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      • KCI등재

        학령기 아동용 스마트기기를 사용한 기억력 평가과제의 개발 및 타당도 검증 연구

        신민섭(Min-Sup Shin),이진주(Jinjoo Lee),어윤정(Yunjung Eo),오서진(Seojin Oh),이정은(Jungeun Lee),김일중(Illjung Kim),홍초롱(Chorong Hong) 대한소아청소년정신의학회 2016 소아청소년정신의학 Vol.27 No.2

        Objectives: The aim of this study was to develop auditory-verbal and visual-spatial memory tasks using smart devices for children aged 8 to 10 years and examine their validity. Methods: One-hundred and fourteen school-aged children were recruited through internet advertising. We developed memory tasks assessing auditory-verbal memory, visual-spatial memory, and working memory, and then examined their construct validity by examining the developmental trend of the children’s mean scores with age. In order to examine the concurrent validity of the tasks, we conducted correlation analyses between the children’s scores on the newly developed auditory-verbal, visual-spatial memory and working memory tasks and their scores on well-known standardized tests of memory and working memory, including the auditory-verbal memory subtests of the Korean Luria-Nebraska Neuropsychological Battery for Children, Korean Rey-Osterrieth Complex Figure Test, digit span and arithmetic subtest of Korean Educational Development Institute Wechsler Intelligence Scale for Children Revised, and Corsi block test. Results: The memory and working memory scores measured by the newly developed tasks tended to increase with age. Further, there were significant correlations between the scores of the four cognitive tasks and the corresponding scores of the standardized assessment tools. Conclusion: This study revealed promising evidence for the validity of the memory tasks using smart devices, suggesting their utility for school-aged children in research and clinical settings.

      • KCI등재

        학령전기 아동 대상의 스마트기기를 사용한 전산화 주의력 평가과제의 개발 및 타당도 검증 연구

        신민섭(Min-Sup Shin),이진주(Jinjoo Lee),오서진(Seojin Oh),김일중(Illjung Kim),홍초롱(Chorong Hong),김수림(Sulim Kim) 대한소아청소년정신의학회 2015 소아청소년정신의학 Vol.26 No.2

        Objectives:The aim of this study was to develop computerized attention tasks using smart devices for preschool aged children for assessment of auditory attention, visual attention, and attention shifting abilities. We then evaluated their construct and concurrent validity of them. Methods:Sixty-seven 5- to 7-year-old children attending kindergarten were recruited. Newly developed computerized attention tasks and existing standardized attention tests such as Advanced Test of Attention (ATA) and Children’s Color Trails Test-2 (CCTT-2) were successively administered. To examine the concurrent validity of these tasks, correlation coefficients between the participants’ scores on the newly developed tasks and the scores on well-known measures were calculated for assessment of each component construct. We also examined the construct validity of the tasks using the developmental trend of the auditory attention, visual attention, and attention shifting abilities with age. Results:Significant correlations were observed between the scores of computerized attention tasks using smart devices and corresponding scores of ATA-auditory task, visual task, and CCTT-2. And there were significant linear increasing trends of correct scores with age from 5 to 7 years. Conclusion:This study provides promising evidence for the utility of computerized attention tasks using smart devices for preschool-aged children.

      • 허혈성 뇌졸중의 위험 인자로서의 아포지방단백 B/A1 비

        초롱,기숙 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.1

        Objectives: According to current knowledge, apolipoprotein B/A1 (apoB/A1) ratio is like to be risk factor in coronary artery disease. There is evidence form case-control studies that apoB/A1 ratio may be a superior to LDL and HDL cholesterol in discriminating coronary artery disease case subject from control subject. However, relationship between apoB/A1 ratio and cerebral ischemic stroke is undefined. The main object of this study is to determine whether the risk of cerebral ischemic stroke is related to levels of apoB/A1. Methods: The study group included 643 patients (Men, 372; Women, 271) who diagnosed cerebral ischemic stroke between January 2008 to December 2010. The control groups were composed of 378 patients (Men, 139; Women, 239) who diagnosed other neurological disease. The correlation between lipid profiles and odds ratio of 10 preliminary risk factors (total cholesterol, triglyceride, LDL, HDL, apoA1, apoB, apoB/A1 ratio, non HDL, total cholesterol/HDL ratio, LDL/HDL ratio) for stroke were analyzed. Results: ApoB/A1 ratio was significantly increased in case patients compared with control subjects. Multivariate logistic regression analysis identified decrease of apoB/A1 ratio (odds ratio [OR], 1.583; 95% confidence intercal [CI], 1.105∼2.269) as significantly associated with stroke. Individual apoA1 (OR, 1.303; 95% CI, 0.967∼1.755) and apoB (OR, 1.397; 95% CI, 0.773∼2.523) were also not significantly associated with cerebral ischemic stroke. Conclusion: Increase of apoB/A1 ratio is associated with an increase risk of cerebral ischemic stroke. Use of apoB/A1 ratio is efficient as conventional lipids, for the identification of subjects at increased risk of stroke. So apoB/A1 ratio to standard lipid profile testing could improve the evaluation of risk factors of cerebral ischemic stroke.

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