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Assessment of Breast Cancer Patients' Knowledge and Decisional Conflict Regarding Tamoxifen Use
Kim, Se Ik,Lee, Yumi,Son, Yedong,Jun, So Yeun,Yun, Sooin,Bae, Hyo Sook,Lim, Myong Cheol,Jung, So-Youn,Joo, Jungnam,Lee, Eun Sook The Korean Academy of Medical Sciences 2015 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.30 No.11
<P>Breast cancer is the most common type of female cancer. Tamoxifen, a selective estrogen receptor modulator, is widely used to decrease breast cancer recurrence and mortality among patients. However, it also increases the risk of endometrial cancer. This study aimed to assess knowledge and decisional conflict regarding tamoxifen use. Between June and October 2014, breast cancer patients using tamoxifen were consecutively screened and requested to complete a survey including the EQ-5D, Satisfaction with Decision Scale (SWD), Decisional Conflict Scale (DCS), and a self-developed, 15-item questionnaire measuring tamoxifen-related knowledge. The study sample comprised 299 patients. The mean total knowledge score was 63.4 of a possible 100.0 (range, 13.3-93.3). While 73.9% of the participants knew that tamoxifen reduces the risk of breast cancer recurrence, only 57.9% knew that the drug increases endometrial cancer risk. A higher education level (≥college) was associated with a higher, total knowledge score (β = 4.291; <I>P</I> = 0.017). A higher knowledge score was associated with a decreased DCS score (β = -0.366; <I>P</I> < 0.001). A higher SWD score was also associated with decreased decisional conflict (β = -0.178; <I>P</I> < 0.001). In conclusion, the breast cancer patients with higher levels of tamoxifen-related knowledge showed lower levels of decisional conflict regarding tamoxifen use. Clinicians should provide the exact information about tamoxifen treatment to patients, based on knowledge assessment results, so as to aid patients' decision-making with minimal conflict.</P>
Molecular Systematics of Korean Cobitids Based on Mitochondrial Cytochrome b Sequence
Kim, So-Young,Kim, Chang-Bae,Kim, Ik-Soo,Park, Jong-Young,Park, Ho-Yong The Korean Society for Integrative Biology 2002 Korean journal of biological sciences Vol.6 No.1
We compared the complete mitochondrial cytochrome b gene sequences of Korean and European cobitids to provide independent evidence for assessment of systematic and biogeographic relationships of species in the genus Cobitis. The data suggested monophyly of the genus Cobitis and the inclusion of Korean Cobitis species within the group having one lamina circularis, a primitive condition. Also, all the phylogenetic analyses using maximum parsimony, maximum likelihood, and neighbor joining methods showed a monophyletic relationship among Cobitis. The basal position of the Caspian C. cf. sibirica reported here reflects the eastern Asiatic origin cf. the European Cobitis and establishes C. cf. sibirica as an independent lineage. The Korean C. pacifica diverged next to C. cf. sibirica in basal group from the genus Cobitis. This result is in agreement with the hypothesized Asiatic origin of some European freshwater fish lineages. The phylogenetic relationships in this study showed a close affinity between C. zanadreai and C. sinensis. Two new species, C. tetralineata and C. pacifica in Korea also are closely related to monophyletic group clustering the type species of the Acanestrinia subgenus (C. elongata) with all the endemic Italian species (C. bilineata and C. zanandreai). This may suggest that the affinity between the Korean and Danubian-Italian imply genetic convergence or genetic plesiomorphic state between allopatric species that are separated for the Miocene. The mtDNA-based phylogeny for the species of the genus Cobitis from Kores and Europe permits phylogenetic assessment of the morphological transitions of Iamina circularis.
배정익(Bae, Jung-Ik),안병욱(An, Byung-Wook),박동소(Park, Tong-So),이상호(Lee, Sang-Ho),이경회(Lee, Kyung-Hoi) 한국교육시설학회 1998 敎育施設 Vol.5 No.1
Nowadays, social environment is rapidly changed toward globalization and information age, and which demands the new paradigm for active utilization of information system in the field of education and many others. The effort to adapt tele-communication technique to educational facilities and the planning to make virtual university come true are needed immediately. Intelligent Building system should be applied to educational facilities to cope with the changing and progressing building system. As a result of the surveying eleven domestic universities, it was found that library management system, administration automation system and office automation system were already introduced, but campus infrastructure such as network system and tele-communication system between buildings in campus have been constructed now. As the conclusion of this study, impeding factors and improvement direction for active utilization of intelligent building systems in university facilities were presented.
Kim, Jae-Ik,Park, So-Jin,Choi, Young-Yoon,Kim, Sang-Bae American Chemical Society 2011 Journal of chemical and engineering data Vol.56 No.5
<P>Molybdenum is chemically combined with other elements and usually extracted from acid leaching a residual solution of molybdenite. Understanding the behavior of the solvents is important for the optimization of the separation procedures. Therefore, binary and ternary liquid−liquid equilibria (LLE) were measured for a mixture of chloroform, acetylacetone, and water at (293.15 to 333.15) K and atmospheric pressure (101.3 ± 0.7 kPa). The solid−liquid equilibrium (SLE) between chloroform and acetylacetone was also determined by visual techniques. This system has a single eutectic point. The experimental LLE and SLE data were well-correlated by the nonrandom two-liquid (NRTL) and universal quasichemical activity coefficient (UNIQUAC) models. In addition, the excess molar volume (<I>V</I><SUP>E</SUP>) and refractivity (<I>n</I><SUB>D</SUB>) for the binary chloroform + acetylacetone mixture were measured at 298.15 K over the entire composition range. The experimental data were satisfactorily fit using the Redlich−Kister polynomial.</P>
Yang, Yi,Bae, Woo Kyun,Nam, Sang-Jip,Jeong, Min-Hye,Zhou, Rui,Park, So-Yeon,Taş,, İ,sa,Hwang, Yun-Ho,Park, Myong-Suk,Chung, Ik Joo,Kim, Kyung Keun,Hur, Jae-Seoun,Kim, Hangun Elsevier 2018 Phytomedicine Vol.40 No.-
<P>Conclusion: The endolichenic fungus EL002332 has potential anticancer activity in gastric cancer and peritoneal carcinomatosis.</P>
수직경사응고(VGF)법에 의한 Si 도핑 GaAs 단결정 성장시 $B_{2}O_{3}$ 첨가에 따른 캐리어 농도 변화
배소익,한창운,Bae, So-Ik,Han, Chang-Woon 한국결정성장학회 2009 韓國結晶成長學會誌 Vol.19 No.2
PBN 도가니를 이용하여 Si이 도핑된 GaAs 단결정을 수직경사 응고법으로 성장시켰다. PBN 도가니에 산화막인 $B_{2}O_{3}$의 양을 $0{\sim}0.2wt%$ 범위에서 변화시키면서, 성장 후 캐리어 농도를 측정하였다. $B_{2}O_{3}$ 첨가량이 증가함에 따라, 초기 0.1 정도의 Si 도판트의 편석계수는 0.01 부근까지 급격히 감소하고, 동시에 캐리어 농도도 감소하는 것을 알 수 있었다. 이는 성장도중 도판트인 Si이 $B_{2}O_{3}$과 반응하며 도너인 Si 양을 감소시키며, 동시에 억셉터인 B 양을 증가시키기 때문으로 보인다. 한편 PBN 도가니 내면에 얇은 유리질의 $B_{2}O_{3}$층 형성이 용이한 고온 산화막 처리가 결함감소에 효과적임을 확인하였다. Si-doped GaAs single crystals were grown by vertical gradient freeze using PBN crucibles. The amount of oxide layer $B_{2}O_{3}$ in PBN crucible was changed($0{\sim}0.2wt%$) and measured the concentration of carriers. The segregation coefficients of Si in GaAs melt decreased rapidly from initial 0.1 to 0.01 as the amount of $B_{2}O_{3}$ increases. At the same time, concentration of carriers was shown to decrease. It is likely that the reaction between dopant Si and $B_{2}O_{3}$ in GaAs melt results in the reduction of Si dopants(donor) while increase in the amount of boron(acceptor). The thin layer of $B_{2}O_{3}$ glass in PBN crucible was proved to be a better way to reduce defect formation rather than the total amount of $B_{2}O_{3}$.