1-score of 0.905 on a test set for detecting apples. The size of the trained weights and detection speed were observed to be 284 MB and 0.128 s per image. The classifi cation model produced an overall accuracy of 92.22% with F1-scores of 94.64%, 90.91%, 86.87%, and 90.25% for nonoccluded, leaf-occluded, stem/wire-occluded, and apple-occluded apple classes, respectively. Conclusion This study proposes a novel two-stage model for the simultaneous detection of on-tree apples and classify them based on occlusion conditions, which could improve the eff ectiveness of autonomous apple harvesting and avoid potential damage to the end-eff ector due to the objects causing the occlusion.
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Tapan Dey,Prachurjya Dutta,Prasenjit Manna,Jatin Kalita,Hari Prasanna Deka Boruah,Alak Kumar Buragohain,Balagopalan Unni 한국응용약물학회 2018 Biomolecules & Therapeutics(구 응용약물학회지) Vol.26 No.4
Vasicinone, a quinazoline alkaloid from Adhatoda vasica Nees. is well known for its bronchodilator activity. However its antiproliferative activities is yet to be elucidated. Here-in we investigated the anti-proliferative effect of vasicinone and its underlying mechanism against A549 lung carcinoma cells. The A549 cells upon treatment with various doses of vasicinone (10, 30, 50, 70 μM) for 72 h showed significant decrease in cell viability. Vasicinone treatment also showed DNA fragmentation, LDH leakage, and disruption of mitochondrial potential, and lower wound healing ability in A549 cells. The Annexin V/PI staining showed disrupted plasma membrane integrity and permeability of PI in treated cells. Moreover vasicinone treatment also lead to down regulation of Bcl-2, Fas death receptor and up regulation of PARP, BAD and cytochrome c, suggesting the anti-proliferative nature of vasicinone which mediated apoptosis through both Fas death receptors as well as Bcl-2 regulated signaling. Furthermore, our preliminary studies with vasicinone treatment also showed to lower the ROS levels in A549 cells and have potential free radical scavenging (DPPH, Hydroxyl) activity and ferric reducing power in cell free systems. Thus combining all, vasicinone may be used to develop a new therapeutic agent against oxidative stress induced lung cancer.
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