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        Screening of the growth of thymus of human fetuses

        Adil Asghar,Mohammad Rehan Asad,Shagufta Naaz,Mamta Rani 대한해부학회 2019 Anatomy & Cell Biology Vol.52 No.4

        The thymus is a lymphoepithelial organ, and its morphometry is commonly utilized for surveillance of the immunological status of fetus and neonates. Many studies showed that fetal thymus size is used as a prognostic indicator for pregnancy-related disorders such as eclampsia, preterm labor, and gestational diabetes. The study aims to establish reference ranges of the normal fetal thymus size between 12 and 40 weeks of gestational age (GA). The study was conducted on 89 fetuses. They were dissected to capture the morphometry of thymus: transverse diameter, perimeter, and weight. Considering these parameters were dependent variables of GA and gestational weight (GW). Their relationship was studied by a multiple regression model. The best fit models in predicting thymic dimensions as a function of GA and GW were determined using regression analysis. Mean transverse diameter, perimeter, and thymus weight was 33.45±2.91 mm, 125.72±55.4 mm, and 3.078±3.06 g, respectively. They were increased throughout pregnancy as GA and GW advanced. The regression equation for a transverse diameter of the thymus as a function of GA was (0.303×GA–4.885, R2=0.8196) and for the perimeter of the thymus was (1.0212×GA–15.24, R2=0.8666). Reference ranges and baseline data of the normal fetal thymic dimensions between 12 and 40 weeks of GA have been established.

      • KCI등재후보

        The prevalence and distribution of the variants of Gantzer’s muscle: a meta-analysis of cadaveric studies

        Adil Asghar,Rakesh Kumar Jha,Apurba Patra,Binita Chaudhary,Brijendra Singh 대한해부학회 2022 Anatomy & Cell Biology Vol.55 No.1

        The Gantzer’s muscle is often present in the flexor compartment of the forearm. It lies underneath flexor digitorum superficialis and compresses the anterior interosseous nerve. Furthermore, this muscle frequently bestows an accessory muscle of flexor pollicis longus or flexor digitorum profundus, or sometimes together. The current meta-analysis aims to compute the prevalence of subtypes of Gantzer’s muscle. Major electronic databases (PubMed, Scopus, Google Scholar, etc.) were searched for title and abstract. After removing the duplicate citations, the titles/abstracts were shortlisted with the help of inclusion and exclusion criteria. The shortlisted titles/abstracts were downloaded or collected from the library. The data of all subtypes of Gantzer’s muscle were pooled from shortlisted published manuscripts for meta-analysis. The pooled estimate of other anatomical characteristics was also observed. A total of 59 cadaveric studies of sample size 5,903 were evaluated for pooled prevalence of flexor pollicis longus (accessory head). Similarly, the authors evaluated 14 studies of 1,627 upper limbs for flexor digitorum profundus (accessory head). The unit of analysis was per 100 upper limbs. The Pooled prevalence of accessory muscle of flexor pollicis longus and flexor digitorum profundus were 48% (95% CI, 44%-52%) and 17% (95% CI, 13%-21%), respectively. The Gantzer’s muscle is present in 2/3rd of the upper limbs. Accessory head of flexor pollicis longus is almost three times more common than the accessory head of flexor digitorum profundus. A classification of Gantzer’s muscle is needed to reduce the ignorance of these variants.

      • KCI등재

        The Role of Transverse Arch in Foot Stiffness and Its Clinical Implications

        Adil Asghar,Shagufta Naaz 대한체질인류학회 2021 해부·생물인류학 (Anat Biol Anthropol) Vol.34 No.3

        The human has the most evolved arched feet. Initially, a transverse arch developed in feet like the carpal arch till modern human arches evolved, which included a longitudinal and transverse arch.

      • KCI등재

        Exploring the variations of the pancreatic ductal system: a systematic review and meta analysis of observational studies

        Adil Asghar,Ravi Kant Narayan,Nagavalli Basavanna Pushpa,Apurba Patra,Kumar Satish Ravi,R. Shane Tubbs 대한해부학회 2024 Anatomy & Cell Biology Vol.57 No.1

        The exocrine part of the pancreas has a duct system called the pancreatic ductal system (PDS). Its mechanism of development is complex, and any reorganization during early embryogenesis can give rise to anatomical variants. The aim of this study is to collect, classify, and analyze published evidence on the importance of anatomical variants of the PDS, addressing gaps in our understanding of such variations. The MEDLINE, Web of Science, Embase, and Google Scholar databases were searched to identify publications relevant to this review. R studio with meta-package was used for data extraction, risk of bias estimation, and statistical analysis. A total of 64 studies out of 1,778 proved suitable for this review and metanalysis. The meta-analysis computed the prevalence of normal variants of the PDS (92% of 10,514 subjects). Type 3 variants and “descending” subtypes of the main pancreatic duct (MPD) predominated in the pooled samples. The mean lengths of the MPD and accessory pancreatic duct (APD) were 16.53 cm and 3.36 cm, respectively. The mean diameters of the MPD at the head and the APD were 3.43 mm and 1.69 mm, respectively. The APD was present in only 41% of samples, and the long type predominated. The pancreatic ductal anatomy is highly variable, and the incorrect identification of variants may be challenging for surgeons during ductal anastomosis with gut, failure to which may often cause ductal obstruction or pseudocysts formation.

      • Structural detection of variation in Poisson's ratio: Monitoring system for zigzag double walled carbon nanotubes

        Hussain, Muzamal,Asghar, Sehar,Ayed, Hamdi,Khadimallah, Mohamed A.,Alshoaibi, Adil,Tounsi, Abdelouahed Techno-Press 2022 Advances in nano research Vol.12 No.4

        In this paper, natural frequency curves are presented for three specific end supports considering distinct values of nonlocal parameter. The vibrational behavior of zigzag double walled carbon nanotubes is investigated using wave propagation with nonlocal effect. Frequency spectra of zigzag (12, 0) double walled carbon nanotubes have been analyzed with proposed model. Effects of nonlocal parameters have been fully investigated on the natural frequency against against variation of Poisson's ratio. A slow increase in frequencies against variation of Poisson's ratio also indicates insensitivity of it for suggested nonlocal model. Moreover, decrease in frequencies with increase in nonlocal parameter authenticates the applicability of nonlocal Love shell model. Also the frequency curves for C-F are lower throughout the computation than that of C-C curves.

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