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RISS 인기검색어
- 검색키워드
- 저자 : Archambault, A. (검색결과 4 건)
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Daily localization of partial breast irradiation patients with three-dimensional ultrasound imaging
Sayan, Mutlay,Vergalasova, Irina,Hard, Daphne,Wrigth, Heather,Archambault, Jessica,Gagne, Havaleh,Nelson, Carl,Heimann, Ruth The Korean Society for Radiation Oncology 2019 Radiation Oncology Journal Vol.37 No.4
Purpose: Accurate localization of the lumpectomy cavity during accelerated partial breast radiation (APBR) is essential for daily setup to ensure the prescribed dose encompasses the target and avoids unnecessary irradiation to surrounding normal tissues. Three-dimensional ultrasound (3D-US) allows direct visualization of the lumpectomy cavity without additional radiation exposure. The purpose of this study was to evaluate the feasibility of 3D-US in daily target localization for APBR. Materials and methods: Forty-seven patients with stage I breast cancer who underwent breast conserving surgery were treated with a 2-week course of APBR. Patients with visible lumpectomy cavities on high quality 3D-US images were included in this analysis. Prior to each treatment, X-ray and 3D-US images were acquired and compared to images from simulation to confirm accurate position and determine shifts. Volume change of the lumpectomy cavity was determined daily with 3D-US. Results: A total of 118 images of each modality from 12 eligible patients were analyzed. The average change in cavity volume was 7.8% (range, -24.1% to 14.4%) on 3D-US from simulation to the end-of-treatment. Based on 3D-US, significantly larger shifts were necessary compared to portal films in all three dimensions: anterior/posterior (p = 7E-11), left/right (p = 0.002), and superior/inferior (p = 0.004). Conclusion: Given that the lumpectomy cavity is not directly visible via X-ray images, accurate positioning may not be fully achieved by X-ray images. Therefore, when the lumpectomy cavity is visible on US, 3D-US can be considered as an alternative to X-ray imaging during daily positioning for selected patients treated with APBR, thus avoiding additional exposure to ionizing radiation.
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Daily localization of partial breast irradiation patients with three-dimensional ultrasound imaging
Mutlay Sayan,Irina Vergalasova,Daphne Hard,Heather Wrigth,Jessica Archambault,Havaleh Gagne,Carl Nelson,Ruth Heimann 대한방사선종양학회 2019 Radiation Oncology Journal Vol.37 No.4
Purpose: Accurate localization of the lumpectomy cavity during accelerated partial breast radiation (APBR) is essential for daily setup to ensure the prescribed dose encompasses the target and avoids unnecessary irradiation to surrounding normal tissues. Three-dimensional ultrasound (3D-US) allows direct visualization of the lumpectomy cavity without additional radiation exposure. The purpose of this study was to evaluate the feasibility of 3D-US in daily target localization for APBR. Materials and methods: Forty-seven patients with stage I breast cancer who underwent breast conserving surgery were treated with a 2-week course of APBR. Patients with visible lumpectomy cavities on high quality 3D-US images were included in this analysis. Prior to each treatment, X-ray and 3D-US images were acquired and compared to images from simulation to confirm accurate position and determine shifts. Volume change of the lumpectomy cavity was determined daily with 3D-US. Results: A total of 118 images of each modality from 12 eligible patients were analyzed. The average change in cavity volume was 7.8% (range, -24.1% to 14.4%) on 3D-US from simulation to the end-of-treatment. Based on 3D-US, significantly larger shifts were necessary compared to portal films in all three dimensions: anterior/posterior (p = 7E-11), left/right (p = 0.002), and superior/ inferior (p = 0.004). Conclusion: Given that the lumpectomy cavity is not directly visible via X-ray images, accurate positioning may not be fully achieved by X-ray images. Therefore, when the lumpectomy cavity is visible on US, 3D-US can be considered as an alternative to X-ray imaging during daily positioning for selected patients treated with APBR, thus avoiding additional exposure to ionizing radiation.
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Control of an Exoskeleton Robot Arm with Sliding Mode Exponential Reaching Law
Mohammad H. Rahman,Maarouf Saad,Jean-Pierre Kenné,Philippe S. Archambault 제어·로봇·시스템학회 2013 International Journal of Control, Automation, and Vol.11 No.1
Robots are now working not only in human environments but also interacting with humans, e.g., service robots or assistive robots. A 7DoFs robotic exoskeleton MARSE-7 (motion assistive robotic-exoskeleton for superior extremity) was developed as an assistive robot to provide movement as-sistance and/or ease daily upper-limb motion. In this paper, we highlight the nonlinear control of MARSE-7 using the modified sliding mode exponential reaching law (mSMERL). Conventional sliding control produces chattering which is undesired for this kind of robotic application as it causes damage to the mechanical structure. Compared to conventional sliding control, our approach significantly re-duces chattering and delivers a high dynamic tracking performance. The control architecture was im-plemented on a field-programmable gate array (FPGA) in conjunction with a RT-PC. In experiments, trajectory tracking that corresponds to typical passive arm movement exercises for single and multi joint movements were performed to evaluate the performance of the developed robot and the controller. Experimental results demonstrate that the MARSE-7 can effectively track the desired trajectories.
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Kim, Daeun,Jin, Bingkui,Je, Byoung Il,Choi, Youngmi,Kim, Byung Sup,Jung, Hee-Jeong,Nou, Ill-Sup,Park, Younghoon,Archambault, A. Canadian Science Publishing 2018 Genome Vol.61 No.10
<P> Reductions in growth and quality due to powdery mildew (PM) disease cause significant economic losses in tomato production. Oidium neolycopersici was identified as the fungal species responsible for tomato PM disease in South Korea in the present study, based on morphological and internal transcribed spacer DNA sequence analyses of PM samples collected from two remote regions (Muju and Miryang). The genes involved in resistance to this pathogen in the tomato accession ‘KNU-12’ (Solanum lycopersicum var. cerasiforme) were evaluated, and the inheritance of PM resistance in ‘KNU-12’ was found to be conferred via simple Mendelian inheritance of a mutant allele of the PM susceptibility locus Ol-2 (SlMlo1). Full-length cDNA analysis of this newly identified mutant allele (Slmlo1.1) showed that a 1-bp deletion in its coding region led to a frameshift mutation possibly resulting in SlMlo1 loss-of-function. An alternatively spliced transcript of Slmlo1.1 was observed in the cDNA sequences of ‘KNU-12’, but its direct influence on PM resistance is unclear. A derived cleaved amplified polymorphic sequence (dCAPS) and a high-resolution melting (HRM) marker were developed based on the 1-bp deletion in Slmlo1.1, and could be used for efficient marker-assisted selection (MAS) using ‘KNU-12’ as the source for durable and broad-spectrum resistance to PM. </P>
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