http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Barakat Mahmoud M. (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
-
Unique Phenolic Sulphate Conjugates from the Flowers of Tamarix amplexicaulis
Sahar A. M. Hussein,Amani M. D. El-Mousallamy,Mahmoud A. M. Nawwar,Ahmed A. M. Souleman,Heba H. Barakat 한국생약학회 1998 Natural Product Sciences Vol.4 No.4
The unique sulphated phenolics, gallic acid 3-methyl ether 5-potassium sulphate, isoferulic acid 3-potassium sulphate, and ellagic acid 4,4`-dimethyl ether 3-potassium sulphate have been isolated from the flowers of Tamarix amplexicaulis Ehrenb. (Tamaricaceae). The hitherto unknown natural phenolic acid, gallic acid 3-methyl ether, together with the known phenolic, gallic acid, gallic acid 4-methyl ether, isoferulic acid, ferulic acid, ellagic acid, and ellagic acid 4,4`-dimethyl ether have been also separated and characterized. The structures were established by conventional methods, including electrophoretic analysis and confirmed by ESIMS, ¹H- and <sup>13</sup>C-NMR.
-
Anti-cancer Effect of Hyoscyamus muticus Extract via Its Activation of Fas/FasL-ASK1-p38 Pathway
Amer Ali Abd El-Hafeez,Hala Mohamed M. Marzouk,Mohamed A. A. Abdelhamid,Hazim O. Khalifa,Tamer H. A. Hasanin,Ahmed G. K. Habib,Fatma Mahmoud Abdelwahed,Fatma M. Barakat,Eslam M. Bastawy,Eman M. B. Abd 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.5
Hyoscyamus muticus L. is a traditional medicine used as antispasmodic and sedative. Herein, we aimed to determine the phytochemical constituents and for the first time its anti-cancer activities. The phytochemical constituents of the different extracts were evaluated by calorimetric methods. The anti-cancer activities of the extracts were tested against leukemia, breast, renal, and prostate cancers cell lines. 4, 6-Diamidino-2-phenylindole (DAPI) staining, flow cytometric analysis, knockdown of ASK1, and reactive oxygen species (ROS) production were evaluated to clarify the mechanism of action. Phytochemical screening confirmed the presence of wide range of phytoconstituents. Hyoscyamus muticus methanolic extracts (HMME) showed the highest anti-cancer activities against leukemia, breast, renal, and prostate cancers as compared to ethanol and aqueous extracts. Specifically, HMME exerted cytotoxic effect against the MDA-MB-231 and MDA-MB-468 triple-negative breast cancer (TNBC) cell lines with IC50 values of 8.75 and 7.25 μg/mL, respectively. Mechanistically, DAPI staining and flow cytometric analysis revealed that HMME induces apoptosis via the death receptor, FAS, but not the mitochondrial pathway. Moreover, ASK1 and p38 were rapidly activated in response to HMME, and knockdown of ASK1 by a small interference of RNA specific to Ask1 attenuated p38 and caspase-3 activation and suppressed apoptosis, implying that HMME-induced apoptosis relies on the ASK1-p38-caspase-3 pathway. Furthermore, we confirmed that cellular ROS generation was a critical mediator in HMME-induced apoptosis because the ROSscavenger N-acetyl cysteine significantly decreased the phosphorylation of ASK1 and HMME-induced apoptosis. Our results confirmed HMME cytotoxic effects in TNBCs via ROS-dependent activation of the Fas/FasL-ASK1-p38 axis.
-
Micro-grid Monitoring and Supervision: Web-based SCADA Approach
Ali Mohamed A.,Barakat Mahmoud M.,Abokhalaf Masoud M.,Fadel Yasmin H.,Kandil Mohamed,Rasmy Mariam W.,Ali Osama N.,Besheer Ahmad H.,Emara Hassan M.,Bahgat Ahmed 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.5
Owing to the widespread use of the micro-grid concept to serve many real life applications, the main concern of this paper is to monitor, evaluate and manage the operational performance of an existent, already installed micro-grid that consists of On & Off grid PV systems in addition to the main grid supply. With the aid of customized web based SCADA system fully designed by authors, the performance evaluation of the proposed micro-grid is carried out in terms of energy consumption, power quality indices and energy cost based on Egypt’s energy current tariff . The designed system helps in both micro-grid status monitoring as well as load sharing between the main grid supply and the off grid PV energy system. The data of the on grid PV energy system are accessed and collected online directly from the inverter web server instead of downloading them offl ine from the PV inverter. In this case, data are analyzed with a reasonable refresh rate, which saves time and eff ort. Remote access platform is developed securely through a multi-level security authentication and strong data encryption using the OpenVPN protocol under the Dynamic Domain Name System service. Smart wired and wireless technology—used as integrated sensing devices to the developed SCADA system—enables easy system installation and running cost saving. Finally, to validate the collected data from the newly SCADA designed monitoring system, a performance characterization for the on grid PV system following international standards of yields calculations is carried out for 3 months in 2019.
-
Copper Ion Cementation in Presence of a Magnetic Field
Fadali, Olfat A.,Obaid, Mohamed,Mahmoud, Mohamed S.,Farrag, Taha E.,TaeWoo, Kim,Khalil, Khalil Abdelrazek,Barakat, Nasser A. M. VCH VERLAGSGESELLSCHAFT 2015 CHEMICAL ENGINEERING AND TECHNOLOGY Vol.38 No.3
<P><B>Abstract</B></P><P>The effect of an electromagnetic field (EMF) on the rate of copper(II) cementation from copper sulfate solutions on a rotating iron cylinder was investigated. The studied variables were cylinder rotation speed, magnetic field strength, and magnetic field direction. The application of EMF increased the rate of cementation in both parallel and perpendicular direction of the magnetic field where the latter proved to be more effective. The rate of mass transfer under an EMF was found to be more than doubled. The enhancement of copper recovery in presence of the EMF is due to the induced motion of Fe<SUP>+</SUP><I><SUP>n</SUP></I> in the solution which is limited to a certain range of cylinder rotation speed. The power consumption for cementation of copper could be significantly reduced by utilizing EMF.</P>
ScienceON
DBpia연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
