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Prevalence of Irritable Bowel Syndrome: A Community Based Study From Northern India
( Govind K Makharia ),( Anil K Verma ),( Ritvik Amarchand ),( Anil Goswami ),( Prashant Singh ),( Abhishek Agnihotri ),( Faizul Suhail ),( Anand Krishnan ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2011 Journal of Neurogastroenterology and Motility (JNM Vol.17 No.1
Background/Aims The prevalence of irritable bowel syndrome (IBS) varies from 4% to 20% in different Asian nations. Prevalence of IBS in native North Indian community is not known. Methods Between November 2008 to December 2009, we estimated the prevalence of IBS in a rural community of Ballabgarh block, located in Haryana state. A structured questionnaire based on Rome Ⅲ module was used to collect symptoms related to IBS from all the participants in a door to door survey. A Rome Ⅲ criterion was used for diagnosis of IBS. IBS was further classified based on predominance of symptoms as constipation predominant, diarrhea predominant, mixed and unspecified based on Rome Ⅲ module. Results There were 4,767 participants (mean age 34.6±10.8, males 50%). Overall, 555 (11.6%; 95% CI, 10.7-12.5) had constipation, 542 (11.4%; 95% CI, 10.5-12.3) diarrhea and 823 (17.3%; 95% CI, 16.2-18.4) abdominal pain. The overall prevalence of IBS was 4% (95% CI, 3.5-4.6). The prevalence of constipation predominant IBS was 0.3% (95% CI, 0.16-0.49), diarrhea predominant IBS 1.5% (95% CI, 1.18-1.90), mixed IBS 1.7% (95% CI, 1.35-2.11) and unsubtyped IBS 0.5% (95% CI, 0.32-0.75). The prevalence of IBS was significantly higher in females compared with males (4.8% vs 3.2%, P=0.008). However, there was no significant difference between males and females in the prevalence of different subtypes of IBS. The prevalence increased with age. Conclusions The prevalence of IBS in a North Indian community is 4%. IBS poses a significant burden on the rural adults. (J Neurogastroenterol Motil 2011;17:82-87)
An Identity-based Ring Signcryption Scheme: Evaluation for Wireless Sensor Networks
Sharma, Gaurav,Bala, Suman,Verma, Anil K. The Institute of Electronics and Information Engin 2013 IEIE Transactions on Smart Processing & Computing Vol.2 No.2
Wireless Sensor Networks consist of small, inexpensive, low-powered sensor nodes that communicate with each other. To achieve a low communication cost in a resource constrained network, a novel concept of signcryption has been applied for secure communication. Signcryption enables a user to perform a digital signature for providing authenticity and public key encryption for providing message confidentiality simultaneously in a single logical step with a lower cost than that of the sign-then-encrypt approach. Ring signcryption maintains the signer's privacy, which is lacking in normal signcryption schemes. Signcryption can provide confidentiality and authenticity without revealing the user's identity of the ring. This paper presents the security notions and an evaluation of an ID-based ring signcryption scheme for wireless sensor networks. The scheme has been proven to be better than the existing schemes. The proposed scheme was found to be secure against adaptive chosen ciphertext ring attacks (IND-IDRSC-CCA2) and secure against an existential forgery for adaptive chosen message attacks (EF-IDRSC-ACMA). The proposed scheme was found to be more efficient than scheme for Wireless Sensor Networks reported by Qi. et al. based on the running time and energy consumption.
Prasenjit Das,Gaurav PS Gahlot,Alka Singh,Vandana Baloda,Ramakant Rawat,Anil K Verma,Gaurav Khanna,Maitrayee Roy,Archana George,Ashok Singh,Aasma Nalwa,Prashant Ramteke,Rajni Yadav,Vineet Ahuja,Vishnu 대한장연구학회 2019 Intestinal Research Vol.17 No.3
Background/Aims: The existing histological classifications for the interpretation of small intestinal biopsies are based on qualitative parameters with high intraobserver and interobserver variations. We have developed and propose a quantitative histological classification system for the assessment of intestinal mucosal biopsies. Methods: We performed a computer-assisted quantitative histological assessment of digital images of duodenal biopsies from 137 controls and 124 patients with celiac disease (CeD) (derivation cohort). From the receiver-operating curve analysis, followed by multivariate and logistic regression analyses, we identified parameters for differentiating control biopsies from those of the patients with CeD. We repeated the quantitative histological analysis in a validation cohort (105 controls and 120 patients with CeD). On the basis of the results, we propose a quantitative histological classification system. The new classification was compared with the existing histological classifications for interobserver and intraobserver agreements by a group of qualified pathologists. Results: Among the histological parameters, intraepithelial lymphocyte count of ≥25/100 epithelial cells, adjusted villous height fold change of ≤0.7, and crypt depth-to-villous height ratio of ≥0.5 showed good discriminative power between the mucosal biopsies from the patients with CeD and those from the controls, with 90.3% sensitivity, 93.5% specificity, and 96.2% area under the curve. Among the existing histological classifications, our quantitative histological classification showed the highest intraobserver (69.7%–85.03%) and interobserver (24.6%–71.5%) agreements. Conclusions: Quantitative assessment increases the reliability of the histological assessment of mucosal biopsies in patients with CeD. Such a classification system may be used for clinical trials in patients with CeD.